A postdoctoral Research Associate of the protein crystallisation group in Computational and Systems Medicine.
My initial qualifications are a Master’s degree in Pharmaceutical Chemistry from University of Madras, India. Before moving to England I was in the teaching profession. To seek a career change and move into the field of research, I continued my academic pursuit and completed a honours degree in Biomedical Sciences from University of Greenwich prior to embarking on a PhD programme at Imperial College under Professors Naomi Chayen and John Squire.
Since successful completion of my PhD in 2006, I am working as a Post Doctoral Research Associate with Professor Naomi Chayen in Protein Crystallisation, developing new and improved methods to tackle the bottleneck of protein crystal growth.
Crystallisation and 3-D structure determination of proteins and other biological molecules of medical interest including cancer therapy,diabetes and heart related diseases for the purpose of rational drug design
- Applying phase diagrams to study crystal nucleation and growth
- Design of new, non-standard methodology for production of high-quality crystals for X-ray crystallography
- Design and application of smart and nano materials for crystallization
- Automation and miniaturisation to nano-scale crystallisation in high throughput mode
et al., 2016, Exploring Carbon Nanomaterial Diversity for Nucleation of Protein Crystals, Scientific Reports, Vol:6, ISSN:2045-2322
, et al., 2011, Protein crystallization facilitated by molecularly imprinted polymers, Proceedings of the National Academy of Sciences of the United States of America, Vol:108, ISSN:0027-8424, Pages:11081-11086
, et al., 2009, Attenuated Total Reflection-FT-IR Spectroscopic Imaging of Protein Crystallization, Analytical Chemistry, Vol:81, ISSN:0003-2700, Pages:3769-3775 (Cover)
images displayed at the 'Crystal World' exhibition at the Royal Society. link
Research article featured in Nature Chemistry in News and Views (September 2011)
Scientific imagery displayed at the Crystal World exhibition at the Royal Society (4 July – 5 October 2011).
Image of the day in New Scientist section of Cutting-edge science
Research article evaluated in the top 2% in Faculty of 1000
Co-speaker at Soapbox Science, a public event, at Southbank organised by L'Oreal, the Royal Society and the Zoological Society of London
Outreach events including
Chair: Nucleation Technology Session ICCBM 14, Huntsville Alabama USA
Crystalization of Proteins: Principles and Methods in "Molecules: Nucleation, Aggregation and Crystallization.
Lata Govada (2009) Chapter 7: Ed Sedzik, J. and Riccio P. World Scientific Publishing
Images displayed at the 'Crystal World' exhibition at the Royal Society. link
Active participation in Outreach events including 'Science in the Headlines'
AWARDS and External Positions
President: International Organisation for Biological Crystallisation (IOBCr)
Vice President IOBCr 2016-2018
Council Member IOBCr 2010- 2016
Carl Storm International Diversity Fellowship 2007, Gordon Research Conference.
British Council award to attend STiEX conference 2005, on issues of high technology and scientific development ,Mexico
Prize for best crystallization experimental technique-streak seeding at Recent Advances in Macromolecular Crystallization, France, 2005.
Best speaker at Alternative muscle club, Oxford university 2005
Young Scientist Award at International Conference on the Crystallization of Biological Macromolecules, Beijing 2004
et al., 2022, Graphene-based nucleants for protein crystallization, Advanced Functional Materials, Vol:32, ISSN:1616-301X
et al., 2022, Protein crystals nucleated and grown by means of porous materials display improved X-ray diffraction quality, International Journal of Molecular Sciences, Vol:23, ISSN:1422-0067, Pages:1-13
et al., 2021, X-ray crystallographic studies of RoAb13 bound to PIYDIN, a part of the N-terminal domain of C-C chemokine receptor 5, Iucrj, Vol:8, ISSN:2052-2525, Pages:678-683
Nanev C, Govada L, Chayen N, 2021, Theoretical and experimental investigation on protein crystal nucleation in pores and crevices, Iucrj, Vol:8, ISSN:2052-2525, Pages:270-280
et al., 2021, Analysis of insulin glulisine at the molecular level by X-ray crystallography and biophysical techniques, Scientific Reports, Vol:11, ISSN:2045-2322