Imperial College London


Faculty of Natural SciencesDepartment of Chemistry

Chair in Chemical Biology



+44 (0)20 7594 5837keith.willison Website CV




301FMolecular Sciences Research HubWhite City Campus





The group’s research interests cover a range of topics including eukaryotic protein folding and single molecule approaches to protein dynamics and protein counting. Everything we do involves interdisciplinary approaches to biological research problems – we collaborate with physicists, mathematicians and engineers across Imperial College.

We were founder members of the  Centre for Doctoral Training in Chemical Biology and the Institute of Chemical Biology. The EPSRC-funded CDT started life in 2003 and was recently renewed for a 4th round of student intake from 2019-2024. In the first three CDT programmes we trained around 150 PhDs in Chemical Biology subjects ranging from optics, spectroscopies, microfluidics and other physical science-based platforms to biological problems such as artificial vesicles/cells and cancer drug discovery.



Ying L, Tahirbegi IB, Magness A, et al., 2022, Towards high throughput oligomer detection and classification for early-stage aggregation of amyloidogenic protein, Frontiers in Chemistry, ISSN:2296-2646

Teng X, Sheveleva A, Tuna F, et al., 2021, Front Cover: Acetylation Rather than H50Q Mutation Impacts the Kinetics of Cu(II) Binding to α‐Synuclein (ChemPhysChem 23/2021), Chemphyschem, Vol:22, ISSN:1439-4235, Pages:2378-2378

Ying L, Teng X, Sheveleva A, et al., 2021, Acetylation rather than H50Q mutation impacts the kinetics of Cu(II) binding to α-synuclein, Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry, Vol:22, ISSN:1439-4235, Pages:2413-2419

Teng X, Sheveleva A, Tuna F, et al., 2021, Acetylation Rather than H50Q Mutation Impacts the Kinetics of Cu(II) Binding to alpha-Synuclein, Chemphyschem, ISSN:1439-4235


Ho V, Baker JR, Willison KR, et al., 2022, Novel Single Cell Analysis of microRNA Levels in Response to Oxidative Stress and in COPD Using Microfluidic Technology, AMER THORACIC SOC, ISSN:1073-449X

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