Imperial College London

ProfessorKeithWillison

Faculty of Natural SciencesDepartment of Chemistry

Chair in Chemical Biology
 
 
 
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Contact

 

+44 (0)20 7594 5837keith.willison Website CV

 
 
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Location

 

301FMolecular Sciences Research HubWhite City Campus

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Summary

 

Publications

Publication Type
Year
to

215 results found

Chapple JP, Grayson C, Willison KR, Hardcastle AJ, Cheetham MEet al., 2001, Delineation of the plasma membrane targeting domain of RP2., Publisher: ASSOC RESEARCH VISION OPHTHALMOLOGY INC, Pages: S653-S653, ISSN: 0146-0404

Conference paper

Kafri G, Willison KR, Horovitz A, 2001, Nested allosteric interactions in the cytoplasmic chaperonin containing TCP-1, PROTEIN SCIENCE, Vol: 10, Pages: 445-449, ISSN: 0961-8368

Journal article

Grantham J, Willison KR, 2000, The use of monoclonal antibodies to study interactions between CCT and its major substrates actin and tubulin., Publisher: AMER SOC CELL BIOLOGY, Pages: 99A-99A, ISSN: 1059-1524

Conference paper

Ritco-Vonsovici M, Willison KR, 2000, Defining the eukaryotic cytosolic chaperonin-binding sites in human tubulins, JOURNAL OF MOLECULAR BIOLOGY, Vol: 304, Pages: 81-98, ISSN: 0022-2836

Journal article

Llorca O, Martín-Benito J, Ritco-Vonsovici M, Grantham J, Hynes GM, Willison KR, Carrascosa JL, Valpuesta JMet al., 2000, Eukaryotic chaperonin CCT stabilizes actin and tubulin folding intermediates in open quasi-native conformations, EMBO JOURNAL, Vol: 19, Pages: 5971-5979, ISSN: 0261-4189

Journal article

Willison KR, Valpuesta JM, Martin-Benito J, Gomez-Puertas P, Carrascosa JLet al., 2000, Structure and function of a protein folding machine: the eukaryotic cytosolic chaperonin CCT, FEBS Letters, Vol: 529, Pages: 11-16

Journal article

Chapple JP, Hardcastle AJ, Grayson C, Spackman LA, Willison KR, Cheetham MEet al., 2000, Mutations in the N-terminus of the X-linked retinitis pigmentosa protein RP2 interfere with the normal targeting of the protein to the plasma membrane, HUMAN MOLECULAR GENETICS, Vol: 9, Pages: 1919-1926, ISSN: 0964-6906

Journal article

Willison KR, 2000, A UK-centric history of studies on the mouse t-complex, International Journal of Developmental Biology, Vol: 44, Pages: 57-63

Journal article

Hynes GM, Willison KR, 2000, Individual subunits of the eukaryotic cytosolic chaperonin mediate interactions with binding sites located on subdomains of β-actin, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 275, Pages: 18985-18994, ISSN: 0021-9258

Journal article

Chapple JP, Hardcastle AJ, Willison KR, Cheetham MEet al., 2000, RP2 protein is ubiquitously expressed in human tissues., Publisher: ASSOC RESEARCH VISION OPHTHALMOLOGY INC, Pages: S879-S879, ISSN: 0146-0404

Conference paper

Grantham J, Llorca O, Valpuesta JM, Willison KRet al., 2000, Partial occlusion of both cavities of the eukaryotic chaperonin with antibody has no effect upon the rates of β-actin or α-tubulin folding, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 275, Pages: 4587-4591, ISSN: 0021-9258

Journal article

Willison KR, Lyon MF, 2000, A UK-centric history of studies on the mouse <i>t</i>-complex, INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY, Vol: 44, Pages: 57-63, ISSN: 0214-6282

Journal article

Llorca O, McCormack EA, Hynes G, Grantham J, Cordell J, Carrascosa JL, Willison KR, Fernandez JJ, Valpuesta JMet al., 1999, Eukaryotic type II chaperonin CCT interacts with actin through specific subunits, NATURE, Vol: 402, Pages: 693-696, ISSN: 0028-0836

Journal article

Willison KR, 1999, Genetics - Distorting sex ratios, NATURE, Vol: 402, Pages: 131-132, ISSN: 0028-0836

Journal article

Willison KR, 1999, Box 1: Sperm sexing and selection, NATURE, Vol: 402, Pages: 132-132, ISSN: 0028-0836

Journal article

Willison KR, 1999, Composition and Function of the Eukaryotic Cytosolic Chaperonin Containing TCP-1, Publisher: Harwood Academic Publishers, Pages: 555-571

Book chapter

Llorca O, Smyth MG, Carrascosa JL, Willison KR, Radermacher M, Steinbacher S, Valpuesta JMet al., 1999, 3D reconstruction of the ATP-bound form of CCT reveals the asymmetric folding conformation of a type II chaperonin, NATURE STRUCTURAL BIOLOGY, Vol: 6, Pages: 639-642, ISSN: 1072-8368

Journal article

Willison KR, 1999, Distorting sex ratios

Other

Willison KR, 1998, Method for identifying compounds binding to the chaperonin CCT

Assay/screening patent which covers variations of the CCT complex together with substrates, fragments and peptides which disrupt function

Patent

Llorca O, Smyth MG, Marco S, Carrascosa JL, Willison KR, Valpuesta JMet al., 1998, ATP binding induces large conformational changes in the apical and equatorial domains of the eukaryotic chaperonin containing TCP-1 complex, JOURNAL OF BIOLOGICAL CHEMISTRY, Vol: 273, Pages: 10091-10094, ISSN: 0021-9258

Journal article

Liou AKF, McCormack EA, Willison KR, 1998, The chaperonin containing TCP-1 (CCT) displays a single-ring mediated disassembly and reassembly cycle, BIOLOGICAL CHEMISTRY, Vol: 379, Pages: 311-319, ISSN: 1431-6730

Journal article

Willison KR, Kubota H, 1997, Cytosolic chaperonins - an overview, Oxford, Publisher: Oxford University Press, Pages: 207-226

Book chapter

Liou AKF, Willison KR, 1997, Elucidation of the subunit orientation in CCT (chaperonin containing TCP1) from the subunit composition of CCT micro-complexes, EMBO JOURNAL, Vol: 16, Pages: 4311-4316, ISSN: 0261-4189

Journal article

Kubota H, Hynes GM, Kerr SM, Willison KRet al., 1997, Tissue-specific subunit of the mouse cytosolic chaperonin-containing TCP-1, FEBS LETTERS, Vol: 402, Pages: 53-56, ISSN: 0014-5793

Journal article

Whatmore J, Morgan CP, Cunningham E, Collison KS, Willison KR, Cockcroft Set al., 1996, ADP-ribosylation factor 1-regulated phospholipase D activity is localized at the plasma membrane and intracellular organelles in HL60 cells, BIOCHEMICAL JOURNAL, Vol: 320, Pages: 785-794, ISSN: 0264-6021

Journal article

Hynes G, Celis JE, Lewis VA, Carne A U S, Lauridsen JB, Willison KRet al., 1996, Analysis of chaperonin-containing TCP-1 subunits in the human keratinocyte two-dimensional protein database: Further characterisation of antibodies to individual subunits, ELECTROPHORESIS, Vol: 17, Pages: 1720-1727, ISSN: 0173-0835

Journal article

Willison KR, 1996, The chaperonin containing TCP-1 (CCT) multisubunit machinery assisting in protein folding and assembly in eukaryotic cytosol, France, Publisher: CNRS

Book chapter

Willison KR, Horwich AL, 1996, Structure and function of chaperonins in archaebacteria and eukaryotic cytosol, New York, Publisher: Academic Press Inc, Pages: 107-136

Book chapter

West AP, Willison KR, 1996, Brefeldin A and mannose 6-phosphate regulation of acrosomic related vesicular trafficking, EUROPEAN JOURNAL OF CELL BIOLOGY, Vol: 70, Pages: 315-321, ISSN: 0171-9335

Journal article

Hynes G, Sutton CW U S, Willison KR, 1996, Peptide mass fingerprinting of chaperonin-containing TCP-1 (CCT) and copurifying proteins, FASEB JOURNAL, Vol: 10, Pages: 137-147, ISSN: 0892-6638

Journal article

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