Imperial College London

Dr. Lewis Keeble

Faculty of EngineeringDepartment of Electrical and Electronic Engineering

Bid Development Co-ordinator
 
 
 
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Contact

 

l.keeble18

 
 
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Location

 

B422Bessemer BuildingSouth Kensington Campus

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Summary

 

Summary

I joined Imperial in 2018 after being awarded a scholarship with the HiPEDS CDT, under the supervision of Dr. Pantelis Georgiou and Dr. Jesus Rodriguez Manzano at the Centre for Bio-inspired Technology, EEE department. The research that I conducted over the course of my PhD focussed on the fabrication of on-CMOS microelectrode systems to enhance ISFET-based detection of DNA. Primarily, this attempted to use electrokinetic trapping of DNA to boost ISFET signal by localising acid production at the sensing surface. As part of this work I developed novel Monte-Carlo and FEM simulations to model proton diffusion and estimate ISFET signal change depending on DNA positioning. Finally, I used the bond-pads of a commercial CMOS process to create a fully electroplated Ag/AgCl reference electrode on-chip for the first time. Following on from my thesis, my current research interests involve the creation of lab-on-CMOS sample-to-result diagnostic devices utilising electrokinetics for sample preparation.

Before joining Imperial, I received an integrated Masters in Physics (MPhys) at the University of Manchester. My master's project investigated the use of microwave resonators to measure blood glucose levels non-invasively, working as part of the Advanced Technology Group. I was awarded the 2017/18 Platt prize for outstanding experimental work in my master's project.