Imperial College London

DrKirkTaylor

Faculty of MedicineNational Heart & Lung Institute

Honorary Research Associate
 
 
 
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Contact

 

kirk.taylor Website

 
 
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Location

 

Desk 7Sir Alexander Fleming BuildingSouth Kensington Campus

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Summary

 

Overview

Publications


2019

13- Taylor KA & Mahaut-Smith MP (2019). Whole cell recordings of megakaryocyte Ca2 activated currents sensitive to the TMEM16F inhibitor CaCCinh-A01 reveal an interspecies difference in ionic selectivity. Platelets. 22:1-5 DOI: 10.1080/09537104.2019.1595560 

12- Taylor KA, Smyth E, Rauzi F, Cerrone M, Khawaja AA, Gazzard B, Nelson M, Boffito M & Emerson M (2019). Pharmacological impact of antiretroviral therapy on platelet function to investigate human immunodeficiency virus-associated cardiovascular risk. Br J Pharmacol. 176(7):879-889. https://doi.org/10.1111/bph.14589

11- Ahmed NS, Lopes Pires M, Taylor KA & Pugh N (2019). Agonist-Evoked Increases in Intra-Platelet Zinc Couple to Functional Responses. Thromb. Haemost. DOI: 10.1055/s-0038-1676589

2018

10- Taylor KA & Emerson M (2018). Refinement of a mouse cardiovascular model: Development, application and dissemination. F1000 Research doi:10.12688/f1000research.14456.1. eCollection 2018.

9- Gillespie S, Holloway PM, Becker F, Rauzi F, Vital SA, Taylor KA, Stokes KY, Emerson M & Gavins FNE (2018). The isothiocyanate sulforaphane modulates platelet function and protects against cerebral thrombotic dysfunction. Br J Pharmacol doi:10.1111/bph.14368

2017

8- Taylor KA, Wilson DGS, Harper MT, & Pugh, N (2017). Extracellular chloride is required for efficient platelet aggregation. Platelets, 1-5. doi:10.1080/09537104.2017.1332367

7- Pugh N, Maddox BD, Bihan D, Taylor KA, Mahaut-Smith MP, & Farndale RW (2017). Differential integrin activity mediated by platelet collagen receptor engagement under flow conditions. Thromb. Haemost. doi:10.1160/TH16-12-0906

2016

6- Mahaut-Smith MP, Taylor KA & Evans RJ (2016). Calcium Signalling through Ligand-Gated Ion Channels such as P2X1 Receptors in the Platelet and other Non-Excitable Cells. In J. A. Rosado (Ed.), Calcium Entry Pathways in Non-excitable Cells (Vol. 898, pp. 305-329). Advances in Experimental Medicine. doi:10.1007/978-3-319-26974-0_13

5- Osman S, Taylor KA, Allcock N, Rainbow RD, & Mahaut-Smith MP (2016). Detachment of surface membrane invagination systems by cationic amphiphilic drugs. SCIENTIFIC REPORTS, 6, 13 pages. doi:10.1038/srep18536

4- Taylor KA, & Pugh N (2016). The contribution of zinc to platelet behaviour during haemostasis and thrombosis. METALLOMICS, 8(2), 144-155. doi:10.1039/c5mt00251f

3- Watson BR, White NA, Taylor KA, Howes J-M, Malcor J-DM, Bihan D, Sage SO, Farndale RW & Pugh, N. (2016). Zinc is a transmembrane agonist that induces platelet activation in a tyrosine phosphorylation-dependent manner. METALLOMICS, 8(1), 91-100. doi:10.1039/c5mt00064e

2015

2- Taylor KA, Wright JR, & Mahaut-Smith MP (2015). Regulation of Pannexin-1 channel activity. BIOCHEMICAL SOCIETY TRANSACTIONS, 43, 502-507. doi:10.1042/BST20150042

2014

1- Taylor KA, Wright JR, Vial C, Evans RJ, & Mahaut-Smith MP (2014). Amplification of human platelet activation by surface pannexin-1 channels. JOURNAL OF THROMBOSIS AND HAEMOSTASIS, 12(6), 987-998. doi:10.1111/jth.12566