Imperial College London

Mark Griffiths

Faculty of MedicineNational Heart & Lung Institute

Professor of Critical Care Medicine



m.griffiths Website




363Sir Alexander Fleming BuildingSouth Kensington Campus





Professor of Critical Care Medicine at the National Heart and Lung Institute and Consultant Physician at St Bartholomew's Hospital, London. Having qualified at London University in 1987, he was appointed as a consultant in 2002.

Clinical interests include ARDS, ICU acquired weakness, human models of ARDS and other aspects of critical illness, and extra-corporeal gas exchange techniques. 

His research is focussed on cellular and molecular mechanisms of acute lung injury and repair. Current, focus of research is the effect of mechanical forces on lung injury and repair; current models include cellular stretch, in vivo murine ventilator-induced lung injury (with Prof Takata, SORA ICL), EVLP and surgical models of acute lung injury and multiple organ dysfunction. He is involved in multidisciplinary translational research which integrates basic science with clinical studies, thereby providing novel insights into critical illness.



Ujma S, Carse S, Chetty A, et al., 2019, Surfactant Protein A Impairs Genital HPV16 Pseudovirus Infection by Innate Immune Cell Activation in A Murine Model, Pathogens, Vol:8

Akram K, Yates L, Mongey R, et al., 2019, Time-lapse imaging of alveologenesis in mouse precision-cut lung slices, Bio-protocol, Vol:9, ISSN:2331-8325

Griffiths M, Fan E, Baudouin SV, 2019, New UK guidelines for the management of adult patients with ARDS, Thorax, Vol:74, ISSN:0040-6376, Pages:931-933

Ng-Blichfeldt J-P, Gosens R, Dean C, et al., 2019, Regenerative pharmacology for COPD: breathing new life into old lungs, Thorax, Vol:74, ISSN:1468-3296, Pages:890-897


Kim SY, Mongey R, Wang P, et al., 2019, LSC-2019-A novel ex-vivo approach to study lung injury and repair, European-Respiratory-Society (ERS) International Congress, EUROPEAN RESPIRATORY SOC JOURNALS LTD, ISSN:0903-1936

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