Imperial College London
Alternate

ProfessorMartaBlangiardo

Faculty of Medicine, School of Public Health

Chair in Biostatistics
 
 
 
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Contact

 

m.blangiardo Website

 
 
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Location

 

705School of Public HealthWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Konstantinoudis:2022:10.1136/thoraxjnl-2021-218374,
author = {Konstantinoudis, G and Cosetta, M and Vicedo, Cabrera AM and Ballester, J and Gasparrini, A and Blangiardo, M},
doi = {10.1136/thoraxjnl-2021-218374},
journal = {Thorax},
pages = {1098--1104},
title = {Ambient heat exposure and COPD hospitalisations in England: a nationwide case-crossover study during 2007-2018},
url = {http://dx.doi.org/10.1136/thoraxjnl-2021-218374},
volume = {77},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Background: There is emerging evidence suggesting a link between ambient heat exposure and chronic obstructive pulmonary disease (COPD) hospitalisations. Individual and contextual characteristics can affect population vulnerabilities to COPD hospitalisation due to heat exposure. This study quantifies the effect of ambient heat on COPD hospitalisations and examines population vulnerabilities by age, sex and contextual characteristics.Methods: Individual data on COPD hospitalisation at high geographical resolution (postcodes) during 2007–2018 in England was retrieved from the small area health statistics unit. Maximum temperature at 1 km ×1 km resolution was available from the UK Met Office. We employed a case-crossover study design and fitted Bayesian conditional Poisson regression models. We adjusted for relative humidity and national holidays, and examined effect modification by age, sex, green space, average temperature, deprivation and urbanicity.Results: After accounting for confounding, we found 1.47% (95% Credible Interval (CrI) 1.19% to 1.73%) increase in the hospitalisation risk for every 1°C increase in temperatures above 23.2°C (lags 0–2 days). We reported weak evidence of an effect modification by sex and age. We found a strong spatial determinant of the COPD hospitalisation risk due to heat exposure, which was alleviated when we accounted for contextual characteristics. 1851 (95% CrI 1 576 to 2 079) COPD hospitalisations were associated with temperatures above 23.2°C annually.Conclusion: Our study suggests that resources should be allocated to support the public health systems, for instance, through developing or expanding heat-health alerts, to challenge the increasing future heat-related COPD hospitalisation burden.
AU  - Konstantinoudis,G
AU  - Cosetta,M
AU  - Vicedo,Cabrera AM
AU  - Ballester,J
AU  - Gasparrini,A
AU  - Blangiardo,M
DO  - 10.1136/thoraxjnl-2021-218374
EP  - 1104
PY  - 2022///
SN  - 0040-6376
SP  - 1098
TI  - Ambient heat exposure and COPD hospitalisations in England: a nationwide case-crossover study during 2007-2018
T2  - Thorax
UR  - http://dx.doi.org/10.1136/thoraxjnl-2021-218374
UR  - http://hdl.handle.net/10044/1/96712
VL  - 77
ER  -
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