Professor Mark Isalan - Deputy Head of Department

Tan SY, Guschin D, Davalos A, Lee YL, Snowden AW, Jouvenot Y, Zhang HS, Howes K, McNamara AR, Lai A, Ullman C, Reynolds L, Moore M, Isalan M, Berg LP, Campos B, Qi H, Spratt SK, Case CC, Pabo CO, Campisi J, Gregory PDet al., 2003, Zinc-finger protein-targeted gene regulation: Genomewide single-gene specificity, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 100, Pages: 11997-12002, ISSN: 0027-8424

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• Citations: 127

Reynolds L, Ullman C, Moore M, Isalan M, West MJ, Clapham P, Klug A, Choo Yet al., 2003, Repression of the HIV-1 5′ LTR promoter and inhibition of HIV-1 replication by using engineered zinc-finger transcription factors, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 100, Pages: 1615-1620, ISSN: 0027-8424

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• Citations: 101

Papworth M, Moore M, Isalan M, Minczuk M, Choo Y, Klug Aet al., 2003, Inhibition of herpes simplex virus 1 gene expression by designer zinc-finger transcription factors, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 100, Pages: 1621-1626, ISSN: 0027-8424

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• Citations: 60

Isalan M, Klug A, Choo Y, 2001, A rapid, generally applicable method to engineer zinc fingers illustrated by targeting the HIV-1 promoter, NATURE BIOTECHNOLOGY, Vol: 19, Pages: 656-660, ISSN: 1087-0156

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• Citations: 147

Isalan M, Patel SD, Balasubramanian S, Choo Yet al., 2001, Selection of zinc fingers that bind single-stranded telomeric DNA in the G-quadruplex conformation, BIOCHEMISTRY, Vol: 40, Pages: 830-836, ISSN: 0006-2960

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• Citations: 60

Isalan M, Choo Y, 2001, Rapid, high-throughput engineering of sequence-specific zinc finger DNA-binding proteins, DRUG-NUCLEIC ACID INTERACTIONS, Vol: 340, Pages: 593-609, ISSN: 0076-6879

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• Citations: 28

Isalan M, Choo Y, 2001, Engineering nucleic acid-binding proteins by phage display., Methods Mol Biol, Vol: 148, Pages: 417-429, ISSN: 1064-3745

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Choo Y, Isalan M, 2000, Advances in zinc finger engineering, CURRENT OPINION IN STRUCTURAL BIOLOGY, Vol: 10, Pages: 411-416, ISSN: 0959-440X

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• Citations: 69

Isalan M, Choo Y, 2000, Engineered zinc finger proteins that respond to DNA modification by <i>Hae</i>III and <i>Hha</i>I methyltransferase enzymes, JOURNAL OF MOLECULAR BIOLOGY, Vol: 295, Pages: 471-477, ISSN: 0022-2836

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• Citations: 15

Isalan M, Klug A, Choo Y, 1998, Comprehensive DNA recognition through concerted interactions from adjacent zinc fingers, BIOCHEMISTRY, Vol: 37, Pages: 12026-12033, ISSN: 0006-2960

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• Citations: 102

Isalan M, Choo Y, Klug A, 1997, Synergy between adjacent zinc fingers in sequence-specific DNA recognition, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol: 94, Pages: 5617-5621, ISSN: 0027-8424

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• Citations: 118