Imperial College London

DrLukeTyson

Faculty of MedicineDepartment of Metabolism, Digestion and Reproduction

Honorary Clinical Research Fellow
 
 
 
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Contact

 

l.tyson CV

 
 
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Location

 

Queen Elizabeth the Queen Mother Wing (QEQM)St Mary's Campus

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Summary

 

Publications

Publication Type
Year
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26 results found

Tyson LD, Atkinson S, Hunter RW, Thursz M, Vergis Net al., 2024, Editorial: Unmasking the silent threat-acute kidney injury in alcohol-associated hepatitis. Authors' reply., Aliment Pharmacol Ther, Vol: 59, Pages: 124-125

Journal article

Smith PJ, 2023, GI highlights from the literature, Gut, ISSN: 0017-5749

Journal article

Tyson LD, Atkinson S, Hunter RW, Allison M, Austin A, Dear JW, Forrest E, Liu T, Lord E, Masson S, Nunes J, Richardson P, Ryder SD, Wright M, Thursz M, Vergis Net al., 2023, In severe alcohol-related hepatitis, acute kidney injury is prevalent, associated with mortality independent of liver disease severity, and can be predicted using IL-8 and micro-RNAs, ALIMENTARY PHARMACOLOGY & THERAPEUTICS, ISSN: 0269-2813

Journal article

Smith PJ, 2023, GI highlights from the literature, Gut, ISSN: 0017-5749

Journal article

Smith PJ, 2023, GI highlights from the literature, Gut, ISSN: 0017-5749

Journal article

Tyson LD, Lewis H, 2022, Response to 'acamprosate better than baclofen for alcohol use disorder in cirrhosis: fact or myth?', EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, Vol: 34, Pages: 976-976, ISSN: 0954-691X

Journal article

Ryan JM, Adams H, Tsou HL, Devshi D, Harris N, Sieh YX, Hadzhiolova T, Pavlova S, Fairclough S, Atkinson S, Tyson L, Wright G, Patel V, Evans A, Simonova M, Katzarov K, Shawcross DL, Bajaj J, Fagan A, McQuillin A, Thursz M, Morgan MY, Riva A, Chokshi Set al., 2022, Interferon lambda 4 genetic variants are associated with bacterial infection during alcohol-related liver disease, Publisher: WILEY, Pages: 85-85, ISSN: 0145-6008

Conference paper

Smith PJ, 2022, GI highlights from the literature, Gut

Journal article

Vergis N, Hall I, Arthurs C, Kudo H, Atkinson S, Shapiro D, Lutz M, Jung B, Weissbach M, Albrecht W, Tyson LD, Liu T, Lord E, Zender L, Thursz M, Goldin RDet al., 2022, In severe alcohol-related hepatitis, hepatocyte ballooning correlates with expression of p16 and components of a secretory phenotype that has been associated with cellular senescence, International Liver Congress, Publisher: ELSEVIER, Pages: S132-S132, ISSN: 0168-8278

Conference paper

Tebeka NN, Atkinson S, Tyson LD, Argemi J, Syanda A, Bataller R, Rashid T, Thursz Met al., 2022, Loss of solute carrier family 38 member 4 (SLC38A4) as a driver for the pathogenesis of severe alcoholic hepatitis, Publisher: ELSEVIER, Pages: S140-S141, ISSN: 0168-8278

Conference paper

Vutipongsatorn K, Nagy E, Jethwa A, Sharif A, Tyson Let al., 2022, An evaluation of paired feedback from a year-long junior doctor-led teaching programme., Future Healthc J, Vol: 9, Pages: 47-48, ISSN: 2514-6645

Journal article

Tyson LD, Atkinson S, Allison M, Austin A, Cross L, Dear J, Forrest E, Liu T, Lord E, Masson S, Nunes J, Richardson P, Ryder S, Wright M, Thursz M, Vergis Net al., 2022, Incident acute kidney injury in severe alcohol-related hepatitis is strongly associated with mortality and can be predicted using micro-RNAs and markers of systemic inflammation, Publisher: ELSEVIER, Pages: S122-S122, ISSN: 0168-8278

Conference paper

Smith PJ, 2022, GI highlights from the literature, Gut, ISSN: 0017-5749

Journal article

Tyson LD, Cheng A, Kelleher C, Strathie K, Lovendoski J, Habtemariam Z, Lewis Het al., 2022, Acamprosate may be safer than baclofen for the treatment of alcohol use disorder in patients with cirrhosis: a first description of use in real-world clinical practice, EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY, Vol: 34, Pages: 567-575, ISSN: 0954-691X

Journal article

Atkinson SR, Aly M, Remih K, Tyson LD, Guldiken N, Goldin R, Quaglia A, Thursz M, Strnad Pet al., 2022, Serum keratin 19 (CYFRA21-1) is a prognostic biomarker in severe alcoholic hepatitis, LIVER INTERNATIONAL, Vol: 42, Pages: 1049-1057, ISSN: 1478-3223

Journal article

Tyson L, Thursz PM, Forrest E, Allison M, Vergis N, Atkinson Set al., 2021, INCIDENT ACUTE KIDNEY INJURY HAS A WORSE PROGNOSIS THAN BASELINE IN SEVERE ALCOHOLIC HEPATITIS, Publisher: BMJ PUBLISHING GROUP, Pages: A25-A26, ISSN: 0017-5749

Conference paper

Tyson LD, Cheng A, Kelleher C, Strathie K, Lovendoski J, Habtemariam Z, Lewis Het al., 2021, Acamprosate for the treatment of alcohol use disorder may be safer than baclofen in patients with cirrhosis, International Liver Congress, Publisher: ELSEVIER, Pages: S314-S314, ISSN: 0168-8278

Conference paper

Ryan JM, Adams HL, Devshi D, Atkinson S, Tyson L, Shawcross DL, Wright G, Fairclough S, Evans A, Simonova M, Katzarov K, Hadzhiolova T, Pavlova S, Bajaj J, Fagan A, Thursz M, Williams R, McQuillin A, Morgan MY, Riva A, Chokshi Set al., 2021, Interferon lambda 4 is associated with dysfunctional antibacterial immunity during alcohol-related liver disease, Publisher: ELSEVIER, Pages: S207-S208, ISSN: 0168-8278

Conference paper

Tyson L, Forlano R, Ulucay E, Vergis N, Giannakeas N, Tzallas A, Thursz M, Goldin R, Atkinson S, Manousou Pet al., 2021, Automated quantitation of histological features could predictmortality in patients with severe alcoholic hepatitis, ILC 2021, Publisher: Elsevier, ISSN: 0168-8278

Conference paper

Woodfield G, Tyson LD, Orhan O, Szram Jet al., 2021, Development of a north-west London paracentesis simulation course for core medical trainees., Future Healthc J, Vol: 8, Pages: e131-e136, ISSN: 2514-6645

We designed, implemented and evaluated a near-peer simulation training programme teaching diagnostic and therapeutic abdominal paracentesis to core medical trainees (CMTs). We taught diagnostic and therapeutic abdominal paracentesis to 77 north-west London CMTs over 8 training days over 4 years, 2015 to 2019. The programme was optimised by use of plan, do, study, act (PDSA) cycles and the content was evaluated by anonymous pre- and post-course questionnaires. There was a need for this training; 89% of participants reported inadequate training opportunities pre-course and only 28% felt 'confident' or 'very confident' to insert an ascitic drain. Simulation training appears effective when teaching these skills. Having been low in confidence before the course, all participants reported increased confidence after completing the course. Simulation training has been highlighted as a key aspect of the new internal medicine training programme, which replaces CMT. We would recommend using PDSA cycles to implement effective simulation programmes.

Journal article

Cemente A, Atkinson S, Tyson LD, Ventura Cots M, Argemi J, Vergis N, Manimaran S, Morgan MY, McQuillin A, Arraez DM, Alvarado-Tapias E, Fernandez-Carrillo C, Olivera-Mello A, Abraldes JG, Bosques FJ, Brown RS, Caballeria J, Garcia-Tsao G, Genesca J, Lucey MR, Louvet A, Mathurin P, Schnabl B, Shawcross DL, Vargas V, Verna EC, Thursz MR, Bataller Ret al., 2020, EARLY ALCOHOL RELAPSE AFTER AN EPISODE OF ALCOHOL-INDUCED HEPATITIS (AH): PREVALENCE, IMPACT ON LIVER FUNCTION, GENETIC AND NON -GENETIC FACTORS AND IDENTIFICATION OF DISTINCT RISK PROFILES., Liver Meeting of the American-Association-for-the-Study-of-Liver-Diseases (AASLD), Publisher: WILEY, Pages: 158A-159A, ISSN: 0270-9139

Conference paper

Ryan J, Adams H, Atkinson S, Tyson L, Fairclough S, Wright G, Evans A, Bajaj J, Fagan A, Shawcross D, Thursz M, McQuillan A, Morgan M, Williams R, Riva A, Chokshi Set al., 2019, Type III interferon lambda derangements are associated with susceptibility to infection in alcohol-related liver disease, The International Liver Congress™ EASL - European Association for the Study of the Liver

Conference paper

Tyson LD, Atkinson S, Pechlivanis A, Holmes E, Vergis N, Nathwani R, Maurice J, Taylor-Robinson S, Mullish BH, Williams R, McPhail MJW, Patel V, Thursz Met al., 2019, Serum bile acid profiles distinguish severe alcoholic hepatitis from decompensated alcohol-related cirrhosis, International Liver Congress, Publisher: ELSEVIER SCIENCE BV, Pages: E108-E108, ISSN: 0168-8278

Conference paper

Tyson LD, Lewis H, 2019, How I treat. . . alcohol-related liver disease, CLINICAL MEDICINE, Vol: 19, Pages: 43-46, ISSN: 1470-2118

Journal article

Beckett VL, Tyson LD, Carroll D, Gooding NM, Kelsall AWet al., 2012, Accurately administering oral medication to children isn't child's play, ARCHIVES OF DISEASE IN CHILDHOOD, Vol: 97, Pages: 838-841, ISSN: 0003-9888

Journal article

Barraud P, Seferiadis AA, Tyson LD, Zwart MF, Szabo-Rogers HL, Ruhrberg C, Liu KJ, Baker CVHet al., 2010, Neural crest origin of olfactory ensheathing glia, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 107, Pages: 21040-21045, ISSN: 0027-8424

Journal article

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