Imperial College London
Alternate

Professor Karim Meeran

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Professor of Endocrinology
 
 
 
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Contact

 

+44 (0)20 8846 1065k.meeran

 
 
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Location

 

9E05Charing Cross HospitalCharing Cross Campus

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Summary

 

Publications

Citation

BibTex format

@article{Almazrouei:2019:qjmed/hcz071,
author = {Almazrouei, R and Model, D and Meeran, K},
doi = {qjmed/hcz071},
journal = {QJM: An International Journal of Medicine},
pages = {811--812},
title = {Sheehan's like syndrome in a man},
url = {http://dx.doi.org/10.1093/qjmed/hcz071},
volume = {112},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - An 84-year-old physician self-diagnosed that he had a pituitary tumour when he was found to have a bilateral upper quadrantanopia on routine eye testing. Magnetic resonance imaging (MRI) confirmed a large non-functioning pituitary macroadenoma associated with chiasmal compression. Investigation showed partial hypopituitarism with disconnection hyperprolactinaemia [prolactin 1095 mU/L (60–300)]. He was treated with hormonal replacement consisting of thyroxin 100 µg and prednisolone 3 mg and was offered transphenoidal hypophysectomy, but chose a conservative approach. Two years later, his visual fields worsened (Figure 1A) corresponding to an increase in macrodenoma size. Subsequently, he fell and fractured his left shoulder, which became infected, requiring surgery. Immediately after the shoulder surgery, he became hypotensive and vomited several times, and his visual fields became restricted. MRI showed pituitary infarction (Figure 1B), and he did not require surgical intervention. A few weeks later, he noticed dramatic improvement in his vision. His prolactin level dropped from a peak level of 1095 to 48 mU/L (60–300), suggesting lactotroph infarction. Repeated pituitary MRI showed dramatic reduction in the height of the pituitary macroadenoma consistent with the improvement in his visual fields (Figure 1C).
AU  - Almazrouei,R
AU  - Model,D
AU  - Meeran,K
DO  - qjmed/hcz071
EP  - 812
PY  - 2019///
SN  - 1460-2393
SP  - 811
TI  - Sheehan's like syndrome in a man
T2  - QJM: An International Journal of Medicine
UR  - http://dx.doi.org/10.1093/qjmed/hcz071
UR  - https://www.ncbi.nlm.nih.gov/pubmed/30911765
UR  - http://hdl.handle.net/10044/1/69538
VL  - 112
ER  -
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