4 results found
Al-Qaisi M, Nott DM, King DH, et al., 2009, Imaging of peripheral vascular disease, Reports in Imaging, Pages: 1-10
Al-Qaisi M, Nott DM, King DH, et al., 2009, Ankle brachial pressure index (ABPI): An update for practitioners., Vasc Health Risk Manag, Vol: 5, Pages: 833-841
Peripheral vascular disease affects some 12%-14% of the general population, and the majority of people with the disease are asymptomatic. The ankle brachial pressure index (ABPI) test is widely used by a diverse range of practitioners (in the community and hospital setting) in order to screen asymptomatic patients, diagnose patients with clinical symptoms, and to monitor patients who have had radiological or surgical intervention. This paper explains the theoretical basis of the ABPI test, as well as the relevance of the common modifications of the test. It explores the background to the quoted normal ranges for the ABPI test. It reviews the large body of literature that has developed on the association between ABPI and cardiovascular risk, as well as ABPI as a predictor for cardiovascular morbidity and mortality, highlighting the evidence that can inform practice. The review looks critically at the limitations of the ABPI test, providing practitioners with an evidence-based update on the importance and challenges of standardizing ABPI methodology. This paper highlights the influence of the key technical aspects of the ABPI test that all practitioners need to consider in order to be able to make more reliable and informed management decisions based on ABPI findings.
Al-Qaisi M, Kharbanda RK, Mittal TK, et al., 2008, Measurement of endothelial function and its clinical utility for cardiovascular risk., Vasc Health Risk Manag, Vol: 4, Pages: 647-652, ISSN: 1176-6344
Over the past two decades, the central role of the endothelium in the initiation, progression, and clinical sequelae of atherosclerosis has been increasingly recognized. Assessment of the pathobiology of the endothelium and its ability to act as a potential therapeutic target remains an area of active research interest. Whilst endothelial function has been shown to be a marker for risk of cardiovascular events in high-risk groups, there remains considerable debate about the most appropriate way to assess this. We discuss the different clinical methods to assess endothelial function, focusing on flow-mediated dilatation (FMD) of the brachial artery, highlighting the importance of using a standardized methodology, as well as discussing the clinical limitations of using FMD in individuals.
Al-Qaisi M, Deane C, Goss DE, et al., 2007, Clinical audit. An update for ultrasound practitioners, Ultrasound, Vol: 15, Pages: 236-239
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