Summary
The group’s research interests cover a range of topics including eukaryotic protein folding and single molecule approaches to protein dynamics and protein counting. Everything we do involves interdisciplinary approaches to biological research problems – we collaborate with physicists, mathematicians and engineers across Imperial College.
We were founder members of the Centre for Doctoral Training in Chemical Biology and the Institute of Chemical Biology. The EPSRC-funded CDT started life in 2003 and was recently renewed for a 4th round of student intake from 2019-2024. In the first three CDT programmes we trained around 150 PhDs in Chemical Biology subjects ranging from optics, spectroscopies, microfluidics and other physical science-based platforms to biological problems such as artificial vesicles/cells and cancer drug discovery.
Publications
Journals
Teng X, Sheveleva A, Tuna F, et al., 2021, Front Cover: Acetylation Rather than H50Q Mutation Impacts the Kinetics of Cu(II) Binding to α‐Synuclein (ChemPhysChem 23/2021), Chemphyschem, Vol:22, ISSN:1439-4235, Pages:2378-2378
Teng X, Sheveleva A, Tuna F, et al., 2021, Acetylation Rather than H50Q Mutation Impacts the Kinetics of Cu(II) Binding to α-Synuclein., Chemphyschem
Klug D, Osman S, Bendtsen C, et al., 2021, Evaluation of FOXO1 target engagement using a single-cell microfluidic platform, Analytical Chemistry, Vol:93, ISSN:0003-2700, Pages:14659-14666
Ying L, Teng X, Sheveleva A, et al., 2021, Acetylation rather than H50Q mutation impacts the kinetics of Cu(II) binding to α-synuclein, Chemphyschem: a European Journal of Chemical Physics and Physical Chemistry, ISSN:1439-4235
Conference
Teng X, Probing the Interactions of Intrinsically Disordered Protein with Metal Ions and Lipid Membranes by Fluorescence Spectroscopy, 65th Annual Meeting of The Biophysical Society