As Divisional Mass Spectrometry (MS) and Chromatography Manager, I oversee the application of mature mass spectrometric methods and technologies to ongoing research initiatives within Computational and Systems Medicine (CSM), ensuring timely completion of project deliverables in the Clinical Phenotyping Centre (CPC) and the MRC-NIHR Phenome Centre (NPC).
When I started working in CSM as an honorary research associate in 2011, my research focused on the application of metabonomics to maternal pregnancy conditions and infants’ disease and development. After that, I was appointed as a research associate in the Division of Digestive Diseases looking after the projects arising from collaborations with CSM. Those projects were focused on the application of metabonomic techniques to diagnose and monitor liver cancer, alcoholic and viral hepatitis, hepatic encephalopathy and primary biliary cirrhosis, among other liver diseases. During that period, I also took on the role of LC-MS facility manager.
Prior to my time at Imperial College, I studied Chemical Engineering at the University of Granada (Spain) completing my final year design project on the production of titanium dioxide in University College London. Upon completing my BSc I undertook an MSc in Chemistry and my Ph.D. in Analytical Chemistry at the University of Granada, where I developed and evaluated analytical strategies (extraction, separation and detection mainly by MS) for the characterisation of phenolic compounds, and other metabolites, in different vegetable matrices.
et al., 2020, Performance of metabonomic serum analysis for diagnostics in paediatric tuberculosis., Sci Rep, Vol:10
et al., 2019, Enhanced microbial bile acid deconjugation and impaired ileal uptake in pregnancy repress intestinal regulation of bile acid synthesis, Hepatology, Vol:70, ISSN:0270-9139, Pages:276-293
et al., 2019, Breaking the cycle: reversal of flux in the tricarboxylic acid cycle by dimethyl fumarate, Neurology, Neuroimmunology and Neuroinflammation, Vol:6, ISSN:2332-7812
et al., 2018, The effects of kisspeptin on β-cell function, serum metabolites and appetite in humans, Diabetes, Obesity and Metabolism, Vol:20, ISSN:1462-8902, Pages:2800-2810
et al., 2018, Ultra performance liquid chromatography-high resolution mass spectrometry and direct infusion-high resolution mass spectrometry for combined exploratory and targeted metabolic profiling of human urine, Journal of Proteome Research, Vol:17, ISSN:1535-3893, Pages:3492-3502