Imperial College London

DrMatteoFumagalli

Faculty of Natural SciencesDepartment of Life Sciences (Silwood Park)

Lecturer in Quantitative Evolution
 
 
 
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Contact

 

+44 (0)20 7594 3793m.fumagalli

 
 
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Location

 

N1.6MunroSilwood Park

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Summary

 

Summary

The main focus of my research is population genetics, the study of genetic variation within species. The field is fundamental to understanding the genetic basis of adaptive traits, by elucidating the evolutionary forces that have shaped present-day genomic functional patterns. Population genomics approaches represent a valuable opportunity to address the evolutionary causes of modern complex diseases, by prioritising mutations for targeted association studies and functional experiments. I have developed and applied computational methods to highlight signatures of natural selection in the genome and to infer population demographic histories, by analysing large-scale datasets of model and non-model species. I have also designed and implemented software to analyse high-throughput sequencing data for evolutionary genomics purposes.

Publications

Journals

O'Hanlon SJ, Rieux A, Farrer RA, et al., 2018, Recent Asian origin of chytrid fungi causing global amphibian declines, Science, Vol:360, ISSN:0036-8075, Pages:621-+

Fumagalli M, Diekmann Y, Camus S, et al., 2018, The evolution of CHC22 clathrin influences its role in human glucose metabolism

Elfekih S, Etter P, Tay WT, et al., 2018, Genome-wide analyses of the Bemisia tabaci species complex reveal contrasting patterns of admixture and complex demographic histories, Plos One, Vol:13, ISSN:1932-6203

Lassalle F, Spagnoletti M, Fumagalli M, et al., 2018, Oral microbiomes from hunter-gatherers and traditional farmers reveal shifts in commensal balance and pathogen load linked to diet, Molecular Ecology, Vol:27, ISSN:0962-1083, Pages:182-195

Racimo F, Gokhman D, Fumagalli M, et al., 2017, Archaic Adaptive Introgression in TBX15/WARS2, Molecular Biology and Evolution, Vol:34, ISSN:0737-4038, Pages:509-524

More Publications