Imperial College London

Dr Katharina Anna Wilmes

Faculty of EngineeringDepartment of Bioengineering

Visiting Researcher







4.28Royal School of MinesSouth Kensington Campus





I am a postdoc in the Clopath Lab. I am funded by a research fellowship from the Deutsche Forschungsgemeinschaft (DFG, German Research Foundation).

Our capacity for learning and memory is very dependent on the context we are in. I want to understand the cellular and circuit mechanisms that underlie the regulation of learning in the brain. I am especially interested in the role that interneuron circuits play during learning. In my current research, I am investigating the interaction of interneurons with principal neurons in functional microcircuits and how synaptic plasticity and stimulus processing are modulated during learning.

During my PhD, I studied how dendritic inhibition can gate excitatory plasticity in a switch-like manner by targeting dendritic signals. I did my PhD under the supervision of Susanne Schreiber at the Institute for Theoretical Biology, Humboldt University of Berlin and the Bernstein Center for Computational Neuroscience in Berlin. Prior to that, I studied Cognitive Science (BSc) at Osnabrück University, and Brain and Cognitive Sciences (MSc) at the University of Amsterdam.

I am the postdoc representative of the Bernstein Network Computational Neuroscience



Wilmes KA, Clopath C, 2019, Inhibitory microcircuits for top-down plasticity of sensory representations, Nature Communications, Vol:10, ISSN:2041-1723

Bono J, Wilmes K, Clopath C, 2017, Modelling plasticity in dendrites: from single cells to networks, Current Opinion in Neurobiology, Vol:46, ISSN:0959-4388, Pages:136-141

Wilmes KA, Schleimer J-H, Schreiber S, 2016, Spike-timing dependent inhibitory plasticity to learn a selective gating of backpropagating action potentials, European Journal of Neuroscience, Vol:45, ISSN:0953-816X, Pages:1032-1043

Wilmes KA, Sprekeler H, Schreiber S, 2016, Inhibition as a Binary Switch for Excitatory Plasticity in Pyramidal Neurons, Plos Computational Biology, Vol:12, Pages:e1004768-e1004768

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