Imperial College London
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Prof Michael Fertleman

Faculty of Engineering, Department of Bioengineering

Professor of Practice
 
 
 
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Contact

 

+44 (0)20 7594 9046m.fertleman

 
 
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Location

 

6.24Sir Michael Uren HubWhite City Campus

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Summary

 

Publications

Citation

BibTex format

@article{Varma:2022:10.1007/s40520-022-02119-7,
author = {Varma, S and Wilson, MSJ and Naik, M and Sandhu, A and Ota, HCU and Aylwin, C and Fertleman, M and Peck, G},
doi = {10.1007/s40520-022-02119-7},
journal = {Aging Clinical and Experimental Research},
title = {The associations of psoas and masseter muscles with sarcopenia and related adverse outcomes in older trauma patients: a retrospective study},
url = {http://dx.doi.org/10.1007/s40520-022-02119-7},
volume = {34},
year = {2022}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - BackgroundThere is an emerging role for radiological evaluation of psoas muscle as a marker of sarcopenia in trauma patients. Older trauma patients are more likely to undergo cranial than abdomino-pelvic imaging. Identifying sarcopenia using masseter cross-sectional area (M-CSA) has shown correlation with mortality. We sought to determine the correlation between psoas: lumbar vertebral index (PLVI) and the M-CSA, and their association with health outcomes.MethodsPatients aged 65 or above, who presented as a trauma call over a 1-year period were included if they underwent cranial or abdominal CT imaging. Images were retrospectively analysed to obtain PLVI and mean M-CSA measurements. Electronic records were abstracted for outcomes. Logistic regression methods, log scale analyses, Cox regression model and Kaplan–Meier plots were used to determine association of sarcopenia with outcomes.ResultsThere were 155 eligible patients in the M-CSA group and 204 patients in the PLVI group. Sarcopenia was defined as the lowest quartile in each group. Pearson’s correlation indicated a weakly positive linear relationship (r = 0.35, p < 0.001) between these. There was no statistical association between M-CSA sarcopenia status and any measured outcomes. Those with PLVI sarcopenia were more likely to die in hospital (adjusted OR 3.38, 95% CI 1.47–9.73, p = 0.006) and at 2 years (adjusted HR 1.90, 95% CI 1.11–3.25, p = 0.02). Only 29% patients with PLVI sarcopenia were discharged home, compared with 58% without sarcopenia (p = 0.001).ConclusionSarcopenia, defined by PLVI, is predictive of increased in-patient and 2-year mortality. Our study did not support prognostic relevance of M-CSA.
AU  - Varma,S
AU  - Wilson,MSJ
AU  - Naik,M
AU  - Sandhu,A
AU  - Ota,HCU
AU  - Aylwin,C
AU  - Fertleman,M
AU  - Peck,G
DO  - 10.1007/s40520-022-02119-7
PY  - 2022///
SN  - 1594-0667
TI  - The associations of psoas and masseter muscles with sarcopenia and related adverse outcomes in older trauma patients: a retrospective study
T2  - Aging Clinical and Experimental Research
UR  - http://dx.doi.org/10.1007/s40520-022-02119-7
UR  - https://link.springer.com/article/10.1007/s40520-022-02119-7
UR  - http://hdl.handle.net/10044/1/96165
VL  - 34
ER  -
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