Imperial College London


Faculty of MedicineSchool of Public Health

Chair in Biostatistics



m.blangiardo Website




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BibTex format

author = {Halonen, JI and Dehbi, HM and Hansell, AL and Gulliver, J and Fecht, D and Blangiardo, M and Kelly, FJ and Chaturvedi, N and Kivimäki, M and Tonne, C},
doi = {10.1016/j.envint.2016.09.023},
journal = {Environment International},
pages = {54--61},
title = {Associations of night-time road traffic noise with carotid intima-media thickness and blood pressure: The Whitehall II and SABRE study cohorts},
url = {},
volume = {98},
year = {2016}

RIS format (EndNote, RefMan)

AB - BACKGROUND: Road traffic noise has been linked to increased risk of stroke, for which hypertension and carotid intima-media thickness (cIMT) are risk factors. A link between traffic noise and hypertension has been established, but there are few studies on blood pressure and no studies on cIMT. OBJECTIVES: To examine cross-sectional associations for long-term exposure to night-time noise with cIMT, systolic blood pressure (SBP), diastolic blood pressure (DBP) and hypertension. METHODS: The study population consisted of 2592 adults from the Whitehall II and SABRE cohort studies living within Greater London who had cIMT, SBP and DBP measured. Exposure to night-time road traffic noise (A-weighted dB, referred to as dBA) was estimated at each participant's residential postcode centroid. RESULTS: Mean night-time road noise levels were 52dBA (SD=4). In the pooled analysis adjusted for cohort, sex, age, ethnicity, marital status, smoking, area-level deprivation and NOx there was a 9.1μm (95% CI: -7.1, 25.2) increase in cIMT in association with 10dBA increase in night-time noise. Analyses by noise categories of 55-60dBA (16.2μm, 95% CI: -8.7, 41.2), and >60dBA (21.2μm, 95% CI: -2.5, 44.9) vs. <55dBA were also positive but non-significant, expect among those not using antihypertensive medication and exposed to >60dBA vs. <55dBA (32.6μm, 95% CI: 6.2, 59.0). Associations for SBP, DPB and hypertension were close to null. CONCLUSIONS: After adjustments, including for air pollution, the association between night-time road traffic noise and cIMT was only observed among non-medication users but associations with blood pressure and hypertension were largely null.
AU - Halonen,JI
AU - Dehbi,HM
AU - Hansell,AL
AU - Gulliver,J
AU - Fecht,D
AU - Blangiardo,M
AU - Kelly,FJ
AU - Chaturvedi,N
AU - Kivimäki,M
AU - Tonne,C
DO - 10.1016/j.envint.2016.09.023
EP - 61
PY - 2016///
SN - 0160-4120
SP - 54
TI - Associations of night-time road traffic noise with carotid intima-media thickness and blood pressure: The Whitehall II and SABRE study cohorts
T2 - Environment International
UR -
UR -
VL - 98
ER -