Publications
565 results found
Bertrand ME, Remme WJ, Fox KM, et al., 2007, Effects of perindopril on long-term clinical outcome of patients with coronary artery disease and preserved left ventricular function, INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol: 121, Pages: 57-61, ISSN: 0167-5273
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- Citations: 12
Brugts JJ, Boersma E, Chonchol M, et al., 2007, The cardioprotective effects of ACE-inhibition by perindopril not modified by renal function in patients with stable coronary artery disease, EUROPEAN HEART JOURNAL, Vol: 28, Pages: 214-214, ISSN: 0195-668X
Fox K, 2007, Contribution of perindopril to cardiology: 20 years of success, Satellite Symposium on Past, Present and Future of ACE Inhibitors, Publisher: OXFORD UNIV PRESS, Pages: E10-E19, ISSN: 1520-765X
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- Citations: 10
Briggs A, Mihaylova B, Sculpher M, et al., 2007, Cost effectiveness of perindopril in reducing cardiovascular events in patients with stable coronary artery disease using data from the EUROPA study, HEART, Vol: 93, Pages: 1081-1086, ISSN: 1355-6037
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- Citations: 46
Mills P, Weber H, Lopez-Senclon J, et al., 2007, Recommendations on sub-speciality accreditation in cardiology, EUROPEAN HEART JOURNAL, Vol: 28, Pages: 2163-2171, ISSN: 0195-668X
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- Citations: 20
Fox K, Borer JS, Camm AJ, et al., 2007, Resting heart rate in cardiovascular disease, JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, Vol: 50, Pages: 823-830, ISSN: 0735-1097
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- Citations: 793
Bots ML, Remme WJ, Luescher TF, et al., 2007, ACE inhibition and endothelial function:: Main findings of PERFECT, a sub-study of the EUROPA trial, CARDIOVASCULAR DRUGS AND THERAPY, Vol: 21, Pages: 269-279, ISSN: 0920-3206
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- Citations: 47
Rodriguez-Granillo GA, Vos J, Bruining N, et al., 2007, Long-term effect of <i>Perindopril</i> on coronary atherosclerosis progression (from the PERindopril's Prospective Effect on Coronary aTherosclerosis by Angiography and IntraVascular ultrasound Evaluation [PERSPECTIVE] study), AMERICAN JOURNAL OF CARDIOLOGY, Vol: 100, Pages: 159-163, ISSN: 0002-9149
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- Citations: 54
Ferrari R, Fox K, Tendera M, et al., 2007, The BEAUTIFUL study: Baseline characteristics of included patients, 19th World Congress of the International-Society-for-Heart-Research, Publisher: ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD, Pages: S160-S160, ISSN: 0022-2828
Lyne J, Fox K, Mohiaddin RH, 2007, Follow up in a case of cardiac contusion using cardiovascular magnetic resonance, JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE, Vol: 9, Pages: 589-589, ISSN: 1097-6647
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- Citations: 4
Agodoa L, Anderson C, Asseibergs F, et al., 2007, Blood pressure-dependent and independent effects of agents that inhibit the renin-angiotensin system, JOURNAL OF HYPERTENSION, Vol: 25, Pages: 951-958, ISSN: 0263-6352
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- Citations: 296
Fox KM, Bertrand ME, Remme WJ, et al., 2007, Efficacy of perindopril in reducing risk of cardiac events in patients with revascularized coronary artery disease, AMERICAN HEART JOURNAL, Vol: 153, Pages: 629-635, ISSN: 0002-8703
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- Citations: 13
Lenzen MJ, Scholte op Reimer WJM, Pedersen SS, et al., 2007, The additional value of patient-reported health status in predicting 1-year mortality after invasive coronary procedures: a report from the Euro Heart Survey on Coronary Revascularisation., Heart, Vol: 93, Pages: 339-344
OBJECTIVE: Self-perceived health status may be helpful in identifying patients at high risk for adverse outcomes. The Euro Heart Survey on Coronary Revascularization (EHS-CR) provided an opportunity to explore whether impaired health status was a predictor of 1-year mortality in patients with coronary artery disease (CAD) undergoing angiographic procedures. METHODS: Data from the EHS-CR that included 5619 patients from 31 member countries of the European Society of Cardiology were used. Inclusion criteria for the current study were completion of a self-report measure of health status, the EuroQol Questionnaire (EQ-5D) at discharge and information on 1-year follow-up, resulting in a study population of 3786 patients. RESULTS: The 1-year mortality was 3.2% (n = 120). Survivors reported fewer problems on the five dimensions of the EQ-5D as compared with non-survivors. A broad range of potential confounders were adjusted for, which reached a p<0.10 in the unadjusted analyses. In the adjusted analyses, problems with self-care (OR 3.45; 95% CI 2.14 to 5.59) and a low rating (< or =60) on health status (OR 2.41; 95% CI 1.47 to 3.94) were the most powerful independent predictors of mortality, among the 22 clinical variables included in the analysis. Furthermore, patients who reported no problems on all five dimensions had significantly lower 1-year mortality rates (OR 0.47; 95% CI 0.28 to 0.81). CONCLUSIONS: This analysis shows that impaired health status is associated with a 2-3-fold increased risk of all-cause mortality in patients with CAD, independent of other conventional risk factors. These results highlight the importance of including patients' subjective experience of their own health status in the evaluation strategy to optimise risk stratification and management in clinical practice.
Bugiardini R, Badimon L, Collins P, et al., 2007, Angina, "normal" coronary angiography, and vascular dysfunction: Risk assessment strategies, PLoS Medicine, Vol: 4, Pages: 0252-0255, ISSN: 1549-1277
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- Citations: 61
Bugiardini R, Badimon L, Collins P, et al., 2007, Angina, "normal" coronary angiography, and vascular dysfunction: Risk assessment strategies, PLOS MEDICINE, Vol: 4, Pages: 252-255, ISSN: 1549-1676
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- Citations: 62
Musto C, Simon P, Nicol E, et al., 2007, 64-multislice computed tomography in consecutive patients with suspected or proven coronary artery disease: Initial single center experience, INTERNATIONAL JOURNAL OF CARDIOLOGY, Vol: 114, Pages: 90-97, ISSN: 0167-5273
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- Citations: 23
Ceconi C, Fox KM, Remme WJ, et al., 2007, ACE inhibition with perindopril and endothelial function. Results of a substudy of the EUROPA study: PERTINENT, CARDIOVASCULAR RESEARCH, Vol: 73, Pages: 237-246, ISSN: 0008-6363
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- Citations: 151
Ruzyllo W, Tendera M, Ford I, et al., 2007, Antianginal efficacy and safety of ivabradine compared with amlodipine in patients with stable effort angina pectoris - A 3-month randomised, double-blind, multicentre, noninferiority trial, DRUGS, Vol: 67, Pages: 393-405, ISSN: 0012-6667
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- Citations: 150
Daly C, DeBacker G, Fox K, 2006, Guidelines on the management of stable angina pectoris: executive summary: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology: reply, EUROPEAN HEART JOURNAL, Vol: 27, Pages: 2903-2903, ISSN: 0195-668X
Lenzen M, Ryden L, Ohrvik J, et al., 2006, Diabetes known or newly detected, but not impaired glucose regulation, has a negative influence on 1-year outcome in patients with coronary artery disease: a report from the Euro Heart Survey on diabetes and the heart., Eur Heart J, Vol: 27, Pages: 2969-2974, ISSN: 0195-668X
AIMS: Although diabetes is known to be a major contributor to cardiovascular diseases, as well as an independent predictor for adverse outcomes in patients with coronary artery disease (CAD), information on the prognosis of patients with CAD and newly diagnosed diabetes or impaired glucose regulation (IGR) is scarce. The objective of this study was to explore 1-year outcome in relation to different glucometabolic states of patients participating in the Euro Heart Survey on diabetes and the heart. METHODS AND RESULTS: In 4676 out of 4961 patients, information on the relation between 1-year outcome and glucometabolic state, which was based on oral glucose tolerance test (OGTT) or fasting glucose plasma, was available. A normal glucose metabolism was identified in 947 patients, IGR (impaired fasting glucose or impaired glucose tolerance) in 1116 patients, and diabetes in 1877 patients of whom 1425 were previously diagnosed and 452 newly diagnosed. In total, 736 patients could not be classified, as no OGTT or fasting plasma glucose was performed. Previously recognized and newly detected diabetes was associated with an increased risk of 1-year mortality when compared with patients with normal glucose regulation [hazard ratio (HR) 2.4, 95% confidence interval (CI) 1.5-3.8 and HR 2.0, 95% CI 1.1-3.6, respectively)]. IGR, however, could not be identified as an independent predictor for 1-year mortality (HR 1.1, 95% CI 0.6-1.9). CONCLUSION: This study confirmed that patients with CAD and known diabetes are at high risk for mortality and cardiovascular events and demonstrated that patients with newly diagnosed diabetes are at intermediate risk for adverse outcomes. IGR, however, could not be identified as an independent predictor for adverse outcomes during the 1-year follow-up period.
Fox K, Ferrari R, Tendera M, et al., 2006, Rationale and design of a randomized, double-blind, placebo-controlled trial of ivabradine in patients with stable coronary artery disease and left ventricular systolic dysfunction:: the morBidity-mortality EvAlUaTion of the I<sub>f</sub> inhibitor ivabradine in patients with coronary disease and left ventricULar dysfunction (BEAUTIFUL) Study, AMERICAN HEART JOURNAL, Vol: 152, Pages: 860-866, ISSN: 0002-8703
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- Citations: 71
Fox K, Daly C, 2006, Guidelines on the management of stable angina pectoris: Reply, EUROPEAN HEART JOURNAL, Vol: 27, Pages: 2606-2607, ISSN: 0195-668X
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- Citations: 1
Tendera M, Fox K, Tardif JC, et al., 2006, Anti-ischemic and antianginal efficacy of ivabradine, a selective and specific I<sub>I</sub> current inhibitor, in elderly patients with stable angina, 79th Annual Scientific Session of the American-Heart-Association, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 715-715, ISSN: 0009-7322
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- Citations: 2
Poole-Wilson PA, Pocock SJ, Fox KAA, et al., 2006, Interventional versus conservative treatment in acute non-ST elevation coronary syndrome: time course of patient management and disease events over one year in the RITA 3 trial, HEART, Vol: 92, Pages: 1473-1479, ISSN: 1355-6037
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- Citations: 16
Fox K, Alonso Garcia MA, Ardissino D, et al., 2006, Guidelines on the management of stable angina pectoris:: Executive summary, REVISTA ESPANOLA DE CARDIOLOGIA, Vol: 59, Pages: 919-970, ISSN: 1885-5857
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- Citations: 17
Fox K, Ferrari R, Yusuf S, et al., 2006, Should angiotensin-converting enzyme-inhibitors be used to improve outcome in patients with coronary artery disease and 'preserved' left ventricular function?, EUROPEAN HEART JOURNAL, Vol: 27, Pages: 2154-2157, ISSN: 0195-668X
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- Citations: 11
Dagenais GR, Pogue J, Fox K, et al., 2006, Angiotensin-converting-enzyme inhibitors in stable vascular disease without left ventricular systolic dysfunction or heart failure: a combined analysis of three trials, LANCET, Vol: 368, Pages: 581-588, ISSN: 0140-6736
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- Citations: 381
Fox K, Garcia MAA, Ardissino D, et al., 2006, [Guidelines on the management of stable angina pectoris; the experts of the European Society of Cardiology on the management of stable angina pectoris]., Kardiol Pol, Vol: 64, Pages: 823-880, ISSN: 0022-9032
Daly C, Clemens F, Lopez-Sendon JL, et al., 2006, The impact of guideline compliant medical therapy on clinical outcome in patients with stable angina: findings from the Euro Heart Survey of stable angina, EUROPEAN HEART JOURNAL, Vol: 27, Pages: 1298-1304, ISSN: 0195-668X
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- Citations: 41
Fox K, Angeles Alonso Garcia M, Ardissino D, et al., 2006, Guidelines on the management of stable angina pectoris: executive summary, EUROPEAN HEART JOURNAL, Vol: 27, Pages: 1341-1381, ISSN: 0195-668X
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- Citations: 1051
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