The group’s research interests cover a range of topics including eukaryotic protein folding and single molecule approaches to protein dynamics and protein counting. Everything we do involves interdisciplinary approaches to biological research problems – we collaborate with physicists, mathematicians and engineers across Imperial College.
We were founder members of the Centre for Doctoral Training in Chemical Biology and the Institute of Chemical Biology. The EPSRC-funded CDT started life in 2003 and was recently renewed for a 4th round of student intake from 2019-2024. In the first three CDT programmes we trained around 150 PhDs in Chemical Biology subjects ranging from optics, spectroscopies, microfluidics and other physical science-based platforms to biological problems such as artificial vesicles/cells and cancer drug discovery.
et al., 2022, The malaria parasite chaperonin containing TCP-1 (CCT) complex: Data integration with other CCT proteomes, Frontiers in Molecular Biosciences, Vol:9
et al., 2022, Towards high throughput oligomer detection and classification for early-stage aggregation of amyloidogenic protein, Frontiers in Chemistry, Vol:10, ISSN:2296-2646
et al., 2021, Front Cover: Acetylation Rather than H50Q Mutation Impacts the Kinetics of Cu(II) Binding to α‐Synuclein (ChemPhysChem 23/2021), Chemphyschem, Vol:22, ISSN:1439-4235, Pages:2378-2378
et al., 2021, Acetylation rather than H50Q mutation impacts the kinetics of Cu(II) binding to α-synuclein, Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry, Vol:22, ISSN:1439-4235, Pages:2413-2419
et al., 2022, Novel Single Cell Analysis of microRNA Levels in Response to Oxidative Stress and in COPD Using Microfluidic Technology, International Conference of the American-Thoracic-Society, AMER THORACIC SOC, ISSN:1073-449X