I am an Honorary Clinical Senior Lecturer in Anaesthesia and Intensive Care in the Section of Anaesthetics, Pain Medicine and Intensive Care at Imperial College. I am also a consultant in Anaesthetics and Critical Care at the Royal Marsden NHS Foundation Trust.
My main research interests include the mechanisms lung injury, and the role of immune dysfunction in sepsis and inflammation.
I was awarded my PhD in 2016, for which I received a Wellcome Clinical Research Fellowship through Imperial College, and thereafter appointed as an NIHR Academic Clinical Lecturer, during which time I gained a Masters in Genomics.
et al., 2020, The National Institute for Health Research Critical Care Research Priority Setting Survey 2018, Journal of the Intensive Care Society, Vol:21, ISSN:1751-1437, Pages:198-201
et al., 2020, Monocytes mediate homing of circulating microvesicles to the pulmonaryvasculature during low-grade systemic inflammation, Journal of Extracellular Vesicles, Vol:9, ISSN:2001-3078, Pages:1-16
et al., 2018, Intravascular donor monocytes play a central role in lung transplant ischaemia-reperfusion injury, Thorax, Vol:73, ISSN:1468-3296, Pages:350-360
et al., 2017, An analysis of the delivery of anaesthetic training sessions in the United Kingdom., Anaesthesia, Vol:72, ISSN:0003-2409, Pages:1327-1333
et al., 2017, Pain Assessment in INTensive care (PAINT): an observational study of physician-documented pain assessment in 45 intensive care units in the United Kingdom, Anaesthesia, Vol:72, ISSN:1365-2044, Pages:737-748
et al., 2015, In vivo compartmental analysis of leukocytes in mouse lungs, American Journal of Physiology-lung Cellular and Molecular Physiology, Vol:309, ISSN:1522-1504, Pages:L639-L652
et al., 2015, The role of ex vivo lung perfusion in lung transplantation., J Intensive Care Soc, Vol:16, ISSN:1751-1437, Pages:58-63
Tatham KC, Patel KP, 2014, Suitability of common drugs for patients who avoid animal products, British Medical Journal, Vol:4
et al., 2014, Volutrauma, but not Atelectrauma, Induces Systemic Cytokine Production by Lung-Marginated Monocytes, Critical Care Medicine, Vol:42, ISSN:0090-3493, Pages:e49-e57
et al., 2013, Marginated monocytes play a central role in lung ischaemia-reperfusion injury in mice: Implications for lung transplantation, European Respiratory Journal, Vol:42, ISSN:0903-1936
et al., 2013, Neutrophil-Dependent Shedding Of Heparan Sulfate From The Pulmonary Endothelium In An In Vitro Model Of Simulated Ischemia, American Journal of Respiratory and Critical Care Medicine, Vol:187
et al., 2011, Regulation of monocyte subset proinflammatory responses within the lung microvasculature by the p38 MAPK/MK2 pathway, American Journal of Physiology - Lung Cellular and Molecular Physiology, Vol:301, ISSN:1040-0605, Pages:L812-L821
Tatham KC, 2006, Reduce morbidity by balancing your fluids., British Journal of Hospital Medicine, Vol:4
Tatham K, Patel K, 2009, Complete OSCE Skills for Medical and Surgical Finals, Hodder Arnold, ISBN:9780340974247
et al., 2015, Supranormal Elevation of Systemic Oxygen Delivery in Critically Ill Patients, Reducing Mortality in Critically Ill Patients, Editor(s): Landoni, Muccetti, Zangrillo, Bellomo, Springer, Pages:93-102
et al., 2016, Retention And Activation Of Donor Vascular Monocytes In Transplanted Lungs Suggests A Central Role In Primary Graft Dysfunction, International Conference of the American-Thoracic-Society (ATS), AMER THORACIC SOC, ISSN:1073-449X
Tatham KC, Laycock H, Wordsworth H, 2016, Pain Assessment In Cardiothoracic Intensive Care Units: A Snapshot Audit Of Practice In London Intensive Care Units, International Conference of the American-Thoracic-Society (ATS), AMER THORACIC SOC, ISSN:1073-449X
et al., 2015, In Vivo Compartmental Labeling of the Mouse Lung, American Thoracic Society, ATS Journals, Pages:A3926-A3926, ISSN:1073-449X
et al., 2014, Subclinical endotoxaemia enhances lung ischaemia-reperfusion injury, Winter Meeting of the Anaesthetic-Research-Society (ARS), OXFORD UNIV PRESS, Pages:184P-185P, ISSN:0007-0912
et al., 2013, High-stretch, but not atelectasis, causes systemic cytokine release by lung-marginated monocytes, EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN:0903-1936