Summary
Malick Gibani is a Clinical Lecturer and Specialist Registrar in Infectious Diseases and Medical Microbiology. He completed his basic medical training at the University of Oxford, after which he continued his training in general medicine in London. He later joined the Oxford Vaccine Group in the Dept of Paediatrics, University of Oxford, where he undertook a DPhil with Andrew Pollard and Christine Rollier, focussing on the application of human challenge models to better understand pathogenesis and immunity to Salmonella Typhi and Paratyphi A. He has worked on a range of clinical vaccine trials including for Ebola, RSV and meningococcal disease.
Since 2019, he has worked as a clinical lecturer in the Department for Infectious Disease at Imperial College London. His research interests focus on the development of controlled human infection models and their application to accelerate vaccines for enteric diseases.
He is the PI on the Challenge Non-Typhoidal Salmonella (CHANTS) project, which aims to develop a new controlled human infection model for Salmonella Typhimurium.
https://www.imperial.ac.uk/infectious-disease/research/human-challenge/chants/
Publications
Journals
Baltas I, Kavallieros K, Konstantinou G, et al., 2024, The effect of ciprofloxacin prophylaxis during haematopoietic cell transplantation on infection episodes, exposure to treatment antimicrobials and antimicrobial resistance: a single-centre retrospective cohort study., Jac Antimicrob Resist, Vol:6
Cavaleri M, Kaslow D, Boateng E, et al., 2024, Fourth Controlled Human Infection Model (CHIM) meeting, CHIM regulatory issues, May 24, 2023., Biologicals, Vol:85
Smith C, Smith E, Rydlova A, et al., 2024, Protocol for the Challenge Nontyphoidal Salmonella (CHANTS) Study: a first-in-human, in-patient, double-blind, randomised, safety and dose-escalation controlled human infection model in the United Kingdom, Bmj Open, Vol:14, ISSN:2044-6055
Smith C, Smith E, Chiu C, et al., 2023, The Challenge Non-Typhoidal Salmonella (CHANTS) Consortium: Development of a non-typhoidal Salmonella controlled human infection model: Report from a consultation group workshop, 05 July 2022, London, UK [version 2; peer review: 2 approved], Wellcome Open Research, Vol:8, ISSN:2398-502X
Barton A, Hill J, O'Connor D, et al., 2023, Early transcriptional responses to human enteric fever challenge, Infection and Immunity, ISSN:0019-9567