Imperial College London

DrMarioFalchi

Faculty of MedicineDepartment of Immunology and Inflammation

Honorary Senior Research Fellow
 
 
 
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Contact

 

+44 (0)20 7594 6519m.falchi

 
 
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Location

 

Burlington-Danes Building, Room E303Hammersmith HospitalHammersmith Campus

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Summary

 

Publications

Publication Type
Year
to

128 results found

Le Roy CI, Kurilshikov A, Leeming ER, Visconti A, Bowyer RCE, Menni C, Fachi M, Koutnikova H, Veiga P, Zhernakova A, Derrien M, Spector TDet al., 2022, Yoghurt consumption is associated with changes in the composition of the human gut microbiome and metabolome, BMC MICROBIOLOGY, Vol: 22, ISSN: 1471-2180

Journal article

Hysi PG, Mangino M, Christofidou P, Falchi M, Karoly ED, Mohney RP, Valdes AM, Spector TD, Menni Cet al., 2022, Metabolome Genome-Wide Association Study Identifies 74 Novel Genomic Regions Influencing Plasma Metabolites Levels, METABOLITES, Vol: 12

Journal article

Grosche S, Marenholz I, Esparza-Gordillo J, Arnau-Soler A, Pairo-Castineira E, Rueschendorf F, Ahluwalia TS, Almqvist C, Arnold A, Baurecht H, Bisgaard H, Bonnelykke K, Brown SJ, Bustamante M, Curtin JA, Custovic A, Dharmage SC, Esplugues A, Falchi M, Fernandez-Orth D, Ferreira MAR, Franke A, Gerdes S, Gieger C, Hakonarson H, Holt PG, Homuth G, Hubner N, Hysi PG, Jarvelin M-R, Karlsson R, Koppelman GH, Lau S, Lutz M, Magnusson PKE, Marks GB, Mueller-Nurasyid M, Noethen MM, Paternoster L, Pennell CE, Peters A, Rawlik K, Robertson CF, Rodriguez E, Sebert S, Simpson A, Sleiman PMA, Standl M, Stoelzl D, Strauch K, Szwajda A, Tenesa A, Thompson PJ, Ullemar V, Visconti A, Vonk JM, Wang CA, Weidinger S, Wielscher M, Worth CL, Xu C-J, Lee Y-Aet al., 2021, Rare variant analysis in eczema identifies exonic variants in DUSP1, NOTCH4 and SLC9A4, NATURE COMMUNICATIONS, Vol: 12

Journal article

Cvetko A, Mangino M, Tijardovic M, Kifer D, Falchi M, Keser T, Perola M, Spector TD, Lauc G, Menni C, Gornik Oet al., 2021, Plasma N-glycome shows continuous deterioration as the diagnosis of insulin resistance approaches, BMJ OPEN DIABETES RESEARCH & CARE, Vol: 9

Journal article

Dotz V, Visconti A, Lomax-Browne HJ, Clerc F, Hipgrave Ederveen AL, Medjeral-Thomas NR, Cook HT, Pickering MC, Wuhrer M, Falchi Met al., 2021, O- and N-glycosylation of serum immunoglobulin A is associated with IgA nephropathy and glomerular function., Journal of the American Society of Nephrology, Vol: 32, Pages: 1-12, ISSN: 1046-6673

BACKGROUND: IgA nephropathy (IgAN) is the most common primary glomerular disease worldwide and is a leading cause of renal failure. The disease mechanisms are not completely understood, but a higher abundance of galactose-deficient IgA is recognized to play a crucial role in IgAN pathogenesis. Although both types of human IgA (IgA1 and IgA2) have several N-glycans as post-translational modification, only IgA1 features extensive hinge-region O-glycosylation. IgA1 galactose deficiency on the O-glycans is commonly detected by a lectin-based method. To date, limited detail is known about IgA O- and N-glycosylation in IgAN. METHODS: To gain insights into the complex O- and N-glycosylation of serum IgA1 and IgA2 in IgAN, we used liquid chromatography-mass spectrometry (LC-MS) for the analysis of tryptic glycopeptides of serum IgA from 83 patients with IgAN and 244 age- and sex-matched healthy controls. RESULTS: Multiple structural features of N-glycosylation of IgA1 and IgA2 were associated with IgAN and glomerular function in our cross-sectional study. These features included differences in galactosylation, sialylation, bisection, fucosylation, and N-glycan complexity. Moreover, IgA1 O-glycan sialylation was associated with both the disease and glomerular function. Finally, glycopeptides were a better predictor of IgAN and glomerular function than galactose-deficient IgA1 levels measured by lectin-based ELISA. CONCLUSIONS: Our high-resolution data suggest that IgA O- and N-glycopeptides are promising targets for future investigations on the pathophysiology of IgAN and as potential noninvasive biomarkers for disease prediction and deteriorating kidney function.

Journal article

Hopkinson N, Rossi N, El-Sayed Moustafa JS, Laverty A, Quint J, Freidin MB, Visconti A, Murray B, Modat M, Ourselin S, Small K, Davies R, Wolf J, Spector TD, Steves CJ, Falchi Met al., 2021, Current smoking and COVID-19 risk: results from a population symptom app in over 2.4 million people, Thorax, Vol: 76, Pages: 714-722, ISSN: 0040-6376

Background: The association between current tobacco smoking, the risk of developing symptomatic COVID-19 and the severity of illness is an important information gap.Methods: UK users of the Zoe COVID Symptom Study App provided baseline data including demographics, anthropometrics, smoking status and medical conditions, and were asked to log their condition daily. Participants who reported that they did not feel physically normal were then asked by the app to complete a series of questions, including 14 potential COVID-19 symptoms and about hospital attendance. The main study outcome was the development of “classic” symptoms of COVID-19 during the pandemic defined as fever, new persistent cough and breathlessness and their association with current smoking. The number of concurrent COVID-19 symptoms was used as a proxy for severity and the pattern of association between symptoms was also compared between smokers and non-smokers. Results: Between 24th March 2020 to 23rd April 2020, data were available on 2,401,982 participants, mean(SD) age 43.6(15.1) years, 63.3% female, overall smoking prevalence 11.0%. 834,437 (35%) participants reported being unwell and entered one or more symptoms. Current smokers were more likely to report symptoms suggesting a diagnosis of COVID-19; classic symptoms adjusted OR[95%CI] 1.14[1.10 to 1.18]; >5 symptoms 1.29[1.26 to 1.31]; >10 symptoms 1.50[1.42 to 1.58]. The pattern of association between reported symptoms did not vary between smokers and non-smokers.Interpretation: These data are consistent with people who smoke being at an increased risk of developing symptomatic COVID-19.

Journal article

Greto VL, Cvetko A, Stambuk T, Dempster NJ, Kifer D, Deris H, Cindric A, Vuckovic F, Falchi M, Gillies RS, Tomlinson JW, Gornik O, Sgromo B, Spector TD, Menni C, Geremia A, Arancibia-Carcamo CV, Lauc Get al., 2021, Extensive weight loss reduces glycan age by altering IgG N-glycosylation, INTERNATIONAL JOURNAL OF OBESITY, Vol: 45, Pages: 1521-1531, ISSN: 0307-0565

Journal article

Sanna M, Li X, Visconti A, Freidin MB, Sacco C, Ribero S, Hysi P, Bataille V, Han J, Falchi Met al., 2021, Looking for Sunshine: Genetic Predisposition to Sun Seeking in 265,000 Individuals of European Ancestry, JOURNAL OF INVESTIGATIVE DERMATOLOGY, Vol: 141, Pages: 779-786, ISSN: 0022-202X

Journal article

Piaggeschi G, Rolla S, Rossi N, Brusa D, Naccarati A, Couvreur S, Spector TD, Roederer M, Mangino M, Cordero F, Falchi M, Visconti Aet al., 2021, Immune Trait Shifts in Association With Tobacco Smoking: A Study in Healthy Women, FRONTIERS IN IMMUNOLOGY, Vol: 12, ISSN: 1664-3224

Journal article

Visconti A, Bataille V, Rossi N, Kluk J, Murphy R, Puig S, Nambi R, Bowyer RCE, Murray B, Bournot A, Wolf J, Ourselin S, Steves CJ, Spector TD, Falchi Met al., 2021, Diagnostic value of cutaneous manifestation of SARS-CoV-2 infection, BRITISH JOURNAL OF DERMATOLOGY, Vol: 184, Pages: 880-887, ISSN: 0007-0963

Journal article

Sudre CH, Lee KA, Lochlainn MN, Varsavsky T, Murray B, Graham MS, Menni C, Modat M, Bowyer RCE, Nguyen LH, Drew DA, Joshi AD, Ma W, Guo C-G, Lo C-H, Ganesh S, Buwe A, Pujol JC, du Cadet JL, Visconti A, Freidin MB, Moustafa JSE-S, Falchi M, Davies R, Gomez MF, Fall T, Cardoso MJ, Wolf J, Franks PW, Chan AT, Spector TD, Steves CJ, Ourselin Set al., 2021, Symptom clusters in COVID-19: A potential clinical prediction tool from the COVID Symptom Study app, SCIENCE ADVANCES, Vol: 7, ISSN: 2375-2548

Journal article

Rossi N, Aliyev E, Visconti A, Akil ASA, Syed N, Aamer W, Padmajeya SS, Falchi M, Fakhro KAet al., 2021, Ethnic-specific association of amylase gene copy number with adiposity traits in a large Middle Eastern biobank, NPJ GENOMIC MEDICINE, Vol: 6

Journal article

Patasova K, Khawaja AP, Tamraz B, Williams KM, Mahroo OA, Freidin M, Solebo AL, Vehof J, Falchi M, Rahi JS, Hammond CJ, Hysi PGet al., 2021, Association Between Medication-Taking and Refractive Error in a Large General Population-Based Cohort, INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Vol: 62, ISSN: 0146-0404

Journal article

He J-W, Zhou X-J, Li Y-F, Wang Y-N, Liu L-J, Shi S-F, Xin X-H, Li R-S, Falchi M, Lv J-C, Zhang Het al., 2021, Associations of Genetic Variants Contributing to Gut Microbiota Composition in Immunoglobin A Nephropathy, MSYSTEMS, Vol: 6, ISSN: 2379-5077

Journal article

Williams FMK, Freidin MB, Mangino M, Couvreur S, Visconti A, Bowyer RCE, Le Roy CI, Falchi M, Mompeo O, Sudre C, Davies R, Hammond C, Menni C, Steves CJ, Spector TDet al., 2020, Self-Reported Symptoms of COVID-19, Including Symptoms Most Predictive of SARS-CoV-2 Infection, Are Heritable, TWIN RESEARCH AND HUMAN GENETICS, Vol: 23, Pages: 316-321, ISSN: 1832-4274

Journal article

Bar N, Korem T, Weissbrod O, Zeevi D, Rothschild D, Leviatan S, Kosower N, Lotan-Pompan M, Weinberger A, Le Roy CI, Menni C, Visconti A, Falchi M, Spector TD, Adamski J, Franks PW, Pedersen O, Segal Eet al., 2020, A reference map of potential determinants for the human serum metabolome, NATURE, Vol: 588, Pages: 135-140, ISSN: 0028-0836

Journal article

Bataille V, Visconti A, Rossi N, Murray B, Bournot A, Wolf J, Ourselin S, Steves C, Spector TD, Falchi Met al., 2020, Diagnostic value of skin manifestation of SARS-CoV-2 infection

<jats:title>Abstract</jats:title><jats:p>SARS-CoV-2 causes multiple immune-related reactions at various stages of the disease. The wide variety of skin presentations has delayed linking these to the virus. Previous studies had attempted to look at the prevalence and timing of SARS-COV-2 rashes but were based on mostly hospitalized severe cases and had little follow up. Using data collected on a subset of 336,847 eligible UK users of the COVID Symptom Study app, we observed that 8.8% of the swab positive cases (total: 2,021 subjects) reported either a body rash or an acral rash, compared to 5.4% of those with a negative swab test (total: 25,136). Together, these two skin presentations showed an odds ratio (OR) of 1.67 (95% confidence interval [CI]: 1.41-1.96) for being swab positive. Skin rashes were also predictive in the larger untested group of symptomatic app users (N=54,652), as 8.2% of those who had reported at least one classical COVID-19 symptom, <jats:italic>i</jats:italic>.<jats:italic>e</jats:italic>., fever, persistent cough, and/or anosmia, also reported a rash. Data from an independent online survey of 11,546 respondents with a rash showed that in 17% of swab positive cases, the rash was the initial presentation. Furthermore, in 21%, the rash was the only clinical sign. Skin rashes cluster with other COVID-19 symptoms, are predictive of a positive swab test and occur in a significant number of cases, either alone or before other classical symptoms. Recognising rashes is important in identifying new and earlier COVID-19 cases.</jats:p>

Journal article

Menni C, Valdes AM, Freidin MB, Sudre CH, Nguyen LH, Drew DA, Ganesh S, Varsavsky T, Cardoso MJ, Moustafa JSE-S, Visconti A, Hysi P, Bowyer RCE, Mangino M, Falchi M, Wolf J, Ourselin S, Chan AT, Steves CJ, Spector TDet al., 2020, Real-time tracking of self-reported symptoms to predict potential COVID-19, NATURE MEDICINE, Vol: 26, Pages: 1037-+, ISSN: 1078-8956

Journal article

Visconti A, Sanna M, Bataille V, Falchi Met al., 2020, Genetics plays a role in nevi distribution in women, MELANOMA MANAGEMENT, Vol: 7, Pages: 3-6, ISSN: 2045-0885

Journal article

Greto VL, Cvetko A, Štambuk T, Dempster NJ, Kifer D, Deriš H, Cindrić A, Vučković F, Falchi M, Gillies RS, Tomlinson JW, Gornik O, Sgromo B, Spector TD, Menni C, Geremia A, Arancibia-Cárcamo CV, Lauc Get al., 2020, Extensive weight loss can reduce immune age by altering IgG N-glycosylation

<jats:title>ABSTRACT</jats:title><jats:sec><jats:title>Background</jats:title><jats:p>Obesity is a major global health problem, and is associated with increased cardiometabolic morbidity and mortality. Protein glycosylation is a frequent postranslational modification, highly responsive to numerous pathophysiological conditions and ageing. The prospect of biological age reduction, by reverting glycosylation changes through metabolic intervention, opens many possibilities. We have investigated whether weight loss interventions affect inflammation- and ageing-associated IgG glycosylation changes, in a longitudinal cohort of bariatric surgery patients. To support potential findings, BMI-related glycosylation changes were monitored in a longitudinal twins cohort.</jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p>IgG N-glycans were chromatographically profiled in 37 obese patients, subjected to low-calorie diet, followed by bariatric surgery, across multiple timepoints. Similarly, plasma-derived IgG N-glycan traits were longitudinally monitored in 1,680 participants from the TwinsUK cohort.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Low-calorie diet induced a marked decrease in the levels of IgG N-glycans with bisecting GlcNAc, whose higher levels are usually associated with ageing and inflammatory conditions. Bariatric surgery resulted in extensive alterations of the IgG glycome that accompanied progressive weight loss during one-year follow-up. We observed a significant increase in digalactosylated and sialylated glycans, and a substantial decrease in agalactosylated and core fucosylated IgG glycans. In general, this IgG glycan profile is associated with a younger biological age and reflects an enhanced anti-inflammatory IgG potential. Loss of BMI over a 20 year period in the TwinsUK cohort validated a weight loss-assoc

Journal article

Landi MT, Bishop DT, MacGregor S, Machiela MJ, Stratigos AJ, Ghiorzo P, Brossard M, Calista D, Choi J, Fargnoli MC, Zhang T, Rodolfo M, Trower AJ, Menin C, Martinez J, Hadjisavvas A, Song L, Stefanaki I, Scolyer R, Yang R, Goldstein AM, Potrony M, Kypreou KP, Pastorino L, Queirolo P, Pellegrini C, Cattaneo L, Zawistowski M, Gimenez-Xavier P, Rodriguez A, Elefanti L, Manoukian S, Rivoltini L, Smith BH, Loizidou MA, Del Regno L, Massi D, Mandala M, Khosrotehrani K, Akslen LA, Amos C, Andresen PA, Avril M-F, Azizi E, Soyer HP, Bataille V, Dalmasso B, Bowdler LM, Burdon KP, Chen W, Codd V, Craig JE, Debniak T, Falchi M, Fang S, Friedman E, Simi S, Galan P, Garcia-Casado Z, Gillanders EM, Gordon S, Green A, Gruis NA, Hansson J, Harland M, Harris J, Helsing P, Henders A, Hocevar M, Hoiom V, Hunter D, Ingvar C, Kumar R, Lang J, Lathrop GM, Lee JE, Li X, Lubinski J, Mackie RM, Malt M, Malvehy J, McAloney K, Mohamdi H, Molven A, Moses EK, Neale RE, Novakovic S, Nyholt DR, Olsson H, Orr N, Fritsche LG, Anton Puig-Butille J, Qureshi AA, Radford-Smith GL, Randerson-Moor J, Requena C, Rowe C, Samani NJ, Sanna M, Schadendorf D, Schulze H-J, Simms LA, Smithers M, Song F, Swerdlow AJ, van der Stoep N, Kukutsch NA, Visconti A, Wallace L, Ward S, Wheeler L, Sturm RA, Hutchinson A, Jones K, Malasky M, Vogt A, Zhou W, Pooley KA, Elder DE, Han J, Hicks B, Hayward NK, Kanetsky PA, Brummett C, Montgomery GW, Olsen CM, Hayward C, Dunning AM, Martin NG, Evangelou E, Mann GJ, Long G, Pharoah PDP, Easton DF, Barrett JH, Cust AE, Abecasis G, Duffy DL, Whiteman DC, Gogas H, De Nicolo A, Tucker MA, Newton-Bishop JA, Peris K, Chanock SJ, Demenais F, Brown KM, Puig S, Nagore E, Shi J, Iles MM, Law MHet al., 2020, Genome-wide association meta-analyses combining multiple risk phenotypes provide insights into the genetic architecture of cutaneous melanoma susceptibility, Nature Genetics, Vol: 52, Pages: 494-504, ISSN: 1061-4036

Most genetic susceptibility to cutaneous melanoma remains to be discovered. Meta-analysis genome-wide association study (GWAS) of 36,760 cases of melanoma (67% newly genotyped) and 375,188 controls identified 54 significant (P < 5 × 10−8) loci with 68 independent single nucleotide polymorphisms. Analysis of risk estimates across geographical regions and host factors suggests the acral melanoma subtype is uniquely unrelated to pigmentation. Combining this meta-analysis with GWAS of nevus count and hair color, and transcriptome association approaches, uncovered 31 potential secondary loci for a total of 85 cutaneous melanoma susceptibility loci. These findings provide insights into cutaneous melanoma genetic architecture, reinforcing the importance of nevogenesis, pigmentation and telomere maintenance, together with identifying potential new pathways for cutaneous melanoma pathogenesis.

Journal article

Williams FMK, Freidin MB, Mangino M, Couvreur S, Visconti A, Bowyer RCE, Le Roy CI, Falchi M, Sudre C, Davies R, Hammond C, Menni C, Steves CJ, Spector TDet al., 2020, Self-reported symptoms of covid-19 including symptoms most predictive of SARS-CoV-2 infection, are heritable

<jats:title>Abstract</jats:title><jats:p>Susceptibility to infection such as SARS-CoV-2 may be influenced by host genotype. TwinsUK volunteers (n=2633) completing the C-19 Covid symptom tracker app allowed classical twin studies of covid-19 symptoms including predicted covid-19, a symptom-based algorithm predicting true infection derived in app users tested for SARS-CoV-2. We found heritability for fever = 41 (95% confidence intervals 12-70)%; anosmia 47 (27-67)%; delirium 49 (24-75)%; and predicted covid-19 gave heritability = 50 (29-70)%.</jats:p>

Journal article

Menni C, Valdes AM, Freidin MB, Ganesh S, El-Sayed Moustafa JS, Visconti A, Hysi P, Bowyer RCE, Mangino M, Falchi M, Wolf J, Steves CJ, Spector TDet al., 2020, Loss of smell and taste in combination with other symptoms is a strong predictor of COVID-19 infection

<jats:title>Abstract</jats:title><jats:sec><jats:title>Importance</jats:title><jats:p>A strategy for preventing further spread of the ongoing COVID-19 epidemic is to detect infections and isolate infected individuals without the need of extensive bio-specimen testing.</jats:p></jats:sec><jats:sec><jats:title>Objectives</jats:title><jats:p>Here we investigate the prevalence of loss of smell and taste among COVID-19 diagnosed individuals and we identify the combination of symptoms, besides loss of smell and taste, most likely to correspond to a positive COVID-19 diagnosis in non-severe cases.</jats:p></jats:sec><jats:sec><jats:title>Design</jats:title><jats:p>Community survey.</jats:p></jats:sec><jats:sec><jats:title>Setting and Participants</jats:title><jats:p>Subscribers of RADAR COVID-19, an app that was launched for use among the UK general population asking about COVID-19 symptoms.</jats:p></jats:sec><jats:sec><jats:title>Main Exposure</jats:title><jats:p>Loss of smell and taste.</jats:p></jats:sec><jats:sec><jats:title>Main Outcome Measures</jats:title><jats:p>COVID-19.</jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p>Between 24 and 29 March 2020, 1,573,103 individuals reported their symptoms via the app; 26% reported suffering from one or more symptoms of COVID-19. Of those, n=1702 reported having had a RT-PCR COVID-19 test and gave full report on symptoms including loss of smell and taste; 579 were positive and 1123 negative. In this subset, we find that loss of smell and taste were present in 59% of COVID-19 positive individuals compared to 18% of those negative to the test, yielding an odds ratio (OR) of COVID-19 diagnosis of OR[95%CI]=6.59[5.25; 8.27], P= 1.90×10<jats:sup>&minus

Journal article

Visconti A, Ribero S, Sanna M, Spector TD, Bataille V, Falchi Met al., 2020, Body site-specific genetic effects influence naevus count distribution in women, PIGMENT CELL & MELANOMA RESEARCH, Vol: 33, Pages: 326-333, ISSN: 1755-1471

Journal article

Verdi S, Abbasian G, Bowyer RCE, Lachance G, Yarand D, Christofidou P, Mangino M, Menni C, Bell JT, Falchi M, Small KS, Williams FMK, Hammond CJ, Hart DJ, Spector TD, Steves CJet al., 2019, TwinsUK: The UK Adult Twin Registry Update, TWIN RESEARCH AND HUMAN GENETICS, Vol: 22, Pages: 523-529, ISSN: 1832-4274

Journal article

Visconti A, Le Roy CI, Rosa F, Rossi N, Martin TC, Mohney RP, Li W, de Rinaldis E, Bell JT, Venter JC, Nelson KE, Spector TD, Falchi Met al., 2019, Interplay between the human gut microbiome and host metabolism, NATURE COMMUNICATIONS, Vol: 10, ISSN: 2041-1723

Journal article

Suhre K, Trbojevic-Akmacic I, Ugrina I, Mook-Kanamori DO, Spector T, Graumann J, Lauc G, Falchi Met al., 2019, Fine-Mapping of the Human Blood Plasma N-Glycome onto Its Proteome, METABOLITES, Vol: 9

Journal article

Khamis A, Canouil M, Siddiq A, Crouch H, Falchi M, von Bulow M, Ehehalt F, Marselli L, Distler M, Richter D, Weitz J, Bokvist K, Xenarios I, Thorens B, Schulte AM, Ibberson M, Bonnefond A, Marchetti P, Solimena M, Froguel Pet al., 2019, Laser capture microdissection of human pancreatic islets reveals novel eQTLs associated with type 2 diabetes, MOLECULAR METABOLISM, Vol: 24, Pages: 98-107, ISSN: 2212-8778

Journal article

Duffy DL, Zhu G, Li X, Sanna M, Iles MM, Jacobs LC, Evans DM, Yazar S, Beesley J, Law MH, Kraft P, Visconti A, Taylor JC, Liu F, Wright MJ, Henders AK, Bowdler L, Glass D, Ikram MA, Uitterlinden AG, Madden PA, Heath AC, Nelson EC, Green AC, Chanock S, Barrett JH, Brown MA, Hayward NK, MacGregor S, Sturm RA, Hewitt AW, Kayser M, Hunter DJ, Bishop JAN, Spector TD, Montgomery GW, Mackey DA, Smith GD, Nijsten TE, Bishop DT, Bataille V, Falchi M, Han J, Martin NG, Lee JE, Brossard M, Moses EK, Song F, Kumar R, Easton DF, Pharoah PDP, Swerdlow AJ, Kypreou KP, Harland M, Randerson-Moor J, Akslen LA, Andresen PA, Avril M-F, Azizi E, Scarra GB, Brown KM, Debniak T, Elder DE, Fang S, Friedman E, Galan P, Ghiorzo P, Gillanders EM, Goldstein AM, Gruis NA, Hansson J, Helsing P, Hocevar M, Hoiom V, Ingvar C, Kanetsky PA, Chen WV, Landi MT, Lang J, Lathrop GM, Lubinski J, Mackie RM, Mann GJ, Molven A, Novakovic S, Olsson H, Puig S, Puig-Butille JA, Radford-Smith GL, van der Stoep N, van Doorn R, Whiteman DC, Craig JE, Schadendorf D, Simms LA, Burdon KP, Nyholt DR, Pooley KA, Orr N, Stratigos AJ, Cust AE, Ward SV, Schulze H-J, Dunning AM, Demenais F, Amos CIet al., 2019, Novel pleiotropic risk loci for melanoma and nevus density implicate multiple biological pathways (vol 9, 4774, 2018), NATURE COMMUNICATIONS, Vol: 10, ISSN: 2041-1723

Journal article

Schena FP, Serino G, Sallustio F, Falchi M, Cox SNet al., 2018, Omics studies for comprehensive understanding of immunoglobulin A nephropathy: state-of-the-art and future directions, NEPHROLOGY DIALYSIS TRANSPLANTATION, Vol: 33, Pages: 2101-2112, ISSN: 0931-0509

Journal article

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