Imperial College London


Faculty of Natural SciencesDepartment of Chemistry

Senior Lecturer



+44 (0)20 7594 3438k.jelfs Website




207AMolecular Sciences Research HubWhite City Campus






BibTex format

author = {Reiss, PS and Little, MA and Santolini, V and Chong, SY and Hasell, T and Jelfs, KE and Briggs, ME and Cooper, AI},
doi = {10.1002/chem.201603593},
journal = {Chemistry},
pages = {16547--16553},
title = {Periphery-functionalized porous organic cages},
url = {},
volume = {22},
year = {2016}

RIS format (EndNote, RefMan)

AB - By synthesizing derivatives of a trans-1,2-diaminocyclohexane precursor, three new functionalized porous organic cages were prepared with different chemical functionalities on the cage periphery. The introduction of twelve methyl groups (CC16) resulted in frustration of the cage packing mode, which more than doubled the surface area compared to the parent cage, CC3. The analogous installation of twelve hydroxyl groups provided an imine cage (CC17) that combines permanent porosity with the potential for post-synthetic modification of the cage exterior. Finally, the incorporation of bulky dihydroethanoanthracene groups was found to direct self-assembly towards the formation of a larger [8+12] cage, rather than the expected [4+6], cage molecule (CC18). However, CC18 was found to be non-porous, most likely due to cage collapse upon desolvation.
AU - Reiss,PS
AU - Little,MA
AU - Santolini,V
AU - Chong,SY
AU - Hasell,T
AU - Jelfs,KE
AU - Briggs,ME
AU - Cooper,AI
DO - 10.1002/chem.201603593
EP - 16553
PY - 2016///
SN - 0861-9255
SP - 16547
TI - Periphery-functionalized porous organic cages
T2 - Chemistry
UR -
UR -
VL - 22
ER -