Imperial College London

Mr Konstantinos Kalyviotis (He/him)

Faculty of EngineeringDepartment of Bioengineering

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Royal School of MinesSouth Kensington Campus

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Summary

 

Summary

Konstantinos is a postdoctoral Research Associate (PDRA) at the Department of Bioengineering working with Dr Periklis (Laki) Pantazis. Within the Laboratory of Advanced Optical Precision Imaging, he continues his work on developing an advanced optical precision imaging toolkit. This toolkit encompasses a novel biosensor for the mechanosensitive ion channel Piezo1, named GenEPi, new improved green-to-red photoconvertible fluorescent proteins for primed conversion, a cutting-edge volumetric imaging microscope (λ-OPM) with Raman capabilities in collaboration with Dr Rowlands' lab, and the first biodegradable Second Harmonic Generation (SHG) nanoprobes, called bioharmonophores, that could transform biomedical diagnostic and therapeutic imaging and photodynamic therapy.

Konstantinos was recently honoured with the 2023 Christine Beattie Award from the International Zebrafish Society (IZFS) which acknowledges early-career zebrafish scientists who "demonstrate excellence in zebrafish research and exhibit promise as future leaders in the field".

Konstantinos is a co-founding member and chairperson of the Young Researcher Committee (YoRC) of the European Zebrafish Society (EZS), elected member of the EZS Board and part of the Organising Committee of the London Zebrafish Club Special Interest Group (SIG) funded by the Genetics Society.

Konstantinos studied Molecular Biology and Genetics at the Democritus University of Thrace in Greece and obtained a Master's degree in Translational Research in Biomedicine. Before joining Imperial College, he was a Research Assistant at the Laboratory of Nano Bio Imaging at the Department of Biosystems Science and Engineering (D-BSSE) at ETH Zurich in Basel, working on fluorescent protein engineering.

Selected Publications

Journal Articles

Kalyviotis K, Pantazis P, 2023, Primed conversion: The emerging player of precise and nontoxic photoconversion., J Microsc

Pantazis P, Pantazis P, Yaganoglu S, et al., 2023, Highly specific and non-invasive imaging of Piezo1-dependent activity across scales using GenEPi, Nature Communications, Vol:14, ISSN:2041-1723, Pages:1-16

Kalyviotis K, 2021, Primed conversion: the Basics

Sonay AY, Kalyviotis K, Yaganoglu S, et al., 2021, Biodegradable harmonophores for targeted high-resolution in vivo tumor imaging, ACS Nano, Vol:15, ISSN:1936-0851, Pages:4144-4154

Welling M, Kalyviotis K, Pantazis P, 2020, Primed track: reliable volumetric single-cell tracking and lineage tracing of living specimen with dual-labeling approaches, Bio-protocol, Vol:10, ISSN:2331-8325, Pages:1-10

Chytoudis-Peroudis CC, Siskos N, Kalyviotis K, et al., 2018, Spatial distribution of the full-length members of the Grg family during embryonic neurogenesis reveals a “Grg-mediated repression map” in the mouse telencephalon, PLOS One, Vol:13, ISSN:1932-6203

Chapters

Kalyviotis K, Qin H, Pantazis P, 2020, Chapter 19 - PhOTO zebrafish and primed conversion: advancing the mechanistic view of development and disease, Behavioral and Neural Genetics of Zebrafish, Editor(s): Gerlai, Academic Press, Pages:309-322

More Publications