Imperial College London

Mr Mads Jarner Brevadt

Faculty of MedicineDepartment of Surgery & Cancer

Honorary Research Associate







7L16Lab BlockCharing Cross Campus





Publication Type

3 results found

Jones G, Kotti M, Wiik A, Collins R, Brevadt M, Strachan R, Cobb Jet al., 2016, Gait comparison of unicompartmental and total knee arthroplasties with healthy controls, Bone & Joint Journal, Vol: 98-B, Pages: 16-21, ISSN: 2049-4394

Aims:To compare the gait of unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) patients with healthy controls, usinga machine learning approach.Patients:145 participants (121 healthy controls, 12 cruciate retaining TKA patients, and 12 mobile bearing UKA patients) were recruited. The TKAand UKA patients were a minimum of 12 months post-op, and matched for pattern and severity of arthrosis, age, and BMI.Methods:Participants walked on an instrumented treadmill until their maximum walking speed was reached. Temporospatial gait parameters, andvertical ground reaction force data was captured at each speed. Oxford knee scores (OKS) were also collected. An ensemble of treesalgorithm was used to analyse the data: 27 gait variables were used to train classification trees for each speed, with a binary outputprediction of whether these variables were derived from a UKA or TKA patient. Healthy control gait data was then tested by the decisiontrees at each speed and a final classification (UKA or TKA) reached for each subject in a majority voting manner over all gait cycles andspeeds. Top walking speed was also recorded.Results:92% of the healthy controls were classified by the decision tree as a UKA, 5% as a TKA, and 3% were unclassified. There was nosignificant difference in OKS between the UKA and TKA patients (p=0.077). Top walking speed in TKA patients (1.6 m/s [1.3-2.1]) wassignificantly lower than that of both the UKA group (2.2 m/s [1.8-2.7]) and healthy controls (2.2 m/s [1.5-2.7]) (p<0.001).Conclusion:UKA results in a more physiological gait compared to TKA, and a higher top walking speed. This difference in function was not detectedby the OKS.

Journal article

Manning V, Yiallourides C, Brevadt M, Moore A, Auvinet E, Naylor P, Cobb Jet al., 2015, Knee sounds may predict osteoarthritis severity, symptoms and function: pilot investigation toward a novel dynamic imaging system, Arthritis & Rheumatology, Vol: 67, ISSN: 2326-5191

Journal article

Brevadt MJ, manning VL, wiik A, aqil A, dadia S, cobb JPet al., 2015, THE IMPACT OF STEM LENGTH ON FUNCTION FOLLOWING HIP ARTHROPLASTY: ARE LONG STEMS STILL REQUIRED?, International Society for Technology in Arthroplasty

Conference paper

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