Imperial College London
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Professor M Francesca Cordeiro

Faculty of Medicine, Department of Surgery & Cancer

Chair in Ophthalmology (Clinical)
 
 
 
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Contact

 

m.cordeiro

 
 
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Location

 

Norfolk PlaceSt Mary's Campus

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Summary

 

Publications

Citation

BibTex format

@article{Abdulhussein:2022,
author = {Abdulhussein, D and Yap, T and Manzer, H and Miodragovic, S and Cordeiro, M},
journal = {Trials},
pages = {1--9},
title = {Factors impacting participation in research during the COVID-19 pandemic},
url = {https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-022-06748-1},
volume = {23},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BackgroundUnderstanding public and patient attitudes to clinical research is paramount to successful recruitment. The COVID-19 pandemic has led to additional hurdles in achieving this. Our aim is to understand the current factors and attitudes towards clinical trial participation in order to assist in recruitment to clinical trials.MethodsWe conducted face-to-face interviews with patients in the outpatient department at a tertiary eye hospital facilitated by a 32-item questionnaire developed by the research team. Patient characteristics were correlated with their responses, in addition to qualitative thematic text analysis.ResultsA total of 53 patients were interviewed. Forty per cent indicated that they would be willing to participate in clinical research in the current climate. General motivating factors for involvement in research included personal gain, altruism and contribution to innovation. Factors limiting participation included concerns regarding own safety, inconvenience, accessibility and lack of benefit. 22.6% of participants felt that the COVID-19 pandemic has changed their outlook on research. These were categorised into positive (increased awareness of the importance and need for research, altruism) and negative (increased anxiety, need to minimise exposure to the hospital environment) influences.ConclusionsFactors influencing patients’ decisions to participate in trials are similar to those observed prior to COVID-19 but with an increased focus on the environment the research is conducted in. The COVID-19 pandemic has had positive and negative impacts on patient attitudes towards research. Trial design, with a particular focus on setting and safety measures, in reassuring patients is increasingly important.
AU  - Abdulhussein,D
AU  - Yap,T
AU  - Manzer,H
AU  - Miodragovic,S
AU  - Cordeiro,M
EP  - 9
PY  - 2022///
SN  - 1745-6215
SP  - 1
TI  - Factors impacting participation in research during the COVID-19 pandemic
T2  - Trials
UR  - https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-022-06748-1
UR  - http://hdl.handle.net/10044/1/99840
VL  - 23
ER  -
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