Imperial College London

Dr Lucia M. Li

Faculty of MedicineDepartment of Brain Sciences

Clinical Lecturer (Neurology)
 
 
 
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Contact

 

lucia.li

 
 
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Location

 

Burlington DanesHammersmith Campus

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Summary

 

Publications

Citation

BibTex format

@article{Li:2015:10.3389/fncel.2015.00181,
author = {Li, LM and Uehara, K and Hanakawa, T},
doi = {10.3389/fncel.2015.00181},
journal = {Frontiers in Cellular Neuroscience},
title = {The contribution of interindividual factors to variability of response in transcranial direct current stimulation studies},
url = {http://dx.doi.org/10.3389/fncel.2015.00181},
volume = {9},
year = {2015}
}

RIS format (EndNote, RefMan)

TY  - JOUR
AB - There has been an explosion of research using transcranial direct current stimulation (tDCS) for investigating and modulating human cognitive and motor function in healthy populations. It has also been used in many studies seeking to improve deficits in disease populations. With the slew of studies reporting “promising results” for everything from motor recovery after stroke to boosting memory function, one could be easily seduced by the idea of tDCS being the next panacea for all neurological ills. However, huge variability exists in the reported effects of tDCS, with great variability in the effect sizes and even contradictory results reported. In this review, we consider the interindividual factors that may contribute to this variability. In particular, we discuss the importance of baseline neuronal state and features, anatomy, age and the inherent variability in the injured brain. We additionally consider how interindividual variability affects the results of motor-evoked potential (MEP) testing with transcranial magnetic stimulation (TMS), which, in turn, can lead to apparent variability in response to tDCS in motor studies.
AU - Li,LM
AU - Uehara,K
AU - Hanakawa,T
DO - 10.3389/fncel.2015.00181
PY - 2015///
SN - 1662-5102
TI - The contribution of interindividual factors to variability of response in transcranial direct current stimulation studies
T2 - Frontiers in Cellular Neuroscience
UR - http://dx.doi.org/10.3389/fncel.2015.00181
UR - http://hdl.handle.net/10044/1/31959
VL - 9
ER -