Publications
215 results found
Carlucci F, Cortes-Hernandez J, Fossati-Jimack LM, et al., 2006, Genetic contribution of 129 chromosome 1 intervals to autoimmunity in C57BL/6 mice, BSR Annual Meeting/BHPR Spring Meeting, Publisher: OXFORD UNIV PRESS, Pages: I4-I4, ISSN: 1462-0324
Tas SW, Quartier P, Botto M, et al., 2006, Macrophages from patients with SLE and rheumatoid arthritis have defective adhesion in vitro, while only SLE macrophages have impaired uptake of apoptotic cells, ANNALS OF THE RHEUMATIC DISEASES, Vol: 65, Pages: 216-221, ISSN: 0003-4967
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- Citations: 100
Manderson AP, Carlucci F, Lachmann PJ, et al., 2006, The <i>in vivo</i> expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosus, ARTHRITIS RESEARCH & THERAPY, Vol: 8, ISSN: 1478-6354
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- Citations: 16
Trendelenburg M, Fossati-Jimack L, Cortes-Hernandez J, et al., 2005, The role of complement in cryoglobulin-induced immune complex glomerulonephritis, JOURNAL OF IMMUNOLOGY, Vol: 175, Pages: 6909-6914, ISSN: 0022-1767
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- Citations: 49
Giacomin PR, Wang H, Gordon DL, et al., 2005, Loss of complement activation and leukocyte adherence as <i>Nippostrongylus brasiliensis</i> develops within the murine host, INFECTION AND IMMUNITY, Vol: 73, Pages: 7442-7449, ISSN: 0019-9567
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- Citations: 25
Ten VS, Sosunov SA, Mazer SP, et al., 2005, C1q-deficiency is neuroprotective against hypoxic-ischemic brain injury in neonatal mice, STROKE, Vol: 36, Pages: 2244-2250, ISSN: 0039-2499
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- Citations: 68
Yuste J, Botto M, Paton JC, et al., 2005, Additive inhibition of complement deposition by pneumolysin and PspA facilitates <i>Streptococcus pneumoniae</i> septicemia, JOURNAL OF IMMUNOLOGY, Vol: 175, Pages: 1813-1819, ISSN: 0022-1767
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- Citations: 70
Botto M, 2005, What knockout mice have taught us about the pathogenesis of lupus, Annual European Congress of Rheumatology, Publisher: BMJ PUBLISHING GROUP, Pages: 53-53, ISSN: 0003-4967
Exley RM, Shaw J, Mowe E, et al., 2005, Available carbon source influences the resistance of <i>Neisseria meningitidis</i> against complement, JOURNAL OF EXPERIMENTAL MEDICINE, Vol: 201, Pages: 1637-1645, ISSN: 0022-1007
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- Citations: 73
Haskard DO, Bhatia V, Boyle JJ, et al., 2005, Role of complement and complement regulatory proteins in atherosclerosis, 75th Congress of the European-Atherosclerosis-Society, Publisher: ELSEVIER IRELAND LTD, Pages: 39-39, ISSN: 1567-5688
Monk CR, Spachidou M, Rovis F, et al., 2005, MRL/Mp CD4+,CD25-T cells show reduced sensitivity to suppression by CD4+,CD25+regulatory T cells in vitro - A novel defect of T cell regulation in systemic lupus erythematosus, ARTHRITIS AND RHEUMATISM, Vol: 52, Pages: 1180-1184, ISSN: 0004-3591
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- Citations: 101
Hepburn AL, Ng WF, Layton M, et al., 2005, In vivo evidence for apoptosis in the bone marrow in SLE, Joint Meeting of the British-Society-for-Rheumatology/Deutsche-Gesellschaft-fur-Rheumatologie and Spring Meeting of the British-Health-Professionals-in-Rheumatology, Publisher: OXFORD UNIV PRESS, Pages: I135-I135, ISSN: 1462-0324
Quartier P, Potter PK, Ehrenstein MR, et al., 2005, Predominant role of IgM-dependent activation of the classical pathway in the clearance of dying cells by murine bone marrow-derived macrophages <i>in vitro</i>, EUROPEAN JOURNAL OF IMMUNOLOGY, Vol: 35, Pages: 252-260, ISSN: 0014-2980
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- Citations: 123
Cortes-Hernandez J, Fossati-Jimack L, Petry F, et al., 2004, Restoration of C1q levels by bone marrow transplantation attenuates autoimmune disease associated with C1q deficiency in mice, EUROPEAN JOURNAL OF IMMUNOLOGY, Vol: 34, Pages: 3713-3722, ISSN: 0014-2980
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- Citations: 37
Stokol T, O'Donnell P, Xiao L, et al., 2004, C1q governs deposition of circulating immune complexes and leukocyte Fcγ receptors mediate subsequent neutrophil recruitment, JOURNAL OF EXPERIMENTAL MEDICINE, Vol: 200, Pages: 835-846, ISSN: 0022-1007
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- Citations: 50
Trendelenburg M, Manderson AP, Fossati-Jimack L, et al., 2004, Monocytosis and accelerated activation of lymphocytes in C1q-deficient autoimmune-prone mice, IMMUNOLOGY, Vol: 113, Pages: 80-88, ISSN: 0019-2805
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- Citations: 16
Turnberg D, Botto M, Lewis M, et al., 2004, CD59a deficiency exacerbates ischemia-reperfusion injury in mice, AMERICAN JOURNAL OF PATHOLOGY, Vol: 165, Pages: 825-832, ISSN: 0002-9440
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- Citations: 38
Bygrave AE, Rose KL, Cortes-Hernandez J, et al., 2004, Spontaneous autoimmunity in 129 and C57BL/6 mice - Implications for autoimmunity described in gene-targeted mice, PLOS BIOLOGY, Vol: 2, Pages: 1081-1090, ISSN: 1544-9173
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- Citations: 155
Fonseca MI, Zhou J, Botto M, et al., 2004, Absence of C1q leads to less neuropathology in transgenic mouse models of Alzheimer's disease, JOURNAL OF NEUROSCIENCE, Vol: 24, Pages: 6457-6465, ISSN: 0270-6474
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- Citations: 236
Hutchinson WL, Herbert J, Botto M, et al., 2004, Classical and alternative pathway complement activation are not required for reactive systemic AA amyloid deposition in mice, IMMUNOLOGY, Vol: 112, Pages: 250-254, ISSN: 0019-2805
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- Citations: 2
Norsworthy PJ, Fossati-Jimack L, Cortes-Hernandez J, et al., 2004, Murine CD93 (C1qRp) contributes to the removal of apoptotic cells in vivo but is not required for C1q-mediated enhancement of phagocytosis, JOURNAL OF IMMUNOLOGY, Vol: 172, Pages: 3406-3414, ISSN: 0022-1767
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- Citations: 113
Yamada M, Oritani K, Kaisho T, et al., 2004, Complement C1q regulates LPS-induced cytokine production in bone marrow-derived dendritic cells, EUROPEAN JOURNAL OF IMMUNOLOGY, Vol: 34, Pages: 221-230, ISSN: 0014-2980
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- Citations: 63
Mead RJ, Neal JW, Griffiths MR, et al., 2004, Deficiency of the complement regulator CD59a enhances disease severity, demyelination and axonal injury in murine acute experimental allergic encephalomyelitis, LABORATORY INVESTIGATION, Vol: 84, Pages: 21-28, ISSN: 0023-6837
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- Citations: 74
Botto M, 2004, Phosphatidylserine receptor and apoptosis: consequences of a non-ingested meal, Arthritis Research & Therapy, Vol: 6, Pages: 147-150
Manderson AP, Botto M, Walport MJ, 2004, The role of complement in the development of systemic lupus erythematosus, ANNUAL REVIEW OF IMMUNOLOGY, Vol: 22, Pages: 431-456, ISSN: 0732-0582
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- Citations: 374
Gillmore JD, Hutchinson WL, Mitchell DA, et al., 2003, Studies of serum amyloid P component (SAP) and antinuclear autoimmunity., 36th Annual Meeting of the American-Society-of-Nephrology, Publisher: AMER SOC NEPHROLOGY, Pages: 167A-168A, ISSN: 1046-6673
Turnberg D, Botto M, Warren J, et al., 2003, CD59a deficiency exacerbates adriamycin nephropathy and ischaemia-reperfusion injury in mice., 36th Annual Meeting of the American-Society-of-Nephrology, Publisher: LIPPINCOTT WILLIAMS & WILKINS, Pages: 163A-163A, ISSN: 1046-6673
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- Citations: 1
Stäger S, Alexander J, Kirby AC, et al., 2003, Natural antibodies and complement are endogenous adjuvants for vaccine-induced CD8<SUP>+</SUP> T-cell responses, NATURE MEDICINE, Vol: 9, Pages: 1287-1292, ISSN: 1078-8956
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- Citations: 171
Turnberg D, Botto M, 2003, The regulation of the complement system: insights from genetically-engineered mice, MOLECULAR IMMUNOLOGY, Vol: 40, Pages: 145-153, ISSN: 0161-5890
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- Citations: 45
Trendelenburg M, Hernandes-Cortes J, Walport SIMJ, et al., 2003, The role of complement in cryoglobulin-induced immune complex glomerulonephritis, 9th European Meeting on Complement in Human Disease, Publisher: PERGAMON-ELSEVIER SCIENCE LTD, Pages: 192-192, ISSN: 0161-5890
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