Imperial College London
Alternate

DrKirillVeselkov

Faculty of Medicine, Department of Surgery & Cancer

Lecturer
 
 
 
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Contact

 

+44 (0)20 7594 3899kirill.veselkov04

 
 
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Location

 

Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Lowe:2019:10.1097/MPA.0000000000001412,
author = {Lowe, ME and Andersen, DK and Caprioli, RM and Choudhary, J and Cruz-Monserrate, Z and Dasyam, AK and Forsmark, CE and Gorelick, FS and Gray, JW and Haupt, M and Kelly, KA and Olive, KP and Plevritis, SK and Rappaport, N and Roth, HR and Steen, H and Swamidass, SJ and Tirkes, T and Uc, A and Veselkov, K and Whitcomb, DC and Habtezion, A},
doi = {10.1097/MPA.0000000000001412},
journal = {Pancreas},
pages = {1250--1258},
title = {Precision medicine in pancreatic disease-knowledge gaps and research opportunities: Summary of a national institute of diabetes and digestive and kidney diseases workshop},
url = {http://dx.doi.org/10.1097/MPA.0000000000001412},
volume = {48},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - A workshop on research gaps and opportunities for Precision Medicine in Pancreatic Disease was sponsored by the National Institute of Diabetes and Digestive Kidney Diseases on July 24, 2019, in Pittsburgh. The workshop included an overview lecture on precision medicine in cancer and 4 sessions: (1) general considerations for the application of bioinformatics and artificial intelligence; (2) omics, the combination of risk factors and biomarkers; (3) precision imaging; and (4) gaps, barriers, and needs to move from precision to personalized medicine for pancreatic disease. Current precision medicine approaches and tools were reviewed, and participants identified knowledge gaps and research needs that hinder bringing precision medicine to pancreatic diseases. Most critical were (a) multicenter efforts to collect large-scale patient data sets from multiple data streams in the context of environmental and social factors; (b) new information systems that can collect, annotate, and quantify data to inform disease mechanisms; (c) novel prospective clinical trial designs to test and improve therapies; and (d) a framework for measuring and assessing the value of proposed approaches to the health care system. With these advances, precision medicine can identify patients early in the course of their pancreatic disease and prevent progression to chronic or fatal illness.
AU  - Lowe,ME
AU  - Andersen,DK
AU  - Caprioli,RM
AU  - Choudhary,J
AU  - Cruz-Monserrate,Z
AU  - Dasyam,AK
AU  - Forsmark,CE
AU  - Gorelick,FS
AU  - Gray,JW
AU  - Haupt,M
AU  - Kelly,KA
AU  - Olive,KP
AU  - Plevritis,SK
AU  - Rappaport,N
AU  - Roth,HR
AU  - Steen,H
AU  - Swamidass,SJ
AU  - Tirkes,T
AU  - Uc,A
AU  - Veselkov,K
AU  - Whitcomb,DC
AU  - Habtezion,A
DO  - 10.1097/MPA.0000000000001412
EP  - 1258
PY  - 2019///
SN  - 0885-3177
SP  - 1250
TI  - Precision medicine in pancreatic disease-knowledge gaps and research opportunities: Summary of a national institute of diabetes and digestive and kidney diseases workshop
T2  - Pancreas
UR  - http://dx.doi.org/10.1097/MPA.0000000000001412
UR  - https://www.ncbi.nlm.nih.gov/pubmed/31688587
UR  - http://hdl.handle.net/10044/1/74927
VL  - 48
ER  -
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