Imperial College London
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Professor Mark R. Crimmin

Faculty of Natural Sciences, Department of Chemistry

Professor of Organometallic Chemistry
 
 
 
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Contact

 

+44 (0)20 7594 2846m.crimmin Website

 
 
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Location

 

501NMolecular Sciences Research HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Mulryan:2020:10.1021/acs.orglett.0c03593,
author = {Mulryan, D and White, AJP and Crimmin, MR},
doi = {10.1021/acs.orglett.0c03593},
journal = {Organic Letters},
pages = {9351--9355},
title = {Organocatalyzed fluoride metathesis},
url = {http://dx.doi.org/10.1021/acs.orglett.0c03593},
volume = {22},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - A new organocatalyzed fluoride metathesis reaction between fluoroarenes and carbonyl derivatives is reported. The reaction exchanges fluoride (F–) and alternate nucleophiles (OAc–, OCO2R–, SR–, Cl–, CN–, NCS–). The approach provides a conceptually novel route to manipulate the fluorine content of organic molecules. When the fluorination and defluorination steps are combined into a single catalytic cycle, a byproduct free and 100% atom-efficient reaction can be achieved.
AU  - Mulryan,D
AU  - White,AJP
AU  - Crimmin,MR
DO  - 10.1021/acs.orglett.0c03593
EP  - 9355
PY  - 2020///
SN  - 1523-7060
SP  - 9351
TI  - Organocatalyzed fluoride metathesis
T2  - Organic Letters
UR  - http://dx.doi.org/10.1021/acs.orglett.0c03593
UR  - https://pubs.acs.org/doi/10.1021/acs.orglett.0c03593
UR  - http://hdl.handle.net/10044/1/84422
VL  - 22
ER  -
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