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@article{Zheng:2023:10.1016/j.lanepe.2023.100635,
author = {Zheng, B and Vivaldi, G and Daines, L and Leavy, OC and Richardson, M and Elneima, O and McAuley, HJC and Shikotra, A and Singapuri, A and Sereno, M and Saunders, RM and Harris, VC and Houchen-Wolloff, L and Greening, NJ and Pfeffer, PE and Hurst, JR and Brown, JS and Shankar-Hari, M and Echevarria, C and De, Soyza A and Harrison, EM and Docherty, AB and Lone, N and Quint, JK and Chalmers, JD and Ho, L-P and Horsley, A and Marks, M and Poinasamy, K and Raman, B and Heaney, LG and Wain, LV and Evans, RA and Brightling, CE and Martineau, A and Sheikh, A and Abel, K and Adamali, H and Adeloye, D and Adeyemi, O and Adrego, R and Aguilar, Jimenez LA and Ahmad, S and Ahmad, Haider N and Ahmed, R and Ahwireng, N and Ainsworth, M and Al-Sheklly, B and Alamoudi, A and Ali, M and Aljaroof, M and All, AM and Allan, L and Allen, RJ and Allerton, L and Allsop, L and Almeida, P and Altmann, D and Alvarez, Corral M and Amoils, S and Anderson, D and Antoniades, C and Arbane, G and Arias, A and Armour,},
doi = {10.1016/j.lanepe.2023.100635},
journal = {The Lancet Regional Health. Europe},
pages = {1--13},
title = {Determinants of recovery from post-COVID-19 dyspnoea: analysis of UK prospective cohorts of hospitalised COVID-19 patients and community-based controls},
url = {http://dx.doi.org/10.1016/j.lanepe.2023.100635},
volume = {29},
year = {2023}
}

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TY  - JOUR
AB  - BackgroundThe risk factors for recovery from COVID-19 dyspnoea are poorly understood. We investigated determinants of recovery from dyspnoea in adults with COVID-19 and compared these to determinants of recovery from non-COVID-19 dyspnoea.MethodsWe used data from two prospective cohort studies: PHOSP-COVID (patients hospitalised between March 2020 and April 2021 with COVID-19) and COVIDENCE UK (community cohort studied over the same time period). PHOSP-COVID data were collected during hospitalisation and at 5-month and 1-year follow-up visits. COVIDENCE UK data were obtained through baseline and monthly online questionnaires. Dyspnoea was measured in both cohorts with the Medical Research Council Dyspnoea Scale. We used multivariable logistic regression to identify determinants associated with a reduction in dyspnoea between 5-month and 1-year follow-up.FindingsWe included 990 PHOSP-COVID and 3309 COVIDENCE UK participants. We observed higher odds of improvement between 5-month and 1-year follow-up among PHOSP-COVID participants who were younger (odds ratio 1.02 per year, 95% CI 1.01–1.03), male (1.54, 1.16–2.04), neither obese nor severely obese (1.82, 1.06–3.13 and 4.19, 2.14–8.19, respectively), had no pre-existing anxiety or depression (1.56, 1.09–2.22) or cardiovascular disease (1.33, 1.00–1.79), and shorter hospital admission (1.01 per day, 1.00–1.02). Similar associations were found in those recovering from non-COVID-19 dyspnoea, excluding age (and length of hospital admission).InterpretationFactors associated with dyspnoea recovery at 1-year post-discharge among patients hospitalised with COVID-19 were similar to those among community controls without COVID-19.FundingPHOSP-COVID is supported by a grant from the MRC-UK Research and Innovation and the Department of Health and Social Care through the National Institute for Health Research (NIHR) rapid response panel to tackle COVID-19. The views expressed in the publica
AU  - Zheng,B
AU  - Vivaldi,G
AU  - Daines,L
AU  - Leavy,OC
AU  - Richardson,M
AU  - Elneima,O
AU  - McAuley,HJC
AU  - Shikotra,A
AU  - Singapuri,A
AU  - Sereno,M
AU  - Saunders,RM
AU  - Harris,VC
AU  - Houchen-Wolloff,L
AU  - Greening,NJ
AU  - Pfeffer,PE
AU  - Hurst,JR
AU  - Brown,JS
AU  - Shankar-Hari,M
AU  - Echevarria,C
AU  - De,Soyza A
AU  - Harrison,EM
AU  - Docherty,AB
AU  - Lone,N
AU  - Quint,JK
AU  - Chalmers,JD
AU  - Ho,L-P
AU  - Horsley,A
AU  - Marks,M
AU  - Poinasamy,K
AU  - Raman,B
AU  - Heaney,LG
AU  - Wain,LV
AU  - Evans,RA
AU  - Brightling,CE
AU  - Martineau,A
AU  - Sheikh,A
AU  - Abel,K
AU  - Adamali,H
AU  - Adeloye,D
AU  - Adeyemi,O
AU  - Adrego,R
AU  - Aguilar,Jimenez LA
AU  - Ahmad,S
AU  - Ahmad,Haider N
AU  - Ahmed,R
AU  - Ahwireng,N
AU  - Ainsworth,M
AU  - Al-Sheklly,B
AU  - Alamoudi,A
AU  - Ali,M
AU  - Aljaroof,M
AU  - All,AM
AU  - Allan,L
AU  - Allen,RJ
AU  - Allerton,L
AU  - Allsop,L
AU  - Almeida,P
AU  - Altmann,D
AU  - Alvarez,Corral M
AU  - Amoils,S
AU  - Anderson,D
AU  - Antoniades,C
AU  - Arbane,G
AU  - Arias,A
AU  - Armour,C
AU  - Armstrong,L
AU  - Armstrong,N
AU  - Arnold,D
AU  - Arnold,H
AU  - Ashish,A
AU  - Ashworth,A
AU  - Ashworth,M
AU  - Aslani,S
AU  - Assefa-Kebede,H
AU  - Atkin,C
AU  - Atkin,P
AU  - Aul,R
AU  - Aung,H
AU  - Austin,L
AU  - Avram,C
AU  - Ayoub,A
AU  - Babores,M
AU  - Baggott,R
AU  - Bagshaw,J
AU  - Baguley,D
AU  - Bailey,L
AU  - Baillie,JK
AU  - Bain,S
AU  - Bakali,M
AU  - Bakau,M
AU  - Baldry,E
AU  - Baldwin,D
AU  - Baldwin,M
AU  - Ballard,C
AU  - Banerjee,A
AU  - Bang,B
AU  - Barker,RE
AU  - Barman,L
AU  - Barratt,S
AU  - Barrett,F
AU  - Basire,D
AU  - Basu,N
AU  - Bates,M
AU  - Bates,A
AU  - Batterham,R
AU  - Baxendale,H
AU  - Bayes,H
AU  - Beadsworth,M
AU  - Beckett,P
AU  - Beggs,M
AU  - Begum,M
AU  - Beirne,P
AU  - Bell,D
AU  - Bell,R
AU  - Bennett,K
AU  - Beranova,E
AU  - Bermperi,A
AU  - Berridge,A
AU  - Berry,C
AU  - Betts,S
AU  - Bevan,E
AU  - Bhui,K
AU  - Bingham,M
AU  - Birchall,K
AU  - Bishop,L
AU  - Bisnauthsing,K
AU  - Blaikely,J
AU  - Bloss,A
AU  - Bolger,A
AU  - Bolton,CE
AU  - Bonnington,J
AU  - Botkai,A
AU  - Bourne,C
AU  - Bourne,M
AU  - Bramham,K
AU  - Brear,L
AU  - Breen,G
AU  - Breeze,J
AU  - Briggs,A
AU  - Bright,E
AU  - Brightling,CE
AU  - Brill,S
AU  - Brindle,K
AU  - Broad,L
AU  - Broadley,A
AU  - Brookes,C
AU  - Broome,M
AU  - Brown,A
AU  - Brown,J
AU  - Brown,JS
AU  - Brown,M
AU  - Brown,V
AU  - Brugha,T
AU  - Brunskill,N
AU  - Buch,M
AU  - Buckley,P
AU  - Bularga,A
AU  - Bullmore,E
AU  - Burden,L
AU  - Burdett,T
AU  - Burn,D
AU  - Burns,G
AU  - Burns,A
AU  - Busby,J
AU  - Butcher,R
AU  - Butt,A
AU  - Byrne,S
AU  - Cairns,P
AU  - Calder,PC
AU  - Calvelo,E
AU  - Carborn,H
AU  - Card,B
AU  - Carr,C
AU  - Carr,L
AU  - Carson,G
AU  - Carter,P
AU  - Casey,A
AU  - Cassar,M
AU  - Cavanagh,J
AU  - Chablani,M
AU  - Chalder,T
AU  - Chalmers,JD
AU  - Chambers,RC
AU  - Chan,F
AU  - Channon,KM
AU  - Chapman,K
DO  - 10.1016/j.lanepe.2023.100635
EP  - 13
PY  - 2023///
SN  - 2666-7762
SP  - 1
TI  - Determinants of recovery from post-COVID-19 dyspnoea: analysis of UK prospective cohorts of hospitalised COVID-19 patients and community-based controls
T2  - The Lancet Regional Health. Europe
UR  - http://dx.doi.org/10.1016/j.lanepe.2023.100635
UR  - https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(23)00054-6/fulltext
UR  - http://hdl.handle.net/10044/1/104228
VL  - 29
ER  -

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