Imperial College London
Alternate

DrMarkFriddin

Faculty of Engineering, Dyson School of Design Engineering

Imperial College Research Fellow
 
 
 
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Contact

 

m.friddin

 
 
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Location

 

Dyson BuildingSouth Kensington Campus

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Summary

 

Publications

Citation

BibTex format

@article{Friddin:2019:10.1021/acs.analchem.8b04885,
author = {Friddin, MS and Elani, Y and Trantidou, T and Ces, O},
doi = {10.1021/acs.analchem.8b04885},
journal = {Analytical Chemistry},
pages = {4921--4928},
title = {New directions for artificial cells using rapid prototyped biosystems},
url = {http://dx.doi.org/10.1021/acs.analchem.8b04885},
volume = {91},
year = {2019}
}
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RIS format (EndNote, RefMan)

TY  - JOUR
AB  - Microfluidics has been shown to be capable of generating a range of single- and multi- compartment vesicles and bilayer delineated droplets that can be assembled in 2D and 3D. These model systems are becoming increasingly recognized as powerful biomimetic constructs for assembling tissue models, engineering therapeutic delivery systems and for screening drugs. One bottleneck in developing this technology is the time, expertise and equipment required for device fabrication. This has led to interest across the microfluidics community in using rapid prototyping to engineer microfluidic devices from Computer Aided Design (CAD) drawings. We highlight how this rapid prototyping revolution is transforming the fabrication of microfluidic devices for bottom-up synthetic biology. We provide an outline of the current landscape and present how advances in the field may give rise to the next generation of multifunctional biodevices, particularly with Industry 4.0 on the horizon. Successfully developing this technology and making it open-source could pave the way for a new generation of citizen-led science, fueling the possibility that the next multi-billion dollar start-up could emerge from an attic or a basement.
AU  - Friddin,MS
AU  - Elani,Y
AU  - Trantidou,T
AU  - Ces,O
DO  - 10.1021/acs.analchem.8b04885
EP  - 4928
PY  - 2019///
SN  - 0003-2700
SP  - 4921
TI  - New directions for artificial cells using rapid prototyped biosystems
T2  - Analytical Chemistry
UR  - http://dx.doi.org/10.1021/acs.analchem.8b04885
UR  - https://www.ncbi.nlm.nih.gov/pubmed/30841694
UR  - http://hdl.handle.net/10044/1/69070
VL  - 91
ER  -
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