Imperial College London
Alternate

Professor Lefkos Middleton

Faculty of Medicine, School of Public Health

Chair in Clinical Neurology
 
 
 
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Contact

 

+44 (0)20 3311 7290l.middleton CV

 
 
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Assistant

 

Ms Naia Headland-Vanni +44 (0)20 3311 7290

 
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Location

 

Room 10L05 LaboratoryCharing Cross HospitalCharing Cross Campus

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Summary

 

Publications

Publication Type
Year
to

250 results found

Middleton L, Ohno K, Christodoulou K, Brengman J, Milone M, Neocleous V, Serdaroglu P, Deymeer F, Özdemir C, Mubaidin A, Horany K, Al-Shehab A, Mavromatis I, Mylonas I, Tsingis M, Zamba E, Pantzaris M, Kyriallis K, Engel AGet al., 1999, Chromosome 17p-linked myasthenias stem from defects in the acetylcholine receptor ε-subunit gene, NEUROLOGY, Vol: 53, Pages: 1076-1082, ISSN: 0028-3878

Journal article

Christodoulou K, Papadopoulou E, Tsingis M, Engel WK, Askanas V, Middleton LTet al., 1999, Autosomal recessive form of hereditary inclusion body myopathy (AR HIBM): Genetic studies, ISSN: 1128-2460

Conference paper

Pattichis CS, Schofield I, Merletti R, Parker PA, Middleton LTet al., 1999, Introduction to this Special Issue - Intelligent data analysis in electromyography and electroneurography, MEDICAL ENGINEERING & PHYSICS, Vol: 21, Pages: 379-388, ISSN: 1350-4533

Journal article

Georgiou DM, Christodoulou K, Zamba E, Deymeer F, Serdaroglu P, Parman Y, Ozdemir C, Horany H, Khalifa A, Jedrzejowska H, Hausmanova-Petrusewicz I, Mubaidin A, Horani K, Politano L, Middleton LTet al., 1999, Molecular genetic studies in autosomal recessive CMT, ISSN: 1128-2460

Conference paper

Kyriakides T, Kassianides B, Papadopoulou E, Kyriacou K, Drousiotou A, Christodoulou K, Middleton LTet al., 1999, A Cypriot family with a novel γ-sarcoglycan mutation presenting clinically and immunocytochemically as Becker muscular dystrophy (BMD), ISSN: 1128-2460

Conference paper

Middleton LT, Christodoulou K, Mubaidin A, Zamba E, Tsingis M, Kyriacou K, Abu-Sheikh S, Kyriakides T, Neocleous V, Georgiou DM, El-Khateeb M, Al-Qudah A, Horany Ket al., 1999, Distal hereditary motor neuronopathy of the Jerash type, CHARCOT-MARIE-TOOTH DISORDERS, Vol: 883, Pages: 439-442, ISSN: 0077-8923

Journal article

Middleton LT, Christodoulou K, Mubaidin A, Zamba E, Tsingis M, Kyriacou K, Abu-Sheikh S, Kyriakides T, Neocleous V, Georgiou DM, El-Khateeb M, Al-Qudah A, Horany Ket al., 1999, Distal hereditary motor neuronopathy of the Jerash type, CHARCOT-MARIE-TOOTH DISORDERS, Vol: 883, Pages: 65-68, ISSN: 0077-8923

Journal article

Middleton LT, Pantzaris M, Zamba E, Kyriallis K, Christodoulou Ket al., 1998, Inherited myasthenic syndromes, Pages: 47-53, ISSN: 1128-2460

Conference paper

Kyriakides T, Christodoulou K, Zamba E, Middleton Let al., 1998, Hereditary motor neuronopathies, clinical, neurophysiological and genetic aspects, Pages: 55-58, ISSN: 1128-2460

Conference paper

Christodoulou K, Papadopoulou E, Tsingis M, Askanas V, King Engel W, Ferrin J, Dalakas M, Rowland LP, Mirabella M, Middleton LTet al., 1998, Narrowing of the gene locus for autosomal-recessive quadriceps sparing inclusion-body myopathy (ARQS-IBM) to chromosome 9p1, Acta Myologica, Vol: 2, Pages: 7-9, ISSN: 1128-2460

Journal article

Kalaydjieva L, Nikolova A, Turnev I, Petrova J, Hristova A, Ishpekova B, Petkova I, Shmarov A, Stancheva S, Middleton L, Merlini L, Trogu A, Muddle JR, King RHM, Thomas PKet al., 1998, Hereditary motor and sensory neuropathy - Lom, a novel demyelinating neuropathy associated with deafness in gypsies - Clinical, electrophysiological and nerve biopsy findings, BRAIN, Vol: 121, Pages: 399-408, ISSN: 0006-8950

Journal article

Drousiotou A, Ioannou P, Georgiou T, Mavrikiou E, Christopoulos G, Kyriakides T, Voyasianos M, Argyriou A, Middleton Let al., 1998, Neonatal screening for Duchenne muscular dystrophy: A novel semiquantitative application of the bioluminescence test for creatine kinase in a pilot national program in cyprus, GENETIC TESTING, Vol: 2, Pages: 55-60, ISSN: 1090-6576

Journal article

Middleton LT, Christodoulou K, Deymeer F, Serdaroglu P, Ozdemir C, Al-Qudah AK, Al-Shehab A, Mavromatis I, Mylonas I, Evoli A, Tsingis M, Zamba E, Kyriallis Ket al., 1998, Congenital myasthenic syndrome (CMS) Type Ia - Clinical and genetic diversity, MYASTHENIA GRAVIS AND RELATED DISEASES, Vol: 841, Pages: 157-166, ISSN: 0077-8923

Journal article

Christodoulou K, Deymeer F, Serdaroglu P, Ozdemir C, Georgiou DM, Papadopoulou E, Zamba E, Middleton LTet al., 1997, Genetic heterogeneity in Friedreich's ataxia: indication for a second locus on chromosome 9., AMERICAN JOURNAL OF HUMAN GENETICS, Vol: 61, Pages: A271-A271, ISSN: 0002-9297

Journal article

Lennon F, Pericak-Vance MA, Speer MC, West SG, Menold MM, Stajich JM, Wolpert CM, Slotterbeck BD, Saito M, Tim RW, Rozear MP, Middleton LT, Tsuji S, Vance JMet al., 1997, CMT2 mapping progress: Confirmation of a second locus and evidence for additional genetic heterogeneity., AMERICAN JOURNAL OF HUMAN GENETICS, Vol: 61, Pages: A282-A282, ISSN: 0002-9297

Journal article

Tao YY, Blomeier H, Richards C, Stajich JM, Gaskell P, Slotterbeck B, Tsuji S, Middleton L, Pericak-Vance MA, Ben-Othmane K, Vance JMet al., 1997, Refinement of the Charcot-Marie-Tooth type 2 (CMT2A) region on chromosome 1p36.2 and formation of a YAC/PAC contig., AMERICAN JOURNAL OF HUMAN GENETICS, Vol: 61, Pages: A245-A245, ISSN: 0002-9297

Journal article

Neocleous V, Middleton LT, Christodoulou K, 1997, Mutation screening in the synaptobrevin-2 gene in patients with familial infantile myasthenia., AMERICAN JOURNAL OF HUMAN GENETICS, Vol: 61, Pages: A341-A341, ISSN: 0002-9297

Journal article

Pericak-Vance MA, Speer MC, Lennon F, West SG, Menold MM, Stajich JM, Wolpert CM, Slotterbeck BD, Saito M, Tim RW, Rozear MP, Middleton LT, Tsuji S, Vance JMet al., 1997, Confirmation of a second locus for CMT2 and evidence for additional genetic heterogeneity, NEUROGENETICS, Vol: 1, Pages: 89-93, ISSN: 1364-6745

Journal article

Christodoulou K, Tsingis M, Deymeer F, Serdaroglu P, Ozdemir C, AlShehab A, Bairactaris C, Mavromatis I, Mylonas I, Evoli A, Kyriallis K, Middleton LTet al., 1997, Mapping of the familial infantile myasthenia (congenital myasthenic syndrome type Ia) gene to chromosome 17p with evidence of genetic homogeneity, HUMAN MOLECULAR GENETICS, Vol: 6, Pages: 635-640, ISSN: 0964-6906

Journal article

Dean G, Aksoy H, Akalin T, Middleton L, Kyriallis Ket al., 1997, Multiple sclerosis in the Turkish- and Greek-speaking communities of Cyprus - A United Nations (UNHCR) Bicommunal Project, JOURNAL OF THE NEUROLOGICAL SCIENCES, Vol: 145, Pages: 163-168, ISSN: 0022-510X

Journal article

Patsalis PC, Sismani C, Hadjimarcou MI, Rose N, Stylianidou G, Koukoulli R, Anastasiadou V, Deltas CC, Middleton Let al., 1997, Cytogenetic and fragile X molecular testing of individuals with mental retardation of unknown etiology, GENETIC COUNSELING, Vol: 8, Pages: 1-6, ISSN: 1015-8146

Journal article

Angastiniotis M, Middleton L, 1997, Genetic services in cyprus, EUROPEAN JOURNAL OF HUMAN GENETICS, Vol: 5, Pages: 51-57, ISSN: 1018-4813

Journal article

Kyriakides T, Christodoulou K, Socdiono O, Kyriakou K, Shehab AA, Dasouki M, Khouri M, Al-Din AN, Vance J, Ozawa E, Middleton Let al., 1996, Severe childhood autosomal recessive muscular dystrophy (SCARMD) in jordan exhibits heterogeneity at protein and DNA level, ISSN: 1124-8874

Conference paper

Kalaydjieva L, Hallmayer J, Chandler D, Savov A, Nikolova A, Angelicheva D, King RHH, Ishpekova B, Honeyman K, Calafell F, Shmarov A, Petrova J, Turnev I, Hristova A, Moskov M, Stancheva S, Petkova I, Bittles AH, Georgieva V, Middleton L, Thomas PKet al., 1996, Gene mapping in Gypsies identifies a novel demyelinating neuropathy on chromosome 8q24, NATURE GENETICS, Vol: 14, Pages: 214-217, ISSN: 1061-4036

Journal article

Middleton LT, 1996, Congenital myasthenic syndromes - 34th ENMC international workshop, 10-11 June 1995, NEUROMUSCULAR DISORDERS, Vol: 6, Pages: 133-136, ISSN: 0960-8966

Journal article

NOGUCHI S, MCNALLY EM, BENOTHMANE K, HAGIWARA Y, MIZUNO Y, YOSHIDA M, YAMAMOTO H, BONNEMANN CG, GUSSONI E, DENTON PH, KYRIAKIDES T, MIDDLETON L, HENTATI F, BENHAMIDA M, NONAKA I, VANCE JM, KUNKEL LM, OZAWA Eet al., 1995, MUTATIONS IN THE DYSTROPHIN-ASSOCIATED PROTEIN GAMMA-SARCOGLYCAN IN CHROMOSOME-13 MUSCULAR-DYSTROPHY, SCIENCE, Vol: 270, Pages: 819-822, ISSN: 0036-8075

Journal article

CHRISTODOULOU K, KYRIAKIDES T, HRISTOVA AH, GEORGIOU DM, KALAJDJIEVA L, YSHPEKOVA B, IVANOVA T, WEBER JL, MIDDLETON LTet al., 1995, MAPPING OF AN AUTOSOMAL-DOMINANT DISTAL FORM OF SPINAL MUSCULAR-ATROPHY TO CHROMOSOME 7P, AMERICAN JOURNAL OF HUMAN GENETICS, Vol: 57, Pages: 1082-1082, ISSN: 0002-9297

Journal article

BENOTHMANE K, SPEER MC, STAUFFER J, BLEL S, MIDDLETON L, BENHAMIDA C, ETRIBI A, LOEB D, HENTATI F, ROSES AD, BENHAMIDA M, PERICAKVANCE MA, VANCE JMet al., 1995, EVIDENCE FOR LINKAGE DISEQUILIBRIUM IN CHROMOSOME 13-LINKED DUCHENNE-LIKE MUSCULAR-DYSTROPHY (LGMD2C), AMERICAN JOURNAL OF HUMAN GENETICS, Vol: 57, Pages: 732-734, ISSN: 0002-9297

Journal article

CHRISTODOULOU K, KYRIAKIDES T, HRISTOVA AH, GEORGIOU DM, KALAYDJIEVA L, YSHPEKOVA B, IVANOVA T, WEBER JL, MIDDLETON LTet al., 1995, MAPPING OF A DISTAL FORM OF SPINAL MUSCULAR-ATROPHY WITH UPPER-LIMB PREDOMINANCE TO CHROMOSOME 7P, HUMAN MOLECULAR GENETICS, Vol: 4, Pages: 1629-1632, ISSN: 0964-6906

Journal article

PATTICHIS CS, CHARALAMBOUS C, MIDDLETON LT, 1995, EFFICIENT TRAINING OF NEURAL-NETWORK MODELS IN CLASSIFICATION OF ELECTROMYOGRAPHIC DATA, MEDICAL & BIOLOGICAL ENGINEERING & COMPUTING, Vol: 33, Pages: 499-503, ISSN: 0140-0118

Journal article

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