Imperial College London

Dr Laura Nicolaou

Faculty of EngineeringDepartment of Mechanical Engineering

Academic Visitor



+44 (0)20 7595 7112laura.nicolaou Website




609City and Guilds BuildingSouth Kensington Campus





Laura is a Research Fellow in the Department of Mechanical Engineering at Imperial College London. Her research activity focuses on numerical and mathematical modelling of particle-laden flows with particular focus on human health and the environment. Research interests include inhaled drug delivery, ambient and indoor air pollution, airborne disease transmission, and the development of numerical algorithms for high-fidelity, large-scale computations of complex physiological flows. Her work on pulmonary drug delivery and air pollution relies on 3D computational fluid dynamics simulations and 1D whole-lung models to develop new understanding of the deposition of inhaled particles in the lungs.


Imperial College London

  • PhD in Computational Fluid Dynamics, A robust immersed boundary method for flow in complex geometries: Study of aerosol deposition in the human extrathoracic airways, 2012
  • MEng in Mechanical Engineering, 2007

Selected Publications

Journal Articles

Nicolaou L, Checkley W, 2021, Differences between cigarette smoking and biomass smoke exposure: An in silico comparative assessment of particulate deposition in the lungs, Environmental Research, Vol:197, ISSN:0013-9351, Pages:111116-111116

Nicolaou L, Checkley W, 2021, Inequities in air pollution exposure and gaps in air quality monitoring, Journal of Allergy and Clinical Immunology, ISSN:0091-6749

Nicolaou L, Fandiño‐Del‐Rio M, Koehler K, et al., 2021, Size distribution and lung‐deposited doses of particulate matter from household exposure to biomass smoke, Indoor Air, Vol:31, ISSN:0905-6947, Pages:51-62

Singanayagam A, Zhou J, Elderfield RA, et al., 2020, Characterising viable virus from air exhaled by H1N1 influenza-infected ferrets reveals the importance of haemagglutinin stability for airborne infectivity, PLOS Pathogens, Vol:16, ISSN:1553-7366, Pages:1-21

Nicolaou L, 2018, Inertial and gravitational effects on aerosol deposition in the conducting airways, Journal of Aerosol Science, Vol:120, ISSN:0021-8502, Pages:32-51

Koullapis P, Nicolaou L, Kassinos SC, 2018, In silico assessment of mouth-throat effects on regional deposition in the upper tracheobronchial airways, Journal of Aerosol Science, Vol:117, ISSN:0021-8502, Pages:164-188

Koullapis P, Kassinos SC, Muela J, et al., 2017, Regional aerosol deposition in the human airways: the SimInhale benchmark case and a critical assessment of in silico methods, European Journal of Pharmaceutical Sciences, Vol:113, ISSN:0928-0987, Pages:77-94

Nicolaou L, Zaki TA, 2016, Characterization of aerosol Stokes number in 90◦ bends and idealized extrathoracic airways, Journal of Aerosol Science, Vol:102, ISSN:0021-8502, Pages:105-127

Nicolaou L, Jung SY, Zaki TA, 2015, A robust direct-forcing immersed boundary method with enhanced stability for moving body problems in curvilinear coordinates, Computers & Fluids, Vol:119, ISSN:0045-7930, Pages:101-114

Nicolaou L, Zaki TA, 2012, Direct numerical simulations of flow in realistic mouth–throat geometries, Journal of Aerosol Science, Vol:57, ISSN:1879-1964, Pages:71-87

More Publications