Imperial College London

ProfessorLesleyRegan

Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Clinical Professor
 
 
 
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Contact

 

+44 (0)20 3312 1798l.regan

 
 
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Assistant

 

Ms Hazel Blackman +44 (0)20 7594 2104

 
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Location

 

MWG022Mint WingSt Mary's Campus

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Summary

 

Publications

Publication Type
Year
to

355 results found

Stewart EA, Rabinovici J, Tempany CMC, Inbar Y, Hindley J, Regan L, Gastout B, Hesley G, Kim HS, Hengst S, Gedroye WMet al., 2006, Clinical outcomes of focused ultrasound surgery for the treatment of uterine fibroids, FERTILITY AND STERILITY, Vol: 85, Pages: 22-29, ISSN: 0015-0282

Journal article

Backos M, Regan L, 2006, Recurrent miscarriage, High Risk Pregnancy: Management Options, Editors: James, Steer, Weiner, Gonik, Philadelphia, Pennsylvania, Publisher: Elsevier Saunders, Pages: 105-124

Book chapter

Malik MK, Regan L, Robinson-Bostom L, Pan TD, McDonald CJet al., 2005, Proliferating multicentric reticulohistiocytosis associated with papillary serous carcinoma of the endometrium, JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, Vol: 53, Pages: 1075-1079, ISSN: 0190-9622

Journal article

Carrington B, Sacks G, Regan L, 2005, Recurrent miscarriage: pathophysiology and outcome, CURRENT OPINION IN OBSTETRICS & GYNECOLOGY, Vol: 17, Pages: 591-597, ISSN: 1040-872X

Journal article

Wu O, Robertson L, Twaddle S, Lowe G, Clark P, Walker I, Brenkel I, Greaves M, Langhorne P, Regan L, Greer Iet al., 2005, Screening for thrombophilia in high-risk situations: a meta-analysis and cost-effectiveness analysis, BRITISH JOURNAL OF HAEMATOLOGY, Vol: 131, Pages: 80-90, ISSN: 0007-1048

Journal article

Wu O, Robertson L, Langhorne P, Twaddle S, Lowe GDO, Clark P, Greaves M, Walker ID, Brenkel I, Regan L, Greer IAet al., 2005, Oral contraceptives, hormone replacement therapy, thrombophilias and risk of venous thromboembolism: a systematic review, THROMBOSIS AND HAEMOSTASIS, Vol: 94, Pages: 17-25, ISSN: 0340-6245

Journal article

Wimalasundera RC, Thom SAM, Regan L, Hughes ADet al., 2005, Effects of vasoactive agents on intracellular calcium and force in myometrial and subcutaneous resistance arteries isolated from preeclamptic, pregnant, and nonpregnant woman, AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, Vol: 192, Pages: 625-632, ISSN: 0002-9378

Journal article

Regan L, Carrington B, Rasul S, Lawn A, Rai Ret al., 2005, Polycystic ovaries, insulin resistance, hypofibrinolysis and recurrent miscarriage., 52nd Annual Meeting of the Society-for-Gynecologic-Investigation, Publisher: ELSEVIER SCIENCE INC, Pages: 91A-92A, ISSN: 1071-5576

Conference paper

Sebire NJ, Goldin RD, Regan L, 2005, Term preeclampsia is associated with minimal histopathological placental features regardless of clinical severity., J Obstet Gynaecol, Vol: 25, Pages: 117-118, ISSN: 0144-3615

Preeclampsia (PET) is a serious complication of pregnancy, which is associated with uteroplacental disease and reduced uteroplacental perfusion. One of the histological features in placentas from pregnancies complicated by PET is infarction, representing focal severe uteroplacental ischaemia. This study examines the relationship between gestation at induced delivery and the prevalence of placental infarction using a placental pathology database to identify induced or operative deliveries on the basis of severe PET. The clinical and pathological findings were reviewed. Thirty-seven cases were identified, (4.9% of all placentas submitted). In 16 (43%), non-peripheral significant infarcts were identified histologically, including 13/20 (65%) requiring delivery before 34 weeks' compared to 3/17 (17%) requiring delivery > or = 34 weeks (z=2.9, P<0.01). Histological infarction is common in placentas from pregnancies complicated by severe PET but the prevalence is significantly greater in cases requiring delivery at earlier gestations, even when similar clinical indications for delivery are applied.

Journal article

Bose P, Black S, Kadyrov M, Weissenborn U, Neuten J, Regan L, Huppertz Bet al., 2005, Heparin and aspirin attenuate placental apoptosis in vitro: Implications for early pregnancy failure, AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, Vol: 192, Pages: 23-30, ISSN: 0002-9378

Journal article

Vashisht A, Regan L, 2005, Antiphospholipid syndrome in pregnancy - an update, Publication following RCP Edinburgh's Maternal Medicine Conference May 2005, Publisher: Available on RCPE website www.rcpe.ac.uk/fellows/CME/index.html

Book chapter

Smart O, Hindley J, Regan L, Gedroyc Wet al., 2005, Magnetic resonance guided focused ultrasound of uterine fibroids, 19th Asian and Oceanic Congress of Obstetrics and Gynecology, Publisher: MEDIMOND S R L, Pages: 331-335

Conference paper

Vashisht A, Regan L, 2005, Recurrent early pregnancy loss: the role of haemostatic disorders, Proceedings of the 48th RCOG study group on Implantation and Early Development, Editors: Critchley, Cameron, Smith, Pages: 229-239

Book chapter

REGAN L, 2005, SUA GRAVIDEZ SEMANA A SEMANA, A, Publisher: Dorling Kindersley, ISBN: 9789895502943

Book

Bose P, Black S, Kadyrov M, Bartz C, Shlebak A, Regan L, Huppertz Bet al., 2004, Adverse effects of lupus anticoagulant positive blood sera on placental viability can be prevented by heparin in vitro, AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, Vol: 191, Pages: 2125-2131, ISSN: 0002-9378

Journal article

Hindley J, Gedroyc WM, Regan L, Stewart E, Tempany C, Hynnen K, Macdanold N, Inbar Y, Itzchak Y, Rabinovici J, Kim K, Geschwind JF, Hesley G, Gostout B, Ehrenstein T, Hengst S, Sklair-Levy M, Shushan A, Jolesz Fet al., 2004, MRI guidance of focused ultrasound therapy of uterine fibroids: Early results, AMERICAN JOURNAL OF ROENTGENOLOGY, Vol: 183, Pages: 1713-1719, ISSN: 0361-803X

Journal article

Moffett A, Regan L, Braude P, 2004, Natural killer cells, miscarriage, and infertility, BMJ-BRITISH MEDICAL JOURNAL, Vol: 329, Pages: 1283-1285, ISSN: 1756-1833

Journal article

Leonce J, Robinson S, Johnston D, Venkatasen S, Bannister P, Raman V, Steer P, Murphy K, Daniels K, Parker K, Pavitt D, Teoh TG, Regan Let al., 2004, Placental glucose metabolism in normal pregnancy and intrauterine growth restriction, Conference of the Placenta-Association-of-the-Americas/10th Meeting of the International-Federation-of-Placenta, Publisher: W B SAUNDERS CO LTD, Pages: A49-A49, ISSN: 0143-4004

Conference paper

Sebire NJ, Goldin RD, Regan L, 2004, The association between early gestational age and placental infarction in pregnancies complicated by severe pre-eclampsia, 186th Meeting of the Pathological-Society-of-Great-Britain-and-Ireland/Dutch-Pathological-Society, Publisher: WILEY-BLACKWELL, Pages: 40A-40A, ISSN: 0022-3417

Conference paper

Robertson L, Wu O, Langhorne P, Twaddle S, Clark P, Lowe GD, Walker I, Brenkel I, Greaves M, Regan L, Greer IAet al., 2004, Thrombophilia in pregnancy: a systematic review, Annual Scientific Meeting of the British-Society-for-Haematology, Publisher: BLACKWELL PUBLISHING LTD, Pages: 35-36, ISSN: 0007-1048

Conference paper

Francis J, El-Gaddal S, Regan L, Raj R, Brosens Jet al., 2004, Unexplained recurrent miscarriages are associated with altered endometrial STAT1/STAT5 expression., 51st Annual Meeting of the Society-for-Gynecologic-Investigation, Publisher: ELSEVIER SCIENCE INC, Pages: 291A-291A, ISSN: 1071-5576

Conference paper

Backos M, Rai R, Rushworth F, Regan Let al., 2004, The clinical course of antiphospholipid antibodies in women with a history of recurrent miscarriage: A prospective longitudinal study., 51st Annual Meeting of the Society-for-Gynecologic-Investigation, Publisher: ELSEVIER SCIENCE INC, Pages: 377A-377A, ISSN: 1071-5576

Conference paper

Backos M, Rai R, El-Gaddal S, Regan Let al., 2004, Effect of the duration of aspirin plus heparin treatment on the rate of preterm birth in women with antiphospholipid syndrome: A randomised controlled trial., 51st Annual Meeting of the Society-for-Gynecologic-Investigation, Publisher: ELSEVIER SCIENCE INC, Pages: 201A-201A, ISSN: 1071-5576

Conference paper

Bagratee JS, Khullar V, Regan L, Moodley J, Kagoro Het al., 2004, A randomized controlled trial comparing medical and expectant management of first trimester miscarriage, HUMAN REPRODUCTION, Vol: 19, Pages: 266-271, ISSN: 0268-1161

Journal article

Rai R, Backos M, El'Gaddal S, Regan Let al., 2004, Recurrent miscarriage and parental karyotype abnormalities - Prospcetive pregnancy outcome of spontaneously conceived pregnancies., 51st Annual Meeting of the Society-for-Gynecologic-Investigation, Publisher: ELSEVIER SCIENCE INC, Pages: 376A-376A, ISSN: 1071-5576

Conference paper

Boffa MC, Lachassinne E, Aurousseau MH, Uzan M, Fain O, Rai R, Sangle S, Avcin T, Farge D, Douart P, Piette JC, Regan L, Hughes GRVet al., 2004, Thrombotic and vascular events in babies born to mothers with APS or APLA, 11th International Congress on Antiphospholipid Antibodies, Publisher: PERGAMON-ELSEVIER SCIENCE LTD, Pages: 622-623, ISSN: 0049-3848

Conference paper

Backos M, Regan L, 2004, Antiphospholipid syndrome and preterm birth, Proceedings of the 46th RCOG study group on Preterm Birth, Editors: Critchley, Thornton, Publisher: RCOG Press, Pages: 239-243

Book chapter

Jolly MC, Sebire NJ, Harris JP, Regan L, Robinson Set al., 2003, Risk factors for macrosomia and its clinical consequences: a study of 350,311 pregnancies, EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, Vol: 111, Pages: 9-14, ISSN: 0301-2115

Journal article

Salim R, Woelfer B, Backos M, Regan L, Jurkovic Det al., 2003, Reproducibility of three-dimensional ultrasound diagnosis of congenital uterine anomalies, ULTRASOUND IN OBSTETRICS & GYNECOLOGY, Vol: 21, Pages: 578-582, ISSN: 0960-7692

Journal article

Wimalasundera R, Fexby S, Regan L, Hughes ADet al., 2003, Effect of tumour necrosis factor-α and interleukin 1β on endothelium-dependent relaxation in rat mesenteric resistance arteries <i>in vitro</i>, BRITISH JOURNAL OF PHARMACOLOGY, Vol: 138, Pages: 1285-1294, ISSN: 0007-1188

Journal article

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