I am a Professor of Practice and Consultant Histopathologist at the Department of Histopathology, Imperial College London, Hammersmith Campus. My main area of practice and interest is Gynaecologic pathology, and in particular Gynaecological tumour pathology.
My job at Imperial College is a reflection of the ethos of the Academic Health Sciences Centre, where service work, teaching and research work are complimentary.
My research focuses on the identification of diagnostic and prognostic biomarkers and potential therapeutic targets for epithelial tumours, particularly gynaecological tumours. I have special interest in borderline ovarian tumours and sex cord stromal tumours. Recently published work from our laboratory shows that there are molecular subtypes of serous borderline ovarian tumours. Continued work in this area will hopefully lead to the identification of predictive biomarkers for the biological behaviour of individual borderline tumours, as well as the identification of potential therapeutic targets for tumours showing aggressive behaviour; both of which remain to be unmet clinical needs.
et al., Toxic shock syndrome toxin-1 evaluation and antibiotic impact in a transgenic model of staphylococcal soft tissue infection, Msphere, ISSN:2379-5042
et al., 2019, A combination of the immunohistochemical markers CK7 and SATB2 is highly sensitive and specific for distinguishing primary ovarian mucinous tumors from colorectal and appendiceal metastases., Mod Pathol
et al., 2019, SHOC2 phosphatase-dependent RAF dimerization mediates resistance to MEK inhibition in RAS-mutant cancers, Nature Communications, Vol:10, ISSN:2041-1723
et al., 2019, Targeted next generation sequencing of pancreatic solid pseudopapillary neoplasms show mutations in Wnt signaling pathway genes, Pathology International, ISSN:1320-5463
et al., 2019, Sex hormone, insulin, and insulin-like growth factor signaling in recurrence of high stage endometrial cancer: Results from the NRG Oncology/Gynecologic Oncology Group 210 trial., Annual Meeting of the American-Society-of-Clinical-Oncology (ASCO), AMER SOC CLINICAL ONCOLOGY, ISSN:0732-183X