Cell Biology and Genetics - LIFE40006
The behaviour of living cells is influenced by both their genetics and by their environment. In this module, you will explore how the genetic information in cells is expressed as a phenotype, and how this expression is regulated in response to stimuli from the cell's environment. The module will address the central information transfer pathways in the cell (replication, transcription and translation), and aims to develop your skills in analysing genetic systems in model organisms. It will familiarise you with the compartments from which eukaryotic cells are constructed and how proteins are targeted to them. We will also explore specific examples of cellular interactions: neuronal signalling, vertebrate immunity, and viral infection. In the practical work in the summer term, you will work as a team to design experiments to investigate your own hypotheses in the context of the interaction between the growth of bacterial cells and their environment. We will continue to develop both your quantitative and writing skills.
Neuroscience Research - LIFE96026
This course will show how some of the basic concepts and principles of biophysics can be applied to the mammalian nervous system to gain an understanding of how neurons function. It will then show how this information can be utilised to aid understanding of complex neuronal processing with relevance to human health, learning and memory. The course will be based around three advanced topics, each consisting of several related lectures and research seminars. The course will begin with an overview of the electrical properties of neurons and go on to explore the central roles that ion channels play in health and disease.