Louise is a Lecturer in the Chemistry Department and a Group Leader at the Francis Crick Institute.
Louise obtained her PhD in chemical biology from the University of Oxford in 2014 under the supervision of Prof. Chris Schofield and Prof. Christina Redfield. She used a combination of biochemical and structural techniques to study the structure and function of ‘reader’ and ‘eraser’ proteins involved in epigenetics.
Following further postdoctoral work in Oxford, she obtained a Global Marie Skłodowska-Curie Fellowship to work in Japan for two years in the laboratory of Hiroaki Suga at the University of Tokyo, with a return year in Chris Schofield’s laboratory at the University of Oxford. In 2018, she established her lab at the Francis Crick Institute in a joint appointment with the Chemistry Department at Imperial College London.
et al., 2023, mRNA display reveals a class of high-affinity bromodomain-binding motifs that are not found in the human proteome., J Biol Chem, Vol:299
Williams J, Walport L, 2023, PADI6: What we know about the elusive fifth member of the peptidyl arginine deiminase family, Philosophical Transactions of the Royal Society B: Biological Sciences, Vol:378, ISSN:0962-8436
et al., 2023, Discovery and characterization of cyclic peptides selective for the C-terminal bromodomains of BET family proteins, Structure, Vol:31, ISSN:0969-2126, Pages:912-923.e4
et al., 2023, Identification of photocrosslinking peptide ligands by mRNA display, Communications Chemistry, Vol:6, ISSN:2399-3669, Pages:1-9
et al., 2021, The characterization of protein interactions - what, how and how much?, Chemical Society Reviews, Vol:50, ISSN:0306-0012, Pages:12292-12307