Imperial College London
Alternate

Professor Karim Meeran

Faculty of Medicine, Department of Metabolism, Digestion and Reproduction

Professor of Endocrinology
 
 
 
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Contact

 

+44 (0)20 8846 1065k.meeran

 
 
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Location

 

9E05Charing Cross HospitalCharing Cross Campus

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Summary

 

Publications

Citation

BibTex format

@article{Hameed:2020:10.1111/dom.14207,
author = {Hameed, S and Salem, V and Alessimii, H and Scholtz, S and Dar, O and Miras, AD and Meeran, K and Bloom, SR and Ahmed, AR and Purkayastha, S and Chahal, H and Tan, T},
doi = {10.1111/dom.14207},
journal = {Diabetes, Obesity and Metabolism: a journal of pharmacology and therapeutics},
pages = {270--275},
title = {Imperial Satiety Protocol: A new non-surgical weight-loss programme, delivered in a health care setting, produces improved clinical outcomes for people with obesity},
url = {http://dx.doi.org/10.1111/dom.14207},
volume = {23},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - ‘Imperial Satiety Protocol’ (I-SatPro) is a new multifaceted approach to weight loss for people with obesity (PwO), encompassing dietary advice, time-restricted eating, physical activity and coaching to support behaviour change. Participants (n = 84) attended fortnightly I-SatPro group sessions for 30 weeks, with 70% of participants completing. On completion at 30 weeks, the mean weight loss was 15.2 ± 1.1 kg (13.2 ± 0.8% from baseline, P < .0001), which was maintained to 52 weeks (16.6 ± 1.5 kg, 14.1 ± 1.2%, P < .0001). Weight loss was not associated with reduced energy expenditure. In participants with type 2 diabetes and pre-diabetes (n = 16), glycated haemoglobin fell from 50 to 43 mmol/mol (P < .01). Systolic blood pressure fell by 12 mmHg (P < .0001). Triglycerides fell by 0.37 mmol/L (P < .01) and high-density lipoprotein rose by 0.08 mmol/L (P < .01). Short Form-36 (SF-36) functioning and wellbeing scores increased in all domains post I-SatPro intervention. For selected PwO, I-SatPro delivers clinically meaningful weight loss, and the potential for long-term health and wellbeing improvements.
AU  - Hameed,S
AU  - Salem,V
AU  - Alessimii,H
AU  - Scholtz,S
AU  - Dar,O
AU  - Miras,AD
AU  - Meeran,K
AU  - Bloom,SR
AU  - Ahmed,AR
AU  - Purkayastha,S
AU  - Chahal,H
AU  - Tan,T
DO  - 10.1111/dom.14207
EP  - 275
PY  - 2020///
SN  - 1462-8902
SP  - 270
TI  - Imperial Satiety Protocol: A new non-surgical weight-loss programme, delivered in a health care setting, produces improved clinical outcomes for people with obesity
T2  - Diabetes, Obesity and Metabolism: a journal of pharmacology and therapeutics
UR  - http://dx.doi.org/10.1111/dom.14207
UR  - http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcApp=PARTNER_APP&SrcAuth=LinksAMR&KeyUT=WOS:000577401500001&DestLinkType=FullRecord&DestApp=ALL_WOS&UsrCustomerID=1ba7043ffcc86c417c072aa74d649202
UR  - https://dom-pubs.onlinelibrary.wiley.com/doi/10.1111/dom.14207
UR  - http://hdl.handle.net/10044/1/89338
VL  - 23
ER  -
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