The group’s research interests cover a range of topics including eukaryotic protein folding and single molecule approaches to protein dynamics and protein counting. Everything we do involves interdisciplinary approaches to biological research problems – we collaborate with physicists, mathematicians and engineers across Imperial College.
We were founder members of the Centre for Doctoral Training in Chemical Biology and the Institute of Chemical Biology. The EPSRC-funded CDT started life in 2003 and was recently renewed for a 4th round of student intake from 2019-2024. In the first three CDT programmes we trained around 150 PhDs in Chemical Biology subjects ranging from optics, spectroscopies, microfluidics and other physical science-based platforms to biological problems such as artificial vesicles/cells and cancer drug discovery.
et al., 2023, Single cell quantification of microRNA from small numbers of non-invasively sampled primary human cells, Communications Biology, Vol:6, ISSN:2399-3642, Pages:1-11
et al., 2022, The malaria parasite chaperonin containing TCP-1 (CCT) complex: Data integration with other CCT proteomes, Frontiers in Molecular Biosciences, Vol:9
et al., 2022, Towards high throughput oligomer detection and classification for early-stage aggregation of amyloidogenic protein, Frontiers in Chemistry, Vol:10, ISSN:2296-2646
et al., 2022, An amplification-free, innovative, multiplex assay to quantify microRNAs in single cells from COPD patients, EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN:0903-1936
et al., 2022, Novel Single Cell Analysis of microRNA Levels in Response to Oxidative Stress and in COPD Using Microfluidic Technology, International Conference of the American-Thoracic-Society, AMER THORACIC SOC, ISSN:1073-449X