Imperial College London

DrMatteoFumagalli

Faculty of Natural SciencesDepartment of Life Sciences (Silwood Park)

Lecturer in Quantitative Evolution
 
 
 
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Contact

 

+44 (0)20 7594 3793m.fumagalli

 
 
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Location

 

N1.6MunroSilwood Park

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Summary

 

Summary

The main focus of my research is population genetics, the study of genetic variation within species. The field is fundamental to understanding the genetic basis of adaptive traits, by elucidating the evolutionary forces that have shaped present-day genomic functional patterns. Population genomics approaches represent a valuable opportunity to address the evolutionary causes of modern complex diseases, by prioritising mutations for targeted association studies and functional experiments. I have developed and applied computational methods to highlight signatures of natural selection in the genome and to infer population demographic histories, by analysing large-scale datasets of model and non-model species. I have also designed and implemented software to analyse high-throughput sequencing data for evolutionary genomics purposes.

Publications

Journals

Adhikari K, Mendoza-Revilla J, Sohail A, et al., 2019, A GWAS in Latin Americans highlights the convergent evolution of lighter skin pigmentation in Eurasia, Nature Communications, Vol:10, ISSN:2041-1723

O'Hanlon SJ, Rieux A, Farrer RA, et al., 2018, Recent Asian origin of chytrid fungi causing global amphibian declines, Science, Vol:360, ISSN:0036-8075, Pages:621-+

Wright AE, Fumagalli M, Cooney CR, et al., 2018, Male-biased gene expression resolves sexual conflict through the evolution of sex-specific genetic architecture, Evolution Letters, Vol:2, ISSN:2056-3744, Pages:52-61

Elfekih S, Etter P, Tay WT, et al., 2018, Genome-wide analyses of the Bemisia tabaci species complex reveal contrasting patterns of admixture and complex demographic histories, Plos One, Vol:13, ISSN:1932-6203

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