Imperial College London
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Dr Lucia M. Li

Faculty of Medicine, Department of Brain Sciences

Clinical Lecturer (Neurology)
 
 
 
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Contact

 

lucia.li

 
 
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Location

 

Burlington DanesHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Varatharaj:2020:10.1016/S2215-0366(20)30287-X,
author = {Varatharaj, A and Thomas, N and Ellul, MA and Davies, NWS and Pollak, TA and Tenorio, EL and Sultan, M and Easton, A and Breen, G and Zandi, M and Coles, JP and Manji, H and Al-Shahi, Salman R and Menon, DK and Nicholson, TR and Benjamin, LA and Carson, A and Smith, C and Turner, MR and Solomon, T and Kneen, R and Pett, SL and Galea, I and Thomas, RH and Michael, BD and CoroNerve, Study Group},
doi = {10.1016/S2215-0366(20)30287-X},
journal = {Lancet Psychiatry},
pages = {875--882},
title = {Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study.},
url = {http://dx.doi.org/10.1016/S2215-0366(20)30287-X},
volume = {7},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BACKGROUND: Concerns regarding potential neurological complications of COVID-19 are being increasingly reported, primarily in small series. Larger studies have been limited by both geography and specialty. Comprehensive characterisation of clinical syndromes is crucial to allow rational selection and evaluation of potential therapies. The aim of this study was to investigate the breadth of complications of COVID-19 across the UK that affected the brain. METHODS: During the exponential phase of the pandemic, we developed an online network of secure rapid-response case report notification portals across the spectrum of major UK neuroscience bodies, comprising the Association of British Neurologists (ABN), the British Association of Stroke Physicians (BASP), and the Royal College of Psychiatrists (RCPsych), and representing neurology, stroke, psychiatry, and intensive care. Broad clinical syndromes associated with COVID-19 were classified as a cerebrovascular event (defined as an acute ischaemic, haemorrhagic, or thrombotic vascular event involving the brain parenchyma or subarachnoid space), altered mental status (defined as an acute alteration in personality, behaviour, cognition, or consciousness), peripheral neurology (defined as involving nerve roots, peripheral nerves, neuromuscular junction, or muscle), or other (with free text boxes for those not meeting these syndromic presentations). Physicians were encouraged to report cases prospectively and we permitted recent cases to be notified retrospectively when assigned a confirmed date of admission or initial clinical assessment, allowing identification of cases that occurred before notification portals were available. Data collected were compared with the geographical, demographic, and temporal presentation of overall cases of COVID-19 as reported by UK Government public health bodies. FINDINGS: The ABN portal was launched on April 2, 2020, the BASP portal on April 3, 2020, and the RCPsych portal on April 21, 2020
AU  - Varatharaj,A
AU  - Thomas,N
AU  - Ellul,MA
AU  - Davies,NWS
AU  - Pollak,TA
AU  - Tenorio,EL
AU  - Sultan,M
AU  - Easton,A
AU  - Breen,G
AU  - Zandi,M
AU  - Coles,JP
AU  - Manji,H
AU  - Al-Shahi,Salman R
AU  - Menon,DK
AU  - Nicholson,TR
AU  - Benjamin,LA
AU  - Carson,A
AU  - Smith,C
AU  - Turner,MR
AU  - Solomon,T
AU  - Kneen,R
AU  - Pett,SL
AU  - Galea,I
AU  - Thomas,RH
AU  - Michael,BD
AU  - CoroNerve,Study Group
DO  - 10.1016/S2215-0366(20)30287-X
EP  - 882
PY  - 2020///
SP  - 875
TI  - Neurological and neuropsychiatric complications of COVID-19 in 153 patients: a UK-wide surveillance study.
T2  - Lancet Psychiatry
UR  - http://dx.doi.org/10.1016/S2215-0366(20)30287-X
UR  - https://www.ncbi.nlm.nih.gov/pubmed/32593341
VL  - 7
ER  -
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