Summary
The group’s research interests cover a range of topics including eukaryotic protein folding and single molecule approaches to protein dynamics and protein counting. Everything we do involves interdisciplinary approaches to biological research problems – we collaborate with physicists, mathematicians and engineers across Imperial College.
We were founder members of the Centre for Doctoral Training in Chemical Biology and the Institute of Chemical Biology. The EPSRC-funded CDT started life in 2003 and was recently renewed for a 4th round of student intake from 2019-2024. In the first three CDT programmes we trained around 150 PhDs in Chemical Biology subjects ranging from optics, spectroscopies, microfluidics and other physical science-based platforms to biological problems such as artificial vesicles/cells and cancer drug discovery.
Publications
Journals
Teng X, Sheveleva A, Tuna F, et al., 2021, Front Cover: Acetylation Rather than H50Q Mutation Impacts the Kinetics of Cu(II) Binding to α‐Synuclein (ChemPhysChem 23/2021), Chemphyschem, Vol:22, ISSN:1439-4235, Pages:2378-2378
Ying L, Teng X, Sheveleva A, et al., 2021, Acetylation rather than H50Q mutation impacts the kinetics of Cu(II) binding to α-synuclein, Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry, Vol:22, ISSN:1439-4235, Pages:2413-2419
Teng X, Sheveleva A, Tuna F, et al., 2021, Acetylation Rather than H50Q Mutation Impacts the Kinetics of Cu(II) Binding to alpha-Synuclein, Chemphyschem, ISSN:1439-4235
Klug D, Osman S, Bendtsen C, et al., 2021, Evaluation of FOXO1 target engagement using a single-cell microfluidic platform, Analytical Chemistry, Vol:93, ISSN:0003-2700, Pages:14659-14666
Conference
Ho V, Baker JR, Willison KR, et al., 2022, Novel Single Cell Analysis of microRNA Levels in Response to Oxidative Stress and in COPD Using Microfluidic Technology, AMER THORACIC SOC, ISSN:1073-449X