Summary
Dr Mike Emerson is a Reader in Platelet Pharmacology in the Vascular Science Section of the National Heart and Lung Institute. He is Head of the Platelet Biology Group based at the Hammersmith site and is Director of Student Tutoring in the School of Medicine.
The Platelet Biology Group focuses on the application of platelet science at multi-disciplinary interfaces. We investigate interactions of platelets with antiretroviral drugs and explore changes in platelet and endothelial function in people living with HIV to understand increased cardiovascular risk in this cohort. We are also interested in interactions between platelets and nanomaterials in order to develop and evaluate new therapies such as haemostatic medical devices and we explore the effects of nanoparticulate pollution upon cardiovascular health.
Within the School of Medicine, Dr Emerson heads up the Academic Tutoring programme to work with undergraduate medical students and coach them to develop effective and efficient learning skills as well as promoting wellbeing. He is a recipient of a Rector's Medal for Excellence in Pastoral Care and a President's Award for Supporting the Student Experience.
Dr Emerson studied Animal Physiology and Nutrition at the University of Leeds and obtained a PhD from King’s College London in 1998. His PhD thesis defined the antithrombotic role of endogenous nitric oxide in vivo. He then embarked upon several post-doctoral positions and worked at the Universities of Sydney, Edinburgh and Manchester.
Selected Publications
Journal Articles
Khawaja AA, Taylor KA, Lovell AO, et al., 2020, HIV antivirals affect endothelial activation and endothelial-platelet crosstalk., Circulation Research, Vol:127, ISSN:0009-7330, Pages:1365-1380
Taylor KA, Smyth E, Rauzi F, et al., 2019, Pharmacological impact of antiretroviral therapy on platelet function to investigate HIV-associated cardiovascular risk, British Journal of Pharmacology, Vol:176, ISSN:0007-1188, Pages:879-889
Smyth E, Solomon A, Birrell MA, et al., 2017, Influence of inflammation and nitric oxide upon platelet aggregation following deposition of diesel exhaust particles in the airways., British Journal of Pharmacology, Vol:174, ISSN:0007-1188, Pages:2130-2139
Apostoli GL, Solomon A, Smallwood MJ, et al., 2014, Role of inorganic nitrate and nitrite in driving nitric oxide-GMP-mediated inhibition of platelet aggregation in vitro and in vivo, Journal of Thrombosis and Haemostasis, Vol:12, ISSN:1538-7933, Pages:1880-1889
Mohamed TMA, Oceandy D, Zi M, et al., 2011, Plasma Membrane Calcium Pump (PMCA4)-Neuronal Nitric-oxide Synthase Complex Regulates Cardiac Contractility through Modulation of a Compartmentalized Cyclic Nucleotide Microdomain, Journal of Biological Chemistry, Vol:286, ISSN:0021-9258, Pages:41520-41529