Dr Bahmanyar received his PhD from Brunel University in 2006. He has been doing research at the interface of engineering/physics with medicine for sixteen years developing medical devices including working with manufactures and regulators. He joined the Institute of Biomedical Engineering in 2009. Currently, he directs research on ocular implants and cardiovascular devices; also is part of a team, funded by the Wellcome Trust and the Department of Health to develop a complete implant system for a phase I clinical trial for pulmonary artery blood pressure monitoring. His research has attracted significant commercial interest from Imperial innovations and external investors.
Implantable SAW Transponder for Acute and Chronic Blood Pressure Monitoring
Many cardiovascular and respiratory diseases cause blood pressure changes in the chambers of the heart and the vessels linking the heart and lungs. Measuring such localised pressures has had to rely either on inaccurate external measurements or otherwise performed very intermittently by expensive and somewhat risky catheterisations. As a research fellow and the co-investigator, I specifically work on the design and fabrication of implantable antennas, SAW sensors, RF interrogation system and algorithm development. This includes close collaboration with regulators and companies in the US and Europe to develop patient safe medical devices suitable for our planned clinical trial.
Development of a novel prototype catheterised lithotripsy device for enhanced treatment of calcific coronary artery disease
Coronary artery disease is one of the commonest clinical conditions associated with high morbidity and mortality in developed countries. It is often treated by percutaneous coronary intervention (PCI); one of the most common therapeutic interventional procedures performed anywhere. Coronary calcification is an inherent element of atherosclerotic coronary disease and presents significant challenges to PCI. We have prototyped a novel low-profile device which can be delivered as an over-the-wire microcatheter into even challenging coronary anatomies.
Development of an Easily Deployable Intraocular Wireless Pressure Sensing Implant for Patients with Rapidly Progressing and Blinding Glaucoma
Glaucoma is the commonest cause of irreversible blindness in the world. It affects about 4% of the population over 40 years of age, and being asymptomatic, is often diagnosed late. Currently all therapies aim at lowering the intraocular pressure (IOP), but assessment of patients’ IOP is performed using static, single or infrequent measurements whereas significant IOP variation occurs between clinical visits and even at different times of day.
I am directing the research; also working on the design of implant components to develop an IOP wireless sensor that can be implanted in patients in a clinical outpatient setting to provide frequent measurement of IOP to monitor instantaneous, diurnal and trend values directly without requiring clinical or complex patient procedures.
A pilot study of the diagnostic potential of low frequency sound recorded from cardiac muscle
In collaboration with cardiologists at Glenfield hospital in Leicester, we are currently running a pilot clinical study to assess the diagnostic potential of heart sound in conjunction with ECG.