Imperial College London

Dr Lynne Sykes

Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Clinical Senior Lecturer
 
 
 
//

Contact

 

+44 (0)20 7594 2186l.sykes Website

 
 
//

Location

 

3007Institute of Reproductive and Developmental BiologyHammersmith Campus

//

Summary

 

Student supervision:

BSc

2015 Boyce,E. The effects of therapeutic concentrations of Sulfasalazine in amniocytes and Proinflammatory Genes in Human Amnion Epithelial Cells

2017 Anucha,E. The potential role of viral priming in the placenta in bacterial induced preterm labour

2018 Thurairajah, S. Peripheral blood neutrophil function in women at high risk of preterm labour (BSc in Immunology)

2019 Budwig, L. Leukocytes as predictive markers of histological chorioamnionitis in women with preterm prelabour rupture of fetal membranes

2020 Hyde, A. Maternal ABO phenotype and the risk of preterm birth

2022 Pasint-Magyar, J. Maternal ABO phenotype and the risk of preterm birth in a large population study

2022 Green, A. Maternal ABO phenotype and the risk of PPROM in a large population study

 

MSc

2010 Hunte,E. The role of CRTH2 in murine myometrial contractility

2011 Yap,XJ. Chemoattractant Receptor Homologous to the T helper 2 cell (CRTH2) expression and function in T helper cells in pregnancy

2013 Thomson,K. Investigation of Sulfasalazine Treatment in the Prevention of Preterm Labour – Effect on NF-κB Activity

2014 Begum,Z. The anti-inflammatory effects of 15dPGJ2 in human cultured amniocytes

2017 Rai, R. The role of TLR3 in viral priming of myocytes

2017 Bura, S. Recognition of the vaginal microbiome by the maternal immune response in pregnancy.

2018 Ahmed, S. The vaginal microbiota and the local and systemic immune response in term and preterm deliveries

2018 San Martin, C.  The role of TLR3 in viral priming of PBMCs

2018 Alqurashi, M. Normal and low density granulocytes in pregnancy, Labour and women at high risk of preterm labour (MSc in Immunology)

 

 

PhD

2019 Begam,Z, The role of viral priming in bacterial induced preterm labour

2020 Chan,D, Microbial – Maternal Host Immune Interactions in Pregnancy Preterm labour

Current: Gimeno-Molina,B, The role of neutrophils in microbial driven preterm birth

Current: Mountain, K. Patient stratification and prediction of preterm labour in women with prior cervical treatment and women with a history of PTB

Current: Preda, V. Preterm birth, HIV and the immune response.

 

Collaborators

Dr Maria Carmen Collado, The Institute of Agrochemistry and Food Technology (IATA), Maternal and infant gut microbiome, 2016

Marcelo Napimoga, Centro de Pesquisas em Odontologia Sao Leopoldo Mandic, Sao Paulo, Brazil, Nanoparticle technology for the delivery of prostaglandins, 2016

Research Student Supervision

Ahmed,S, The vaginal microbiota and the local and systemic immune response in term and preterm deliveries (MSc)

Alqurashi,M, Normal and low density granulocytes in pregnancy, Labour and women at high risk of preterm labour (MSc in Immunology)

Anucha,E, The potential role of viral priming in the placenta in bacterial induced preterm labour (BSc)

Begam,Z, The role of viral priming in bacterial induced preterm labour (PhD)

Begam,Z, The anti-inflammatory effects of 15dPGJ2 in human cultured amniocytes (MSc)

Boyce,E, The effects of therapeutic concentrations of Sulfasalazine in amniocytes and Proinflammatory Genes in Human Amnion Epithelial Cells (BSc)

Budwig,L, Leukocytes as predictive markers of histological chorioamnionitis in women with preterm prelabour rupture of fetal membranes (BSc)

Bura,S, Recognition of the vaginal microbiome by the maternal immune response in pregnancy (MSc)

Chan,D, Microbial – Maternal Host Immune Interactions in Pregnancy Preterm labour (PhD)

Hunte,E, The role of CRTH2 in murine myometrial contractility (MSc)

Hyde,A, Maternal ABO phenotype and the risk of preterm birth (BSc)

Rai,R, The role of TLR3 in viral priming of myocytes (MSc)

San Martin,C, The role of TLR3 in viral priming of PBMCs (MSc)

Thomson,K, Investigation of Sulfasalazine Treatment in the Prevention of Preterm Labour – Effect on NF-κB Activity (MSc)

Thurairajah,S, Peripheral blood neutrophil function in women at high risk of preterm labour (BSc in Immunology)

Yap,XJ, Chemoattractant Receptor Homologous to the T helper 2 cell (CRTH2) expression and function in T helper cells in pregnancy (MSc)