I am an Adjunct Reader and Consultant histopathologist at the Department of Histopathology, Imperial College London, Hammersmith Campus. My main area of practice and interest is Gynaecologic pathology, and in particular Gynaecological tumour pathology.
My job at Imperial College is a reflection of the ethos of the Academic Health Sciences Centre, where service work, teaching and research work are complimentary.
My research focuses on the identification of diagnostic and prognostic biomarkers and potential therapeutic targets for epithelial tumours, particularly gynaecological tumours. I have special interest in borderline ovarian tumours. Recently published work from our laboratory shows that there are molecular subtypes of serous borderline ovarian tumours. Continued work in this area will hopefully lead to the identification of predictive biomarkers for the biological behaviour of individual borderline tumours, as well as the identification of potetial therapeutic targets for tumours showing agressive behaviour; both of which remain to be unmet clinical needs.
et al., 2019, SHOC2 phosphatase-dependent RAF dimerization mediates resistance to MEK inhibition in RAS-mutant cancers., Nat Commun, Vol:10
et al., 2019, Targeted next generation sequencing of pancreatic solid pseudopapillary neoplasms show mutations in Wnt signaling pathway genes, Pathology International, ISSN:1320-5463
et al., 2019, Superficial myofibroblastoma of the genital tract: a case report of the imaging findings, Bjr Case Reports, Vol:5, ISSN:2055-7159
et al., 2018, Anti-tumour activity of a first-in-class agent NUC-1031 in patients with advanced cancer: results of a phase I study, British Journal of Cancer, Vol:119, ISSN:0007-0920, Pages:815-822
et al., 2018, Association of p16 expression with prognosis varies across ovarian carcinoma histotypes: an Ovarian Tumor Tissue Analysis consortium study, Journal of Pathology: Clinical Research, ISSN:2056-4538