Summary
I use mathematical modelling and statistics to answer practical questions about vaccine impacts, infectious disease transmission, and outbreak response to help improve public health in resource-limited settings. I have worked on a variety of vaccine-preventable infectious diseases, primarily bacterial meningitis and polio.
I am currently working on the epidemiology of vaccine-derived polioviruses as a research associate in the Vaccine Epidemiology Research Group with Dr. Isobel Blake and Dr. Nick Grassly.
Listen to my colleague Dr. Sam Okiror and myself talking about how population immunity to polio has changed since 2016 and how to better respond to vaccine-derived polio outbreaks in Africa. Link here
Selected Publications
Journal Articles
Cooper LV, Erbeto TB, Danzomo AA, et al., 2024, Effectiveness of poliovirus vaccines against circulating vaccine-derived type 2 poliomyelitis in Nigeria between 2017 and 2022: a case-control study, Lancet Infectious Diseases, Vol:24, ISSN:1473-3099, Pages:427-436
Cooper LV, Blake IM, 2024, First Africa-based clinical trial for novel type 2 oral poliovirus vaccine., Lancet, Vol:403, Pages:1113-1115
Bandyopadhyay AS, Lopez Cavestany R, Blake IM, et al., 2023, Use of inactivated poliovirus vaccine for poliovirus outbreak response., Lancet Infect Dis
Gray E, Cooper L, Bandyopadhyay A, et al., 2023, The origins and risk factors for serotype-2 vaccine-derived poliovirus (VDPV2) emergences in Africa during 2016-2019, Journal of Infectious Diseases, Vol:228, ISSN:0022-1899, Pages:80-88
Shaw A, Cooper L, Gumede N, et al., 2022, Time taken to detect and respond to polio outbreaks in Africa and the potential impact of direct molecular detection and nanopore sequencing, Journal of Infectious Diseases, Vol:226, ISSN:0022-1899, Pages:453-462
Cooper LV, Bandyopadhyay AS, Gumede N, et al., 2022, Risk factors for the spread of vaccine-derived type 2 polioviruses after global withdrawal of trivalent oral poliovirus vaccine and the effects of outbreak responses with monovalent vaccine: a retrospective analysis of surveillance data for 51 countries in Africa, Lancet Infectious Diseases, Vol:22, ISSN:1473-3099, Pages:284-294
Cooper LV, Ronveaux O, Fernandez K, et al., 2019, Spatiotemporal Analysis of Serogroup C Meningococcal Meningitis Spread in Niger and Nigeria and Implications for Epidemic Response, Journal of Infectious Diseases, Vol:220, ISSN:0022-1899, Pages:S244-S252
Cooper LV, Stuart JM, Okot C, et al., 2019, Reactive vaccination as a control strategy for pneumococcal meningitis outbreaks in the African meningitis belt: Analysis of outbreak data from Ghana, Vaccine, Vol:37, ISSN:0264-410X, Pages:5657-5663
Cooper LV, Robson A, Trotter CL, et al., 2019, Risk factors for acquisition of meningococcal carriage in the African meningitis belt, Tropical Medicine & International Health, Vol:24, ISSN:1360-2276, Pages:392-400
Hampson K, Trotter C, 2019, The potential effect of improved provision of rabies post-exposure prophylaxis in Gavi-eligible countries: a modelling study, Lancet Infectious Diseases, Vol:19, ISSN:1473-3099, Pages:102-111
Cooper L, Kristiansen PA, Christensen H, et al., 2019, Meningococcal carriage by age in the African meningitis belt: a systematic review and meta-analysis, Epidemiology and Infection, Vol:147, ISSN:0950-2688