Publications
477 results found
Schmidt A, Bowles CT, Noor M, et al., 2011, Direct Comparison of the Performance Characteristics of the Thoratec Heart Mate II, Heartware HVAD and Jarvik 2000 Left Ventricular Assist Devices, 31st Annual Meeting and Scientific Sessions on International-Society-for-Heart-and-Lung-Transplantation, Publisher: ELSEVIER SCIENCE INC, Pages: S213-S213, ISSN: 1053-2498
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- Citations: 1
Bowles CT, Noor M, Schmidt A, et al., 2011, Successful Treatment of Implantable Rotary Left Ventricular Assist Device (LVAD) Thrombus Is Associated with Normalisation of Acoustic Properties, 31st Annual Meeting and Scientific Sessions on International-Society-for-Heart-and-Lung-Transplantation, Publisher: ELSEVIER SCIENCE INC, Pages: S98-S98, ISSN: 1053-2498
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- Citations: 4
Starmans-Kool MJ, Stanton AV, Xu YY, et al., 2011, High dietary salt intake increases carotid blood pressure and wave reflection in normotensive healthy young men, JOURNAL OF APPLIED PHYSIOLOGY, Vol: 110, Pages: 468-471, ISSN: 8750-7587
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- Citations: 25
Lewalle A, Parker KH, 2011, Axisymmetric Optical-Trap Measurement of Red Blood Cell Membrane Elasticity, JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, Vol: 133, ISSN: 0148-0731
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- Citations: 2
Cao S, Bharath A, Parker K, et al., 2011, Joint Spatio-Temporal Registration and Microvasculature Segmentation of Retinal Angiogram Sequences, 2011 ANNUAL INTERNATIONAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY (EMBC), Pages: 2618-2621, ISSN: 1557-170X
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- Citations: 1
Waters SL, Alastruey J, Beard DA, et al., 2011, Theoretical models for coronary vascular biomechanics: Progress & challenges, Progress in Biophysics and Molecular Biology, Vol: 104, Pages: 49-76
Rogers M, Leong C, Niu X, et al., 2011, Optimisation of a microfluidic analysis chamber for the placement of microelectrodes, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, Vol: 13, Pages: 5298-5303, ISSN: 1463-9076
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- Citations: 22
Bell CG, Anastassiou CA, O'Hare D, et al., 2011, Theory of high frequency, large-amplitude sinusoidal voltammetry for ideal surface-confined redox systems, Electrochimica Acta
Li Y, Borlotti A, Parker KH, et al., 2011, Variation of wave speed determined by the PU-loop with proximity to a reflection site, 33rd Annual International Conference of the IEEE Engineering-in-Medicine-and-Biology-Society (EMBS), Publisher: IEEE, Pages: 199-202, ISSN: 1557-170X
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- Citations: 3
Bell CG, Anastassiou CA, O'Hare D, et al., 2011, Large-amplitude ac voltammetry: theory for reversible redox reactions in the ``slow scan limit approximation", Electrochimica Acta, Pages: 6131-6141
Bell CG, Anastassiou CA, O'Hare D, et al., 2011, Theory of large-amplitude sinusoidal voltammetry for reversible redox reactions, Electrochimica Acta
Davies JE, Tillin T, Malaweera A, et al., 2010, Pressure-Independent Pulsatility Index (PIPI) Independently Predicts Cardiovascular Events in the Cafe Sub-Study of Ascot, CIRCULATION, Vol: 122, ISSN: 0009-7322
Sen S, Hadjiloizou N, Baksi J, et al., 2010, Myocardial mechanism of angina in aortic stenosis identified in subjects undergoing transcatheter aortic valve implantation (TAVI), Publisher: NATURE PUBLISHING GROUP, Pages: 689-689, ISSN: 0950-9240
Simonds AK, Hanak A, Chatwin M, et al., 2010, Evaluation of droplet dispersion during non-invasive ventilation, oxygen therapy, nebuliser treatment and chest physiotherapy in clinical practice: implications for management of pandemic influenza and other airborne infections, HEALTH TECHNOLOGY ASSESSMENT, Vol: 14, Pages: 131-+, ISSN: 1366-5278
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- Citations: 151
Davies JE, Lacy PS, Cruickshank K, et al., 2010, Excess pressure is higher in atenolol-treated individuals and independently predicts cardiovascular events in the CAFE substudy of ASCOT, ESC Congress, Publisher: OXFORD UNIV PRESS, Pages: 902-902, ISSN: 0195-668X
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- Citations: 2
Davies JE, Sen S, Hadjiloizou N, et al., 2010, Reversed coronary reserve responses explain angina in severe aortic stenosis: assessment in subjects undergoing transcatheter aortic valve implantation (TAVI), ESC Congress, Publisher: OXFORD UNIV PRESS, Pages: 313-314, ISSN: 0195-668X
Witt NW, Chapman N, Thom SAM, et al., 2010, A novel measure to characterise optimality of diameter relationships at retinal vascular bifurcations., Artery Res, Vol: 4, Pages: 75-80, ISSN: 1872-9312
Conventionally, the relationship between parent and daughter vessels at vascular bifurcations has been expressed by the junction exponent (x), and deviations of this parameter from the optimal conditions predicted by Murray's law (x = 3) have been shown to be associated with vascular disease. However, the junction exponent is normally calculated iteratively from diameter measurements, and Monte-Carlo simulation studies show the junction exponent to be biased in the presence of measurement noise.We present an alternative parameter, referred to as optimality ratio, that is simpler to compute and also more robust in the presence of noise.To demonstrate the sensitivity of the optimality ratio to alterations in topography of the retinal vascular network, we analysed the effect of inducing endothelial dysfunction by infusion of NG-monomethyl-l-arginine (l-NMMA), a nitric oxide synthase inhibitor, compared to placebo in a double-blind crossover study. The optimality ratio showed a significant increase (p = 0.03) during infusion of l-NMMA compared to placebo.We propose that a measure of the extent of departure of optimality ratio from its optimal value of 2(-1/3) may be a useful indicator of microvascular endothelial dysfunction in vivo.
Manisty C, Mayet J, Tapp RJ, et al., 2010, Wave Reflection Predicts Cardiovascular Events in Hypertensive Individuals Independent of Blood Pressure and Other Cardiovascular Risk Factors An ASCOT (Anglo-Scandinavian Cardiac Outcome Trial) Substudy, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 56, Pages: 24-30, ISSN: 0735-1097
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- Citations: 82
Davies JE, Sen S, Hadjiloizou N, et al., 2010, ACUTE CHANGES IN CORONARY HAEMODYNAMIC IN PATIENTS UNDERGOING TRANSCATHETER AORTIC VALVE IMPLANTATION, Annual Conference and Exhibition of the British-Cardiovascular-Society, Publisher: B M J PUBLISHING GROUP, Pages: A59-A59, ISSN: 1355-6037
Baksi AJ, Treibel TA, Davies JE, et al., 2010, Changes in the Central Arterial Pressure Pulse With Aging Reply, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 55, Pages: 2183-2184, ISSN: 0735-1097
Wang J-J, Shrive NG, Parker KH, et al., 2010, Wave Propagation and Reflection in the Canine Aorta: Analysis Using a Reservoir-Wave Approach, CANADIAN JOURNAL OF CARDIOLOGY, Vol: 27, ISSN: 0828-282X
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- Citations: 43
Teo S-K, Goryachev AB, Parker KH, et al., 2010, Cellular deformation and intracellular stress propagation during optical stretching, PHYSICAL REVIEW E, Vol: 81, ISSN: 1539-3755
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- Citations: 9
Bowles CT, New SEP, van Loon R, et al., 2010, Hydrodynamic Evaluation of a Bioreactor for Tissue Engineering Heart Valves, Cardiovascular Engineering and Technology, Vol: 1, Pages: 10-17, ISSN: 1869-408X
The principal objective was to develop an autoclavable pulsatile bioreactor capable of subjecting disc-shaped or trileaflet valve tissue constructs to prescribed, reproducible hydrodynamic profiles. The pump actuator consisted of: a computer-controlled stepper motor and a lead-screw attached to the piston of a water filled cylinder which was connected to the outer chamber of a pulsatile sac ventricular assist device with tilting disc valves. Reciprocation of the piston caused circulation of tissue culture medium in a bioreactor comprising a vented low-pressure reservoir and a sealed windkessel (air spring) and flow resistor to simulate arterial compliance and systemic vascular resistance, respectively. Disc-shaped tissue constructs could be interposed between the windkessel and the reservoir to allow them to be subjected to controllable pressure waveforms. Alternatively, the outflow valve of the pulsatile pump could be replaced with a valve-like tissue construct. Evaluation of the hydrodynamic capabilities of the system showed that for both the disc-shaped and the valve constructs a wide range of stable hydrodynamic profiles could be specified and attained, free of pressure transients and valve closure-associated pressure oscillations. Pressure rise within the windkessel was primarily determined by pump driving parameters whereas the time constant of the decay of pressure was determined by the product of windkessel compliance (C) and outflow resistance (R) of the windkessel. In conclusion, the novel bioreactor has a number of characteristics which may be valuable for the development of tissue engineered heart valves. © 2010 Biomedical Engineering Society.
Davies JE, Baksi J, Francis DP, et al., 2010, The arterial reservoir pressure increases with aging and is the major determinant of the aortic augmentation index, AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, Vol: 298, Pages: H580-H586, ISSN: 0363-6135
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- Citations: 125
Alastruey J, Sherwin SJ, Parker KH, et al., 2010, Reply to 'Cord clamp insult may predispose to SIDS', EARLY HUMAN DEVELOPMENT, Vol: 86, Pages: 67-67, ISSN: 0378-3782
Ng J, Clay ST, Barman SA, et al., 2010, Maximum likelihood estimation of vessel parameters from scale space analysis, IMAGE AND VISION COMPUTING, Vol: 28, Pages: 55-63, ISSN: 0262-8856
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- Citations: 43
Setchi AT, Siggers JH, Parker KH, et al., 2010, Mathematical Modeling of Two-Dimensional Flow through Patent Ductus Arteriosus in an Adult, 6th World Congress of Biomechanics (WCB 2010), Publisher: SPRINGER, Pages: 386-+, ISSN: 1680-0737
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- Citations: 2
Davies JE, Francis DP, Hadjiloizou N, et al., 2010, Augmentation of Coronary Blood Flow in Systole by Reflected Waves in the Proximal Aorta, 11th International Congress of the IUPESM/World Congress on Medical Physics and Biomedical Engineering, Publisher: SPRINGER, Pages: 61-64, ISSN: 1680-0737
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- Citations: 1
Patel BA, Arundell M, Parker KH, et al., 2010, Microelectrode investigation of neuroneal ageing from a single identified neurone, PHYSICAL CHEMISTRY CHEMICAL PHYSICS, Vol: 12, Pages: 10065-10072, ISSN: 1463-9076
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- Citations: 16
Witt NC, Chapman N, Thom S, et al., 2010, A novel measure to characterise optimality of diameter relationships at retinal vascular bifurcations, Artery Research, Vol: 4, Pages: 75-80, ISSN: 1872-9312
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