Imperial College London

DrKonstantinNikolic

Faculty of EngineeringDepartment of Electrical and Electronic Engineering

Visiting Professor
 
 
 
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Contact

 

+44 (0)20 7594 1594k.nikolic

 
 
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Location

 

Bessemer 420CBessemer BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@inproceedings{Troiani:2016:10.1117/12.2209335,
author = {Troiani, F and Nikolic, K and Constandinou, TG},
doi = {10.1117/12.2209335},
title = {Optical Coherence Tomography for detection of compound action potential in Xenopus Laevis sciatic nerve},
url = {http://dx.doi.org/10.1117/12.2209335},
year = {2016}
}

RIS format (EndNote, RefMan)

TY  - CPAPER
AB - Due to optical coherence tomography (OCT) high spatial and temporal resolution, this technique could be used to observe the quick changes in the refractive index that accompany action potential. In this study we explorethe use of time domain Optical Coherence Tomography (TD-OCT) for real time action potential detection in ex vivo Xenopus Laevis sciatic nerve. TD-OCT is the easiest and less expensive OCT technique and, if successful indetecting real time action potential, it could be used for low cost monitoring devices. A theoretical investigation into the order of magnitude of the signals detected by a TD-OCT setup is provided by this work. A lineardependence between the refractive index and the intensity changes is observed and the minimum SNR for which the setup could work is found to be SNR = 2 x10.
AU - Troiani,F
AU - Nikolic,K
AU - Constandinou,TG
DO - 10.1117/12.2209335
PY - 2016///
TI - Optical Coherence Tomography for detection of compound action potential in Xenopus Laevis sciatic nerve
UR - http://dx.doi.org/10.1117/12.2209335
UR - http://hdl.handle.net/10044/1/30124
ER -