@inproceedings{Mirza:2017, author = {Mirza, K and Zuliani, C and Hou, B and Ng, FS and Peters, N and Toumazou, C}, title = {An Individually Addressable Microneedle Device for Real-Time Wireless pH Monitoring}, year = {2017} }
TY - CPAPER AB - This paper describes the development of an array of individually addressable pH sensitive microneedles using injection moulding and their integration within a portable device for real-time wireless recording of pH distributions in biological samples. The fabricated microneedles are subjected to gold pat- terning followed by electrodeposition of iridium oxide to sensitize them to 0.07 units of pH change. Miniaturised electronics suitable for the sensors readout, analog-to-digital conversion and wireless transmission of the potentiometric data are embodied within the device, enabling it to measure real-time pH of soft biological samples such as muscles. In this paper, real-time recording of the cardiac pH distribution, during ischemia followed by reperfusion cycles in cardiac muscles of male Wistar rats has been demonstrated by using the microneedle array. AU - Mirza,K AU - Zuliani,C AU - Hou,B AU - Ng,FS AU - Peters,N AU - Toumazou,C PY - 2017/// TI - An Individually Addressable Microneedle Device for Real-Time Wireless pH Monitoring ER -