Imperial College London
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Professor Mark R. Crimmin

Faculty of Natural Sciences, Department of Chemistry

Professor of Organometallic Chemistry
 
 
 
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Contact

 

+44 (0)20 7594 2846m.crimmin Website

 
 
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Location

 

501NMolecular Sciences Research HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Crimmin:2020:10.26434/chemrxiv.12901304.v1,
author = {Crimmin, M and Mulryan, D and White, AJP},
doi = {10.26434/chemrxiv.12901304.v1},
title = {Organocatalyzed Fluoride Metathesis},
url = {http://dx.doi.org/10.26434/chemrxiv.12901304.v1},
year = {2020}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - <jats:p>A new organocatalyzed fluoride metathesis reaction between fluoroarenes and carbonyl derivatives is reported. The reaction exchanges fluoride (F–) and alternate nucleophiles (OAc–, CO2R–, SR–, Cl–, CN–, NCS–). The approach provides a conceptually novel route to manipulate the fluorine content of organic molecules. By combining fluorination and defluorination steps into a single catalytic cycle, a byproduct free and 100% atom-efficient reaction can be achieved.</jats:p>
AU  - Crimmin,M
AU  - Mulryan,D
AU  - White,AJP
DO  - 10.26434/chemrxiv.12901304.v1
PY  - 2020///
TI  - Organocatalyzed Fluoride Metathesis
UR  - http://dx.doi.org/10.26434/chemrxiv.12901304.v1
ER  -
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