Imperial College London
Alternate

DrKirillVeselkov

Faculty of Medicine, Department of Surgery & Cancer

Lecturer
 
 
 
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Contact

 

+44 (0)20 7594 3899kirill.veselkov04

 
 
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Location

 

Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Giallourou:2020:10.1126/sciadv.aay5969,
author = {Giallourou, N and Fardus-Reid, F and Panic, G and Veselkov, K and McCormick, BJJ and Olortegui, MP and Ahmed, T and Mduma, E and Yori, PP and Mahfuz, M and Svensen, E and Ahmed, MMM and Colston, JM and Kosek, MN and Swann, JR},
doi = {10.1126/sciadv.aay5969},
journal = {Science Advances},
pages = {1--10},
title = {Metabolic maturation in the first 2 years of life in resource-constrained settings and its association with postnatal growths},
url = {http://dx.doi.org/10.1126/sciadv.aay5969},
volume = {6},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Malnutrition continues to affect the growth and development of millions of children worldwide, and chronic undernutrition has proven to be largely refractory to interventions. Improved understanding of metabolic development in infancy and how it differs in growth-constrained children may provide insights to inform more timely, targeted, and effective interventions. Here, the metabolome of healthy infants was compared to that of growth-constrained infants from three continents over the first 2 years of life to identify metabolic signatures of aging. Predictive models demonstrated that growth-constrained children lag in their metabolic maturity relative to their healthier peers and that metabolic maturity can predict growth 6 months into the future. Our results provide a metabolic framework from which future nutritional programs may be more precisely constructed and evaluated.
AU  - Giallourou,N
AU  - Fardus-Reid,F
AU  - Panic,G
AU  - Veselkov,K
AU  - McCormick,BJJ
AU  - Olortegui,MP
AU  - Ahmed,T
AU  - Mduma,E
AU  - Yori,PP
AU  - Mahfuz,M
AU  - Svensen,E
AU  - Ahmed,MMM
AU  - Colston,JM
AU  - Kosek,MN
AU  - Swann,JR
DO  - 10.1126/sciadv.aay5969
EP  - 10
PY  - 2020///
SN  - 2375-2548
SP  - 1
TI  - Metabolic maturation in the first 2 years of life in resource-constrained settings and its association with postnatal growths
T2  - Science Advances
UR  - http://dx.doi.org/10.1126/sciadv.aay5969
UR  - https://advances.sciencemag.org/content/6/15/eaay5969
UR  - http://hdl.handle.net/10044/1/77979
VL  - 6
ER  -
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