Publications
47 results found
Finney LJ, Belchamber KBR, Mallia P, et al., 2016, HUMAN RHINOVIRUS IMPAIRS THE INNATE IMMUNE RESPONSE TO BACTERIA IN MONOCYTE DERIVED MACROPHAGES FROM PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE, British Thoracic Society Winter Meeting 2016, Publisher: BMJ PUBLISHING GROUP, Pages: A2-A2, ISSN: 0040-6376
Finney LJ, Belchamber KBR, Edwards MR, et al., 2016, Rhinovirus Impairs Phagocytosis Of Bacteria By Monocyte Derived Macrophages In Chronic Obstructive Pulmonary Disease, International Conference of the American-Thoracic-Society (ATS), Publisher: AMER THORACIC SOC, ISSN: 1073-449X
Finney L, Elkin S, Todd S, et al., 2015, LATE-BREAKING ABSTRACT: Microbiology and radiology of pneumonia in COPD, Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN: 0903-1936
Coleman M, Finney LJ, Komrower D, et al., 2015, Markers to differentiate between Kaposi's sarcoma and tuberculous pleural effusions in HIV-positive patients, INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Vol: 19, Pages: 144-150, ISSN: 1027-3719
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- Citations: 8
Calderazzo M, Trujillo-Torralbo M, Finney LJ, et al., 2015, Relationship Between Viral Colds And COPD Exacerbations, International Conference of the American-Thoracic-Society (ATS), Publisher: AMER THORACIC SOC, ISSN: 1073-449X
Finney LJ, Toussaint M, Calderazzo M, et al., 2015, Bacterial Load In Stable And Exacerbated COPD, International Conference of the American-Thoracic-Society (ATS), Publisher: AMER THORACIC SOC, ISSN: 1073-449X
Finney L, Berry M, Singanayagam A, et al., 2014, Inhaled corticosteroids and pneumonia in chronic obstructive pulmonary disease, LANCET RESPIRATORY MEDICINE, Vol: 2, Pages: 919-932, ISSN: 2213-2600
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- Citations: 55
Finney LJ, Ritchie A, Pollard E, et al., 2014, Lower airway colonization and inflammatory response in COPD: a focus on Haemophilus influenzae, International Journal of Chronic Obstructive Pulmonary Disease, Vol: 9, Pages: 1119-1132, ISSN: 1176-9106
Bacterial infection of the lower respiratory tract in chronic obstructive pulmonary disease (COPD) patients is common both in stable patients and during acute exacerbations. The most frequent bacteria detected in COPD patients is Haemophilus influenzae, and it appears this organism is uniquely adapted to exploit immune deficiencies associated with COPD and to establish persistent infection in the lower respiratory tract. The presence of bacteria in the lower respiratory tract in stable COPD is termed colonization; however, there is increasing evidence that this is not an innocuous phenomenon but is associated with airway inflammation, increased symptoms, and increased risk for exacerbations. In this review, we discuss host immunity that offers protection against H. influenzae and how disturbance of these mechanisms, combined with pathogen mechanisms of immune evasion, promote persistence of H. influenzae in the lower airways in COPD. In addition, we examine the role of H. influenzae in COPD exacerbations, as well as interactions between H. influenzae and respiratory virus infections, and review the role of treatments and their effect on COPD outcomes. This review focuses predominantly on data derived from human studies but will refer to animal studies where they contribute to understanding the disease in humans.
Gunawardana N, Finney L, Johnston SL, et al., 2014, Experimental rhinovirus infection in COPD: Implications for antiviral therapies, ANTIVIRAL RESEARCH, Vol: 102, Pages: 95-105, ISSN: 0166-3542
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- Citations: 18
Finney LJ, Beasley V, Wan T, et al., 2013, DO SPECIALIST NON-CF BRONCHIECTASIS CLINICS IMPROVE QUALITY OF CARE?, Winter Meeting of the British-Thoracic-Society, Publisher: BMJ PUBLISHING GROUP, Pages: A123-A124, ISSN: 0040-6376
Ross CL, Dimock R, Chotai A, et al., 2013, MANAGEMENT OF PLEURAL EFFUSIONS: ARE HEALTHCARE PROFESSIONALS ADEQUATELY TRAINED?, Winter Meeting of the British-Thoracic-Society, Publisher: BMJ PUBLISHING GROUP, Pages: A107-A107, ISSN: 0040-6376
Craig CEH, Wickremasinghe M, Finney L, et al., 2013, Importance of Onsite Cytopathology at Endobronchial Ultrasound, AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, Vol: 188, Pages: 1164-1164, ISSN: 1073-449X
Finney L, Connell D, O'Donoghue M, et al., 2013, How long do patients with pulmonary tuberculosis remain smear and culture positive?, EUROPEAN RESPIRATORY JOURNAL, Vol: 42, ISSN: 0903-1936
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- Citations: 1
Finney LJ, Feary JR, Leonardi-Bee J, et al., 2013, Chronic obstructive pulmonary disease in sub-Saharan Africa: a systematic review, INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE, Vol: 17, Pages: 583-589, ISSN: 1027-3719
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- Citations: 46
Kwong R, Bradshaw C, Finney L, et al., 2012, DO PATIENTS PROGRESS WHILST UNDERGOING DIAGNOSIS AND STAGING FOR LUNG CANCER: A RETROSPECTIVE AUDIT?, Winter Meeting of the British-Thoracic-Society 2012, Publisher: BMJ PUBLISHING GROUP, Pages: A92-A93, ISSN: 0040-6376
Reid TD, Finney LJ, Hedges AR, 2009, The National Stroke Strategy - is it achievable?, ANNALS OF THE ROYAL COLLEGE OF SURGEONS OF ENGLAND, Vol: 91, Pages: 641-644, ISSN: 0035-8843
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- Citations: 4
Finney L, Solomonidis SE, 2000, To determine hyperelastic soft tissue constants for a finite element model of an amputee's residual limb, XXVth Congress of the Societe-de-Biomecanique and XIth Congress of the Societe-Canadienne-de-Biomecanique, Publisher: SWETS ZEITLINGER PUBLISHERS, Pages: 184-184, ISSN: 1381-3455
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