DrMarioFalchi

Faculty of Medicine, Department of Immunology and Inflammation

Honorary Senior Research Fellow

Contact

+44 (0)20 7594 6519m.falchi

Location

Burlington-Danes Building, Room E303Hammersmith HospitalHammersmith Campus

Summary

Software

famCNV - copy number variant association for quantitative traits in families

The program uses intensity signals (aCGH and SNP genotyping data) which act as proxies for genomic copy number to carry out association with quantitative traits in family settings.

Download the program famCNV
source files

Documentation famCNV manual and example file famCNV example files

Aranea - Differential network analysis for high-throughput ‘omics data

Aranea is an open-source multi-threaded package for the differential network analysis of large datasets.

Download the program Aranea
Documentation Aranea_Doc and example files Aranea Examples

Publications

Journals

Visconti A, Rossi N, Deris H, et al.Visconti A, Rossi N, Deris H, Lee KA, Hanic M, Trbojevic-Akmacic I, Thomas AM, Bolte LA, Bjork JR, Hooiveld-Noeken JS, Board R, Harland M, Newton-Bishop J, Harries M, Sacco JJ, Lorigan P, Shaw HM, de Vries EGE, Fehrmann RSN, Weersma RK, Spector TD, Nathan P, Hospers GAP, Sasieni P, Bataille V, Lauc G, Falchi M close, 2023, Total serum N-glycans associate with response to immune checkpoint inhibition therapy and survival in patients with advanced melanoma, Bmc Cancer, Vol:23

Valles-Colomer M, Blanco-Míguez A, Manghi P, et al.Valles-Colomer M, Blanco-Míguez A, Manghi P, Asnicar F, Dubois L, Golzato D, Armanini F, Cumbo F, Huang KD, Manara S, Masetti G, Pinto F, Piperni E, Punčochář M, Ricci L, Zolfo M, Farrant O, Goncalves A, Selma-Royo M, Binetti AG, Becerra JE, Han B, Lusingu J, Amuasi J, Amoroso L, Visconti A, Steves CM, Falchi M, Filosi M, Tett A, Last A, Xu Q, Qin N, Qin H, May J, Eibach D, Corrias MV, Ponzoni M, Pasolli E, Spector TD, Domenici E, Collado MC, Segata N close, 2023, The person-to-person transmission landscape of the gut and oral microbiomes., Nature, Vol:614, Pages:125-135

Zhang X, Adebayo AS, Wang D, et al.Zhang X, Adebayo AS, Wang D, Raza Y, Tomlinson M, Dooley H, Bowyer RCE, Small KS, Steves CJ, Spector TD, Duncan EL, Visconti A, Falchi M close, 2022, PPI-Induced Changes in Plasma Metabolite Levels Influence Total Hip Bone Mineral Density in a UK Cohort, Journal of Bone and Mineral Research, ISSN:0884-0431

Surendran P, Stewart ID, Yeung VPWA, et al.Surendran P, Stewart ID, Yeung VPWA, Pietzner M, Raffler J, Worheide MA, Li C, Smith RF, Wittemans LBL, Bomba L, Menni C, Zierer J, Rossi N, Sheridan PA, Watkins NA, Mangino M, Hysi PG, Di Angelantonio E, Falchi M, Spector TD, Soranzo N, Michelotti GA, Arlt W, Lotta LA, Denaxas S, Hemingway H, Gamazon ER, Howson JMM, Wood AM, Danesh J, Wareham NJ, Kastenmueller G, Fauman EB, Suhre K, Butterworth AS, Langenberg C close, 2022, Rare and common genetic determinants of metabolic individuality and their effects on human health, Nature Medicine, Vol:28, ISSN:1078-8956, Pages:2321-2332

Coradduzza D, Solinas T, Balzano F, et al.Coradduzza D, Solinas T, Balzano F, Culeddu N, Rossi N, Cruciani S, Azara E, Maioli M, Zinellu A, De Miglio MR, Madonia M, Falchi M, Carru C close, 2022, miRNAs as Molecular Biomarkers for Prostate Cancer, Journal of Molecular Diagnostics, Vol:24, ISSN:1525-1578, Pages:1171-1180

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