Imperial College London
Alternate

DrKostasTsilidis

Faculty of Medicine, School of Public Health

Reader in Cancer Epidemiology and Prevention
 
 
 
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Contact

 

+44 (0)20 7594 2623k.tsilidis

 
 
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Location

 

Praed StreetSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Koureas:2022:10.3390/diagnostics12020295,
author = {Koureas, M and Bogogiannidou, Z and Vontas, A and Kyritsi, MA and Mouchtouri, VA and Dadouli, K and Anagnostopoulos, L and Mina, P and Matziri, A and Ntouska, M and Tsigaridaki, M and Gkiata, V and Tsilidis, KK and Ntzani, EE and Prezerakos, P and Tsiodras, S and Speletas, M and Hadjichristodoulou, C},
doi = {10.3390/diagnostics12020295},
journal = {Diagnostics (Basel)},
title = {SARS-CoV-2 sero-surveillance in Greece: evolution over time and epidemiological attributes during the pre-vaccination pandemic era},
url = {http://dx.doi.org/10.3390/diagnostics12020295},
volume = {12},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BACKGROUND: Nation-wide SARS-CoV-2 seroprevalence surveys provide valuable insights into the course of the pandemic, including information often not captured by routine surveillance of reported cases. METHODS: A serosurvey of IgG antibodies against SARS-CoV-2 was conducted in Greece between March and December 2020. It was designed as a cross-sectional survey repeated at monthly intervals. The leftover sampling methodology was used and a geographically stratified sampling plan was applied. RESULTS: Of 55,947 serum samples collected, 705 (1.26%) were found positive for anti-SARS-CoV-2 antibodies, with higher seroprevalence (9.09%) observed in December 2020. Highest seropositivity levels were observed in the "0-29" and "30-49" year age groups. Seroprevalence increased with age in the "0-29" age group. Highly populated metropolitan areas were characterized with elevated seroprevalence levels (11.92% in Attica, 12.76% in Thessaloniki) compared to the rest of the country (5.90%). The infection fatality rate (IFR) was estimated at 0.451% (95% CI: 0.382-0.549%) using aggregate data until December 2020, and the ratio of actual to reported cases was 9.59 (7.88-11.33). CONCLUSIONS: The evolution of seroprevalence estimates aligned with the course of the pandemic and varied widely by region and age group. Young and middle-aged adults appeared to be drivers of the pandemic during a severe epidemic wave under strict policy measures.
AU  - Koureas,M
AU  - Bogogiannidou,Z
AU  - Vontas,A
AU  - Kyritsi,MA
AU  - Mouchtouri,VA
AU  - Dadouli,K
AU  - Anagnostopoulos,L
AU  - Mina,P
AU  - Matziri,A
AU  - Ntouska,M
AU  - Tsigaridaki,M
AU  - Gkiata,V
AU  - Tsilidis,KK
AU  - Ntzani,EE
AU  - Prezerakos,P
AU  - Tsiodras,S
AU  - Speletas,M
AU  - Hadjichristodoulou,C
DO  - 10.3390/diagnostics12020295
PY  - 2022///
SN  - 2075-4418
TI  - SARS-CoV-2 sero-surveillance in Greece: evolution over time and epidemiological attributes during the pre-vaccination pandemic era
T2  - Diagnostics (Basel)
UR  - http://dx.doi.org/10.3390/diagnostics12020295
UR  - https://www.ncbi.nlm.nih.gov/pubmed/35204386
UR  - http://hdl.handle.net/10044/1/95388
VL  - 12
ER  -
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